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Safety Data Sheet EN

p-Xylene

CAS 106-42-3
EC 203-396-5

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01

Identification

Product identifiers, regulatory numbers, and supplier information

Product Information

Product Name
p-Xylene
Product Code
158770000; 158770010; 158770025; 158770100; 158775000
Chemical Name
p-Xylene
Synonyms
1,4-Dimethylbenzene

Regulatory Identifiers

CAS Number
106-42-3 Check regulations →
EC Number
203-396-5 Check regulations →

Identified Uses

Laboratory chemicals.

Uses advised against

No Information available

Manufacturers & Suppliers

T

Thermo Fisher Scientific

Janssen Pharmaceuticalaan 3a, 2440 Geel, Belgium

F

Fisher Scientific UK

Bishop Meadow Road, Loughborough, Leicestershire LE11 5RG, United Kingdom

F

Fisher Scientific AG

distributor

Neuhofstrasse 11, CH 4153 Reinach

+41 (0) 56 618 41 11

Emergency Contacts

Emergency Contact

001-800-227-6701

Emergency Contact

+32 14 57 52 11

Emergency Contact

001-201-796-7100

Emergency Contact

+32 14 57 52 99

CHEMTREC

001-800-424-9300

CHEMTREC

001-703-527-3887

Tox Info Suisse

145

24hr

Tox Info Suisse

+41-44 251 51 51

Chemtrec

0800 564 402

24h

Chemtrec

+41-43 508 20 11

02

Hazard Identification

GHS classification, signal word, pictograms, and hazard statements

Classified danger

Hazard Classifications

Flam. Liq. Cat. 3 H226
Asp. Tox. Cat. 1 H304
Acute Tox. Cat. 4 H312
Acute Tox. Cat. 2 H315
Skin Irrit. Cat. 2 H319
Eye Irrit. Cat. 3 H335
STOT SE
Aquatic Chronic Cat. 3 H412

GHS Pictograms

GHS02 - Flammable

GHS02

GHS07 - Health hazard

GHS07

GHS08 - Serious health hazard

GHS08

Hazard Statements

H226 Flammable liquid and vapor
H304 May be fatal if swallowed and enters airways
H312 + H332 Harmful in contact with skin or if inhaled
H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation
H412 Harmful to aquatic life with long lasting effects

Precautionary Statements

P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking
P280 Wear protective gloves/protective clothing/eye protection/face protection
P301 + P330 + P331 IF SWALLOWED: Rinse mouth. Do NOT induce vomiting
P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing

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03

Composition / Information on Ingredients

Chemical components, concentration ranges, and hazardous substance identification

Type substance
Chemical Name CAS Number Concentration Hazardous
p-Xylene EC: 203-396-5 106-42-3 95% Yes
04

First Aid Measures

Emergency procedures for chemical exposure incidents

Inhalation

Remove to fresh air. If breathing is difficult, give oxygen. Do not use mouth-to-mouth method if victim ingested or inhaled the substance; give artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device. Immediate medical attention is required. Risk of serious damage to the lungs (by aspiration).

Symptoms: Difficulty in breathing.

Skin contact

Wash off immediately with plenty of water for at least 15 minutes. Immediate medical attention is required.

Eye contact

Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Immediate medical attention is required.

Ingestion

Aspiration hazard. Do NOT induce vomiting. Call a physician or poison control center immediately. If vomiting occurs naturally, have victim lean forward.

Immediate Medical Attention

Immediate medical attention is required.

Medical Treatment

Treat symptomatically.

05

Firefighting Measures

Extinguishing media, specific hazards, and firefighter protection

Suitable media

CO₂, dry chemical, dry sand, alcohol-resistant foam. Water mist may be used to cool closed containers.

Unsuitable media

Water may be ineffective.

Specific hazards

Flammable. Risk of ignition. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Containers may explode when heated. Thermal decomposition can lead to release of irritating gases and vapors. Keep product and empty container away from heat and sources of ignition.

Firefighter Protection

As in any fire, wear self-contained breathing apparatus pressure-demand, MSHA/NIOSH (approved or equivalent) and full protective gear.

06

Accidental Release Measures

Spill cleanup procedures, containment, and environmental protection

Emergency procedures

Avoid contact with skin, eyes or clothing.

Environmental

Avoid release to the environment.

Cleanup methods

Soak up with inert absorbent material.

Materials: inert absorbent material

—

Related Products

Similar products with comparable safety profiles

07

Handling and Storage

Safe handling precautions, storage conditions, and workplace requirements

Handling

Use only under a chemical fume hood. Use spark-proof tools and explosion-proof equipment. Wear personal protective equipment/face protection. Do not get in eyes, on skin, or on clothing. Do not breathe mist/vapors/spray. Do not ingest. If swallowed then seek immediate medical assistance. Keep away from open flames, hot surfaces and sources of ignition. Take precautionary measures against static discharges. Use only non-sparking tools.

Storage

Keep containers tightly closed in a dry, cool and well-ventilated place. Keep away from heat, sparks and flame. Flammables area.

Hygiene

Handle in accordance with good industrial hygiene and safety practice. Keep away from food, drink and animal feeding stuffs. Do not eat, drink or smoke when using this product. Remove and wash contaminated clothing and gloves, including the inside, before re-use. Wash hands before breaks and after work.

Fire prevention

Keep away from open flames, hot surfaces and sources of ignition. Take precautionary measures against static discharges. Use only non-sparking tools.

08

Exposure Controls / PPE

Occupational exposure limits, engineering controls, and protective equipment

Engineering

Use only under a chemical fume hood. Use explosion-proof electrical/ventilating/lighting/equipment. Ensure that eyewash stations and safety showers are close to the workstation location. Ensure adequate ventilation, especially in confined areas. Wherever possible, engineering control measures such as the isolation or enclosure of the process, the introduction of process or equipment changes to minimise release or contact, and the use of properly designed ventilation systems, should be adopted to control hazardous materials at source

Hands

Protective gloves. Glove material: Nitrile rubber, Neoprene, Natural rubber, PVC. Breakthrough time: See manufacturers recommendations. EU standard: EN 374. Glove comments: (minimum requirement). Inspect gloves before use. observe the instructions regarding permeability and breakthrough time which are provided by the supplier of the gloves. (Refer to manufacturer/supplier for information) gloves are suitable for the task: Chemical compatibility, Dexterity, Operational conditions, User susceptibility, e.g. sensitisation effects, also take into consideration the specific local conditions under which the product is used, such as the danger of cuts, abrasion. gloves with care avoiding skin contamination.

Eyes

Goggles (European standard - EN 166)

Respiratory

When workers are facing concentrations above the exposure limit they must use appropriate certified respirators. To protect the wearer, respiratory protective equipment must be the correct fit and be used and maintained properly. Large scale/emergency use: Use a NIOSH/MSHA or European Standard EN 136 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Recommended Filter type: Organic gases and vapours filter Type A Brown conforming to EN14387. Small scale/Laboratory use: Use a NIOSH/MSHA or European Standard EN 149:2001 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Recommended half mask:- Valve filtering: EN405; or; Half mask: EN140; plus filter, EN 141. When RPE is used a face piece Fit Test should be conducted

Skin/Body

Wear appropriate protective gloves and clothing to prevent skin exposure.

Environmental

Prevent product from entering drains. Do not allow material to contaminate ground water system.

09

Physical and Chemical Properties

Appearance, physical state, melting point, boiling point, and material characteristics

Language Code
---
Physical State
Liquid
Physical State Data
liquid
State Under Standard Conditions
---
Appearance
Colorless
Colour
---
Colour Intensity
---
Form
---
Odor
aromatic
Odor Threshold
No data available
Ph
Not applicable
Melting Point
13 °C / 55.4 °F
Boiling Point
138 °C / 280.4 °F
Flash Point
25 °C / 77 °F
Freezing Point
---
Softening Point
No data available
Solidification Point
---
Cloud Point
---
Crystallisation Point
---
Relative Evaporation Rate
---
Evaporation Rate
---
Vapor Pressure
8 mbar @ 20 °C
Vapor Density
---
Relative Density
---
Bulk Density
Not applicable
Density
0.866
Flammability
Flammable
Upper Explosive Limit
7 Vol%
Lower Explosive Limit
1.1 Vol%
Explosive Limits
---
Auto Ignition Temperature
465 °C / 869 °F
Decomposition Temperature
No data available
Solubility
---
Partition Coefficient
p-Xylene: 3.2 (log Pow)
Solubility In Water
0.2 g/L (20°C)
Solubility In Fat
---
Molecular Weight
106.17
Voc Content
---
Metal Corrosion
---
Dynamic Viscosity
0.648 mPa.s (20°C)
Kinematic Viscosity
---
Properties Status
---
10

Stability and Reactivity

Chemical stability, hazardous reactions, and incompatible materials

Stability

Stable under normal conditions.

Reactivity

None known, based on information available

Hazardous reactions

Hazardous polymerization does not occur. None under normal processing.

Avoid

Incompatible products. Excess heat. Keep away from open flames, hot surfaces and sources of ignition.

Incompatible

Strong oxidizing agents. Strong acids. Strong bases.

Decomposition

Carbon monoxide (CO). Carbon dioxide (CO₂). Hydrocarbons. Aldehydes.

12

Ecological Information

Environmental toxicity, biodegradation, and bioaccumulation data

12.1. Toxicity

Ecotoxicity effects Do not empty into drains. The product contains following substances which are hazardous for the environment. Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. Contains a substance which is: Toxic to aquatic organisms. | Component | Freshwater Fish | Water Flea | Freshwater Algae | | --- | --- | --- | --- | | p-Xylene | LC50: = 8.8 mg/L, 96h semi-static (Poecilia reticulata) LC50: = 2.6 mg/L, 96h static (Oncorhynchus mykiss) LC50: = 2.6 mg/L, 96h (Oncorhynchus mykiss) LC50: 7.2 - 9.9 mg/L, 96h static (Pimephales promelas) | EC50: 3.55 - 6.31 mg/L, 48h Static (Daphnia magna) | EC50: = 3.2 mg/L, 72h static (Pseudokirchneriella subcapitata) | | Component | Microtox | M-Factor | | --- | --- | --- | | p-Xylene | EC50 = 5.7 mg/L 30 min | |

The product is hazardous to the environment, specifically toxic to aquatic organisms with potential long-term adverse effects.

12.2. Persistence and degradability

Expected to be biodegradable Persistence Insoluble in water, Persistence is unlikely, based on information available. Degradation in sewage treatment plant Contains substances known to be hazardous to the environment or not degradable in waste water treatment plants.

The substance is expected to be biodegradable, though it is insoluble in water. It contains substances that may be hazardous to the environment or not degradable in sewage treatment plants.

12.3. Bioaccumulative potential

May have some potential to bioaccumulate | Component | log Pow | Bioconcentration factor (BCF) | | --- | --- | --- | | p-Xylene | 3.2 | 2.2 dimensionless |

12.4. Mobility in soil

Spillage unlikely to penetrate soil The product is insoluble and floats on water The product contains volatile organic compounds (VOC) which will evaporate easily from all surfaces. Is not likely mobile in the environment due its low water solubility. Will likely be mobile in the environment due to its volatility.

The product is insoluble and floats on water. It contains volatile organic compounds that evaporate easily. Mobility is limited by low water solubility but potentially increased by volatility.

12.5. Results of PBT and vPvB assessment

Substance is not considered persistent, bioaccumulative and toxic (PBT) / very persistent and very bioaccumulative (vPvB).

The substance is not considered persistent, bioaccumulative and toxic (PBT) / very persistent and very bioaccumulative (vPvB).

12.6. Endocrine disrupting properties

Endocrine Disruptor Information This product does not contain any known or suspected endocrine disruptors

This product does not contain any known or suspected endocrine disruptors

12.7. Other adverse effects

Persistent Organic Pollutant Ozone Depletion Potential This product does not contain any known or suspected substance This product does not contain any known or suspected substance

This product does not contain any known or suspected substance regarding Persistent Organic Pollutant or Ozone Depletion Potential.

13

Disposal Considerations

Waste treatment methods, disposal recommendations, and waste codes

The data for this section has not been processed yet.

14

Transport Information

UN numbers, shipping names, transport classes, and regulatory requirements

UN Number
UN1307
Shipping Name
XYLENES
Transport Class
3
Packing Group
III
15

Regulatory Information

Chemical regulations, safety assessments, and compliance status

Safety, health and environmental regulations/legislation specific for the substance or mixture

Chemical Safety Assessment Not performed

Take note of Directive 98/24/EC on the protection of the health and safety of workers from the risks related to chemical agents at work. Take note of Directive 2000/39/EC establishing a first list of indicative occupational exposure limit values.

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Frequently Asked Questions

Common questions about safety, handling, and properties

What other names is p-Xylene known by?

p-Xylene is also known as: 1,4-Dimethylbenzene

What is the hazard signal word for p-Xylene?

The signal word is danger.

What is the physical form of p-Xylene?

p-Xylene is a liquid appearing as colorless . It has aromatic odor.

What is p-Xylene used for?

Laboratory chemicals.

What are the hazard statements for p-Xylene?

This substance has 7 hazard statements:

  • H226: Flammable liquid and vapor
  • H304: May be fatal if swallowed and enters airways
  • H312 + H332: Harmful in contact with skin or if inhaled
  • H315: Causes skin irritation
  • H319: Causes serious eye irritation
  • H335: May cause respiratory irritation
  • H412: Harmful to aquatic life with long lasting effects

What is the melting point of p-Xylene?

The melting point is 13 °C / 55.4 °F and the boiling point is 138 °C / 280.4 °F.