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Safety Data Sheet EN

2-Ketoglutaric acid

CAS 328-50-7
EC 206-330-3

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01

Identification

Product identifiers, regulatory numbers, and supplier information

Product Information

Product Name
2-Ketoglutaric acid
Product Code
A10256
Chemical Name
2-Ketoglutaric acid
Synonyms
2-Oxoglutaric acid; 2-Oxopentanedioic acid

Regulatory Identifiers

CAS Number
328-50-7 Check regulations →
EC Number
206-330-3 Check regulations →

Identified Uses

Laboratory chemicals.

Uses advised against

No Information available

Manufacturers & Suppliers

A

Avocado Research Chemicals Ltd. (Part of Thermo Fisher Scientific)

manufacturer

Shore Road, Heysham, Lancashire, LA3 2XY, United Kingdom

+44 (0) 1524 850506

Emergency Contacts

Emergency Contact

001-800-227-6701

Emergency Contact

+32 14 57 52 11

Emergency Contact

001-201-796-7100

Emergency Contact

+32 14 57 52 99

CHEMTREC

001-800-424-9300

CHEMTREC

001-703-527-3887

02

Hazard Identification

GHS classification, signal word, pictograms, and hazard statements

Classified danger

Hazard Classifications

Eye Dam. Cat. 1 H318

GHS Pictograms

GHS05 - Corrosive

GHS05

Hazard Statements

H318 Causes serious eye damage

Precautionary Statements

P280 Wear eye protection/ face protection
P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing
P310 Immediately call a POISON CENTER or doctor/physician

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03

Composition / Information on Ingredients

Chemical components, concentration ranges, and hazardous substance identification

Type substance
Chemical Name CAS Number Concentration Hazardous
Pentanedioic acid, 2-oxo- EC: 206-330-3 328-50-7 98% Yes
04

First Aid Measures

Emergency procedures for chemical exposure incidents

Inhalation

Remove to fresh air. If not breathing, give artificial respiration. Get medical attention if symptoms occur.

Skin contact

Wash off immediately with plenty of water for at least 15 minutes. If skin irritation persists, call a physician.

Eye contact

Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Get medical attention.

Symptoms: Causes severe eye damage.

Ingestion

Clean mouth with water and drink afterwards plenty of water. Get medical attention if symptoms occur.

Symptoms: Ingestion causes severe swelling, severe damage to the delicate tissue and danger of perforation

Immediate Medical Attention

Get medical attention if symptoms occur.

Medical Treatment

Treat symptomatically.

05

Firefighting Measures

Extinguishing media, specific hazards, and firefighter protection

Suitable media

Water spray, carbon dioxide (CO2), dry chemical, alcohol-resistant foam.

Unsuitable media

No information available.

Specific hazards

Thermal decomposition can lead to release of irritating gases and vapors.

Firefighter Protection

As in any fire, wear self-contained breathing apparatus pressure-demand, MSHA/NIOSH (approved or equivalent) and full protective gear.

06

Accidental Release Measures

Spill cleanup procedures, containment, and environmental protection

Emergency procedures

Ensure adequate ventilation. Use personal protective equipment as required.

Environmental

Should not be released into the environment.

Cleanup methods

Sweep up and shovel into suitable containers for disposal.

Related Products

Similar products with comparable safety profiles

07

Handling and Storage

Safe handling precautions, storage conditions, and workplace requirements

Handling

Wear personal protective equipment/face protection. Ensure adequate ventilation. Do not get in eyes, on skin, or on clothing. Avoid ingestion and inhalation. Avoid dust formation.

Storage

Keep in a dry place. Keep refrigerated. Keep containers tightly closed in a dry, cool and well-ventilated place. Corrosives area.

Hygiene

Handle in accordance with good industrial hygiene and safety practice. Keep away from food, drink and animal feeding stuffs. Do not eat, drink or smoke when using this product. Remove and wash contaminated clothing and gloves, including the inside, before re-use. Wash hands before breaks and after work.

08

Exposure Controls / PPE

Occupational exposure limits, engineering controls, and protective equipment

Engineering

Ensure adequate ventilation, especially in confined areas. Ensure that eyewash stations and safety showers are close to the workstation location. Wherever possible, engineering control measures such as the isolation or enclosure of the process, the introduction of process or equipment changes to minimise release or contact, and the use of properly designed ventilation systems, should be adopted to control hazardous materials at source

Hands

Protective gloves. Glove material: Natural rubber, Butyl rubber, Nitrile rubber, Neoprene, PVC. Breakthrough time: See manufacturers recommendations. EU standard: EN 374. Glove comments: (minimum requirement). Inspect gloves before use. Please observe the instructions regarding permeability and breakthrough time which are provided by the supplier of the gloves. (Refer to manufacturer/supplier for information). Ensure gloves are suitable for the task: Chemical compatability, Dexterity, Operational conditions, User susceptibility, e.g. sensitisation effects, also take into consideration the specific local conditions under which the product is used, such as the danger of cuts, abrasion. Remove gloves with care avoiding skin contamination.

Eyes

Goggles (European standard - EN 166)

Respiratory

When workers are facing concentrations above the exposure limit they must use appropriate certified respirators. To protect the wearer, respiratory protective equipment must be the correct fit and be used and maintained properly. Large scale/emergency use: Use a NIOSH/MSHA or European Standard EN 136 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Recommended Filter type: Particulates filter conforming to EN 143. Small scale/Laboratory use: Use a NIOSH/MSHA or European Standard EN 149:2001 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Recommended half mask: Valve filtering: EN405; or; Half mask: EN140; plus filter, EN 141. When RPE is used a face piece Fit Test should be conducted

Skin/Body

Long sleeved clothing.

Environmental

No information available.

09

Physical and Chemical Properties

Appearance, physical state, melting point, boiling point, and material characteristics

Physical State
Powder Solid
Physical State Data
solid
State Under Standard Conditions
---
Appearance
Off-white
Colour
---
Colour Intensity
---
Form
---
Odor
Odorless
Odor Threshold
No data available
Ph
1.5
Melting Point
113 - 115 °C / 235.4 - 239 °F
Boiling Point
No information available
Flash Point
No information available Method - No information available
Freezing Point
---
Softening Point
No data available
Solidification Point
---
Cloud Point
---
Crystallisation Point
---
Relative Evaporation Rate
---
Evaporation Rate
Not applicable - Solid
Vapor Pressure
No data available
Vapor Density
Not applicable
Relative Density
---
Bulk Density
No data available
Density
No data available
Flammability
No information available
Upper Explosive Limit
---
Lower Explosive Limit
---
Explosive Limits
---
Auto Ignition Temperature
Not applicable
Decomposition Temperature
No data available
Solubility
---
Partition Coefficient
No data available
Solubility In Water
Very soluble
Solubility In Fat
---
Molecular Weight
146.1
Voc Content
---
Metal Corrosion
---
Dynamic Viscosity
---
Kinematic Viscosity
---
Properties Status
---
10

Stability and Reactivity

Chemical stability, hazardous reactions, and incompatible materials

Stability

Stable under normal conditions.

Reactivity

None known, based on information available

Hazardous reactions

None under normal processing. Hazardous Polymerization: No information available.

Avoid

Incompatible products.

Incompatible

Bases. Reducing Agent.

Decomposition

Carbon monoxide (CO). Carbon dioxide (CO₂).

12

Ecological Information

Environmental toxicity, biodegradation, and bioaccumulation data

The data for this section has not been processed yet.

13

Disposal Considerations

Waste treatment methods, disposal recommendations, and waste codes

The data for this section has not been processed yet.

14

Transport Information

UN numbers, shipping names, transport classes, and regulatory requirements

15

Regulatory Information

Chemical regulations, safety assessments, and compliance status

The data for this section has not been processed yet.

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Frequently Asked Questions

Common questions about safety, handling, and properties

What other names is 2-Ketoglutaric acid known by?

2-Ketoglutaric acid is also known as: 2-Oxoglutaric acid; 2-Oxopentanedioic acid

What is the hazard signal word for 2-Ketoglutaric acid?

The signal word is danger.

What is the physical form of 2-Ketoglutaric acid?

2-Ketoglutaric acid is a powder solid appearing as off-white . It has odorless odor.

What is 2-Ketoglutaric acid used for?

Laboratory chemicals.

What are the hazard statements for 2-Ketoglutaric acid?

This substance has 1 hazard statement:

  • H318: Causes serious eye damage

What is the melting point of 2-Ketoglutaric acid?

The melting point is 113 - 115 °C / 235.4 - 239 °F and the boiling point is No information available.