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Safety Data Sheet EN

Folate RBC Elecsys cobas e 100

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01

Identification

Product identifiers, regulatory numbers, and supplier information

Product Information

Product Name
Folate RBC Elecsys cobas e 100
Product Code
05944295160

Regulatory Identifiers

CAS Number
N/A

Manufacturers & Suppliers

R

Roche Diagnostics

manufacturer

9115 Hague Road 46250 Indianapolis IN

1-800-428-5074

Emergency Contacts

CHEMTREC

1-800-424-9300

CHEMTREC

1-703-527-3887

02

Hazard Identification

GHS classification, signal word, pictograms, and hazard statements

Classified danger

GHS Pictograms

GHS05 - Corrosive

GHS05

GHS08 - Serious health hazard

GHS08

Hazard Statements

H290 May be corrosive to metals.
H360 May damage fertility or the unborn child.

Precautionary Statements

P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P234 Keep only in original container.
P281 Use personal protective equipment as required.
P308 + P313 IF exposed or concerned: Get medical advice/ attention.
P390 Absorb spillage to prevent material damage.
P405 Store locked up.
P406 Store in corrosive resistant stainless steel container with a resistant inner liner.
P501 Dispose of contents/ container to an approved waste disposal plant.

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03

Composition / Information on Ingredients

Chemical components, concentration ranges, and hazardous substance identification

Type mixture
Chemical Name CAS Number Concentration Hazardous
mesna 19767-45-4 1 - 5% No
sodium hydroxide 1310-73-2 1 - 5% Yes
sucrose 57-50-1 1 - 5% No
boric acid 10043-35-3 0.1 - 1% Yes
boric acid 10043-35-3 0.1 - 1% Yes
04

First Aid Measures

Emergency procedures for chemical exposure incidents

Inhalation

Move to fresh air. If unconscious place in recovery position and seek medical advice. If symptoms persist, call a physician.

Skin contact

Immediate medical treatment is necessary as untreated wounds from corrosion of the skin heal slowly and with difficulty. If on skin, rinse well with water. If on clothes, remove clothes.

Eye contact

In the case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Continue rinsing eyes during transport to hospital. Remove contact lenses. Protect unharmed eye. Keep eye wide open while rinsing. If eye irritation persists, consult a specialist.

Symptoms: Small amounts splashed into eyes can cause irreversible tissue damage and blindness.

Ingestion

Clean mouth with water and drink afterwards plenty of water. Keep respiratory tract clear. Do NOT induce vomiting. Do not give milk or alcoholic beverages. Never give anything by mouth to an unconscious person. If symptoms persist, call a physician. Take victim immediately to hospital. Rinse mouth with water.

Immediate Medical Attention

Take victim immediately to hospital.

Medical Treatment

The first aid procedure should be established in consultation with the doctor responsible for industrial medicine.

05

Firefighting Measures

Extinguishing media, specific hazards, and firefighter protection

Suitable media

Use extinguishing measures that are appropriate to local circumstances and the surrounding environment.

Unsuitable media

High volume water jet

Specific hazards

Do not allow run-off from fire fighting to enter drains or water courses.

Firefighter Protection

Wear self-contained breathing apparatus for firefighting if necessary.

06

Accidental Release Measures

Spill cleanup procedures, containment, and environmental protection

Emergency procedures

Use personal protective equipment. Refer to protective measures listed in sections 7 and 8.

Environmental

Prevent product from entering drains. Prevent further leakage or spillage if safe to do so.

Cleanup methods

Soak up with inert absorbent material (e.g. sand, silica gel, acid binder, universal binder, sawdust).

Materials: inert absorbent material (e.g. sand, silica gel, acid binder, universal binder, sawdust)

—

Related Products

Similar products with comparable safety profiles

F

Folate RBC CS Elecsys

---

A

AMH Elecsys cobas e 100

---

E

Estradiol G3 Elecsys cobas e 100

---

C

CMV IgG Elecsys cobas e 100

---

F

Folate III

---

F

Folate III CalCheck

---

F

Folic acid

CAS: 59-30-3

F

Folic Acid

---

07

Handling and Storage

Safe handling precautions, storage conditions, and workplace requirements

Handling

Do not breathe vapours/dust. Avoid exposure - obtain special instructions before use. Avoid contact with skin and eyes. For personal protection see section 8. Smoking, eating and drinking should be prohibited in the application area.

Storage

Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage. Observe label precautions.

Hygiene

Smoking, eating and drinking should be prohibited in the application area.

08

Exposure Controls / PPE

Occupational exposure limits, engineering controls, and protective equipment

09

Physical and Chemical Properties

Appearance, physical state, melting point, boiling point, and material characteristics

Physical State
liquid
Physical State Data
liquid
State Under Standard Conditions
---
Appearance
liquid
Colour
---
Colour Intensity
---
Form
---
Odor
---
Odor Threshold
---
Ph
5.5
Melting Point
No data available
Boiling Point
No data available
Flash Point
does not flash
Freezing Point
---
Softening Point
---
Solidification Point
---
Cloud Point
---
Crystallisation Point
---
Relative Evaporation Rate
---
Evaporation Rate
---
Vapor Pressure
---
Vapor Density
---
Relative Density
---
Bulk Density
---
Density
1.02 g/cm3
Flammability
The product is not flammable.
Upper Explosive Limit
No data available
Lower Explosive Limit
No data available
Explosive Limits
---
Auto Ignition Temperature
No data available
Decomposition Temperature
No data available
Solubility
---
Partition Coefficient
---
Solubility In Water
completely miscible
Solubility In Fat
---
Molecular Weight
---
Voc Content
---
Metal Corrosion
---
Dynamic Viscosity
---
Kinematic Viscosity
---
Properties Status
---
10

Stability and Reactivity

Chemical stability, hazardous reactions, and incompatible materials

Stability

Stable under normal conditions.

Reactivity

No dangerous reaction known under conditions of normal use.

Hazardous reactions

No dangerous reaction known under conditions of normal use.

Avoid

No data available

Incompatible

No data available

Decomposition

No hazardous decomposition products are known.

12

Ecological Information

Environmental toxicity, biodegradation, and bioaccumulation data

Ecotoxicity

Product: Ecotoxicology Assessment Toxicity Data on Soil : Not expected to adsorb on soil. Other organisms relevant to the environment : No data available Components: mesna: Toxicity to fish : Remarks: No data available Toxicity to daphnia and other aquatic invertebrates : Remarks: No data available Toxicity to algae : Remarks: No data available Toxicity to bacteria : Remarks: No data available Ecotoxicology Assessment Toxicity Data on Soil : Not expected to adsorb on soil. Other organisms relevant to the environment : No data available

Persistence and degradability

Components: mesna: Biodegradability : Remarks: No data available Biochemical Oxygen Demand (BOD) : Remarks: No data available Chemical Oxygen Demand (COD) : Remarks: No data available Dissolved organic carbon (DOC) : Remarks: No data available Physico-chemical removability : Remarks: No data available

Bioaccumulative potential

Components: mesna: Bioaccumulation : Remarks: No data available Partition coefficient: n-octanol/water : Remarks: No data available

Mobility in soil

Components: mesna: Mobility : Remarks: No data available Distribution among environmental compartments : Remarks: No data available

Other adverse effects

Product: Regulation 40 CFR Protection of Environment; Part 82 Protection of Stratospheric Ozone - CAA Section 602 Class I Substances Remarks This product neither contains, nor was manufactured with a Class I or Class II ODS as defined by the U.S. Clean Air Act Section 602 (40 CFR 82, Subpt. A, App.A + B). Components: mesna: Environmental fate and pathways : No data available Adsorbed organic bound halogens (AOX) : Remarks: No data available

Ecotoxicity

Toxicity to fish : LC50 (Oncorhynchus mykiss (rainbow trout)): 45.4 mg/l Exposure time: 96 h : LC50 (Leuciscus idus (Golden orfe)): ca. 7 mg/l Toxicity to daphnia and other aquatic invertebrates : EC50 (Daphnia magna (Water flea)): 40.38 mg/l Exposure time: 48 h

12.1 Toxicity

Acute aquatic toxicity : This product has no known ecotoxicological effects. Chronic aquatic toxicity : This product has no known ecotoxicological effects. Toxicity Data on Soil : Not expected to adsorb on soil. Other organisms relevant to the environment : No data available

12.2 Persistence and degradability

No data available

12.3 Bioaccumulative potential

No data available

12.4 Mobility in soil

No data available

12.7 Other adverse effects

No data available

12.4 Mobility in soil

Toxicity Data on Soil : Not expected to adsorb on soil.

Not expected to adsorb on soil.

Ecotoxicity

Toxicity to fish : LC50: > 100 mg/l Exposure time: 96 h Toxicity to fish (Chronic toxicity) : > 1 mg/l Ecotoxicology Assessment Acute aquatic toxicity : This product has no known ecotoxicological effects. Chronic aquatic toxicity : This product has no known ecotoxicological effects. Toxicity Data on Soil : Not expected to adsorb on soil. Other organisms relevant to the environment : No data available

Persistence and degradability

No data available

Bioaccumulative potential

Partition coefficient: n-octanol/water : log Pow: -3.67

Mobility in soil

Not expected to adsorb on soil.

Ecotoxicity

Other organisms relevant to the environment : No data available

Mobility in soil

No data available. Toxicity Data on Soil : Not expected to adsorb on soil.

Other adverse effects

No data available

12.1 Toxicity

Toxicity to fish : LC50 (Gambusia affinis (Mosquito fish)): 5,600 mg/l Exposure time: 96 h Toxicity to daphnia and other aquatic invertebrates : EC50 (Daphnia magna (Water flea)): 133 mg/l Exposure time: 48 h

Persistence and degradability

boric acid: Biodegradability : Remarks: The methods for determining biodegradability are not applicable to inorganic substances. Impact on Sewage Treatment : Do not discharge product into the aquatic environment without pretreatment (biological treatment plant).

Bioaccumulative potential

Components: boric acid: Bioaccumulation : Remarks: Due to the distribution coefficient n-octanol/water, accumulation in organisms is not expected. Partition coefficient: n-octanol/water : log Pow: -0.76 (25 °C)

Ecotoxicity

sodium hydroxide: LC50 (Oncorhynchus mykiss (rainbow trout)): 45.4 mg/l, Exposure time: 96 h; LC50 (Leuciscus idus (Golden orfe)): ca. 7 mg/l; EC50 (Daphnia magna (Water flea)): 40.38 mg/l, Exposure time: 48 h. sucrose: LC50: > 100 mg/l, Exposure time: 96 h; Chronic toxicity: > 1 mg/l. boric acid: LC50 (Gambusia affinis (Mosquito fish)): 5,600 mg/l, Exposure time: 96 h; EC50 (Daphnia magna (Water flea)): 133 mg/l, Exposure time: 48 h.

Persistence and degradability

No data available. boric acid: The methods for determining biodegradability are not applicable to inorganic substances.

Bioaccumulative potential

sucrose: log Pow: -3.67. boric acid: log Pow: -0.76 (25 °C). Due to the distribution coefficient n-octanol/water, accumulation in organisms is not expected.

Mobility in soil

No data available. Toxicity Data on Soil: Not expected to adsorb on soil.

Other adverse effects

This product neither contains, nor was manufactured with a Class I or Class II ODS as defined by the U.S. Clean Air Act Section 602 (40 CFR 82, Subpt. A, App.A + B).

Ecotoxicity

Toxicity to fish : LC50 (Gambusia affinis (Mosquito fish)): 5,600 mg/l Exposure time: 96 h Toxicity to daphnia and other aquatic invertebrates : EC50 (Daphnia magna (Water flea)): 133 mg/l Exposure time: 48 h Ecotoxicology Assessment Acute aquatic toxicity : This product has no known ecotoxicological effects. Chronic aquatic toxicity : This product has no known ecotoxicological effects. Toxicity Data on Soil : Not expected to adsorb on soil. Other organisms relevant to the environment : No data available

Persistence and degradability

Biodegradability : Remarks: The methods for determining biodegradability are not applicable to inorganic substances. Impact on Sewage Treatment : Do not discharge product into the aquatic environment without pretreatment (biological treatment plant).

Bioaccumulative potential

boric acid: Bioaccumulation : Remarks: Due to the distribution coefficient n-octanol/water, accumulation in organisms is not expected. Partition coefficient: n-octanol/water : log Pow: -0.76 (25 °C)

Mobility in soil

No data available

Other adverse effects

No data available
13

Disposal Considerations

Waste treatment methods, disposal recommendations, and waste codes

Treatment

Send to a licensed waste management company. Can be disposed as waste water, when in compliance with local regulations.

Disposal

Do not contaminate ponds, waterways or ditches with chemical or used container.

14

Transport Information

UN numbers, shipping names, transport classes, and regulatory requirements

UN Number
UN1824
Shipping Name
Sodium hydroxide solution
Transport Class
8
Packing Group
II
15

Regulatory Information

Chemical regulations, safety assessments, and compliance status

?

Frequently Asked Questions

Common questions about safety, handling, and properties

What is the hazard signal word for Folate RBC Elecsys cobas e 100?

The signal word is danger.

What is the physical form of Folate RBC Elecsys cobas e 100?

Folate RBC Elecsys cobas e 100 is a liquid appearing as liquid .

What are the hazard statements for Folate RBC Elecsys cobas e 100?

This substance has 2 hazard statements:

  • H290: May be corrosive to metals.
  • H360: May damage fertility or the unborn child.

What is the melting point of Folate RBC Elecsys cobas e 100?

The melting point is No data available and the boiling point is No data available.