Identification
Product identifiers, regulatory numbers, and supplier information
Product Information
- Product Name
- ElisaRSR™ ZnT8 Ab™
- Product Code
- ZnT8/96
Regulatory Identifiers
- CAS Number
- N/A
Identified Uses
Quantitative determination of autoantibodies to ZnT8 in human serum
Manufacturers & Suppliers
RSR Limited
manufacturer
Parc Ty Glas, Llanishen, Cardiff, CF14 5DU, United Kingdom
+4429 2068 9299
Emergency Contacts
MHRA Medical Devices Adverse Incident Centre
+4420 3080 7080
Hazard Identification
GHS classification, signal word, pictograms, and hazard statements
Hazard Classifications
GHS Pictograms
GHS07
Hazard Statements
Precautionary Statements
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Composition / Information on Ingredients
Chemical components, concentration ranges, and hazardous substance identification
| Chemical Name | CAS Number | Concentration | Hazardous |
|---|---|---|---|
| K-Blue® Advanced TMB Substrate | --- | 100% | Yes |
| 2-pyrrolidone EC: 210-483-1 | 616-45-5 | 1 - 10% | Yes |
| Urea Hydrogen Peroxide EC: 204-701-4 | 124-43-6 | 0.1% | Yes |
| StabilZyme® HRP Conjugate Stabilizer | --- | 99% | Yes |
| 2-methyl-2H-isothiazol-3-one | 2682-20-4 | 0.0126% | Yes |
| CMIT/MIT | 55965-84-9 | 0.0024% | Yes |
| 2-Chloroacetamide EC: 201-174-2 | 79-07-2 | 0.01 - 0.1% | Yes |
| Sulphuric Acid EC: 231-639-5 | 7664-93-9 | 5% | Yes |
| 2-Methyl-4-isothiazolin-3-one hydrochloride (MIT) EC: 247-499-3 | 26172-54-3 | 0.1% | Yes |
| Sodium Azide EC: 247-852-1 | 26628-22-8 | 0.1% | Yes |
First Aid Measures
Emergency procedures for chemical exposure incidents
Remove from exposure, rest and keep warm.
Wash off skin thoroughly with water for at least 15 minutes. Remove contaminated clothing.
Separate eyelids with fingers and flush eye with copious amounts of water for at least 15 minutes.
If patient is conscious, wash out mouth with water and give plenty of water to drink.
Immediate Medical Attention
In severe cases or if skin is broken, OBTAIN MEDICAL ATTENTION. OBTAIN MEDICAL ATTENTION (for eye contact). If breathing becomes difficult, OBTAIN MEDICAL ATTENTION. OBTAIN MEDICAL ATTENTION (for ingestion).
Firefighting Measures
Extinguishing media, specific hazards, and firefighter protection
Use water, dry powder or foam as appropriate to supporting fire.
May evolve toxic fumes in fire.
Firefighter Protection
Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
Accidental Release Measures
Spill cleanup procedures, containment, and environmental protection
Ventilate area and avoid breathing vapours, mist or gas.
Prevent further leakage or spillage if safe to do so.
Wipe up liquid spills with absorbent paper. For solid spills, sweep up without raising dust. Once pick up is complete, wash site with detergent and water.
Materials: absorbent paper, detergent and water
Related Products
Similar products with comparable safety profiles
Handling and Storage
Safe handling precautions, storage conditions, and workplace requirements
Material of human origin has been tested and found non-reactive for HIV 1 and 2 and HCV antibodies and HBsAg. All animal sourced material has been obtained from animals certified as healthy and free from disease. However all potentially biohazardous components should be considered as potentially infectious. Level 2 containment should be applied. Do not eat, drink or smoke in the laboratory. Do not pipette by mouth. Avoid skin and eye contact. Wear appropriate protective clothing as described in sub section 8.2. Avoid the use of needles or other sharp implements. Avoid prolonged or repeated exposure. Wash hands thoroughly after handling.
Keep containers tightly closed. Store in a dry place in the box supplied at a temperature between +2 and +8°C.
Do not eat, drink or smoke in the laboratory. Do not pipette by mouth. Wash hands thoroughly after handling.
Exposure Controls / PPE
Occupational exposure limits, engineering controls, and protective equipment
Good laboratory practice should be followed (see Section 7).
Chemical resistant gloves to be used in accordance with standard EN374 derived from Regulation (EU) 2016/425. Inspect gloves for damage prior to use and change if any sign of degradation. Proper glove removal technique must be used. Wash hands after use. The following are suitable as protective gloves: - Glove materials: Nitrile rubber - Glove Thickness: >= 0.4 mm thickness - Permeation Time: >= 480 min. This recommendation is advisory only and should be evaluated by the customer for suitability in their specific situation.
Chemical safety glasses or goggles conforming to appropriate government standards such as EN166 (EU) or NIOSH (US).
Local exhaust.
Chemical resistant gloves to be used in accordance with standard EN374 derived from Regulation (EU) 2016/425. Inspect gloves for damage prior to use and change if any sign of degradation. Proper glove removal technique must be used. Wash hands after use.
Prevent further leakage or spillage if safe to do so. Prevent any reagents from entering drains.
Physical and Chemical Properties
Appearance, physical state, melting point, boiling point, and material characteristics
Stability and Reactivity
Chemical stability, hazardous reactions, and incompatible materials
All components of the ElisaRSR™ ZnT8 Ab™ kit have been found stable for stated shelf life when stored under the recommended conditions.
Data is not available on the reactivity of individual kit components but is given, where available, on ingredients listed in sub section 3.2. Sulphuric acid is a strong oxidising agent and has a corrosive effect. There is no data available on the other ingredients.
No hazardous reactions known for kit components although, hazardous reactions occur for the following ingredients listed in sub section 3.2: Sodium Azide: Risk of explosion and/or toxic gas formation exists with heavy metals, bromine, lead, chromyl chloride, dichloromethane, dimethylsulfate, halogenated hydrocarbon, acid, carbon disulphide, sulphuric acid, copper and nitric acid. Generates dangerous gases or fumes with acids and water, leading to the release of hydrazoic acid. Violent reactions possible with nitrates, benzoyl chloride and potassium nitrate. Sulphuric Acid: Violent reactions possible with: Water, alkali metals, alkali compounds, ammonia, aldehydes, acetonitrile, alkaline earth metals, alkalines, acids, alkaline earth compounds, metals, metal alloys, oxides of phosphorus, phosphorus, hydrides, halogen-halogen compounds, oxyhalogenic compounds, permanganates, nitrates, carbides, combustible substances, organic solvent, acetylcholine, nitriles, organic nitro compounds, anilines, peroxides, picrates, nitrides, lithium silicide, iron (III) compounds, bromates, chlorates, amines, perchlorates and hydrogen peroxide.
Peroxidase substrate (TMB) is light sensitive and therefore the bottle should be kept tightly closed when not in use and stored in a dark place. Peroxidase substrate (TMB) must also be kept away from extreme temperatures. Proteins, sodium azide and sulphuric acid are heat sensitive and storage or use at the improper temperature may compromise the integrity of the kit.
2-Chloroacetamide: Strong oxidising agents, strong acids, strong bases and strong reducing agents; K-Blue® Advanced TMB Substrate: No data available; MIT: Strong oxidising agents; Sodium Azide: Aluminium and heavy metals; StabilZyme® HRP Conjugate Stabilizer: None known; Sulphuric Acid: Animal and vegetable tissues. Metals. Contact with metals liberates hydrogen gas.
No decomposition products are formed if kit is stored and used under the specified storage and handling conditions. May evolve toxic fumes in fire. Thermal decomposition products are not known for the kit components but hazardous combustion products of the ingredients listed in sub section 3.2 can be found in sub section 5.2.
Ecological Information
Environmental toxicity, biodegradation, and bioaccumulation data
12.1 Toxicity
12.1 Toxicity
12.1 Toxicity
12.1 Toxicity
12.1 Toxicity
12.1 Toxicity
12.2 Persistence and degradability
12.2 Persistence and degradability
12.2 Persistence and degradability
12.3 Bioaccumulative potential
12.3 Bioaccumulative potential
12.3 Bioaccumulative potential
12.4 Mobility in soil
12.5 Results of PBT and vPvB assessment
2-Chloroacetamide is not considered to be persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of ≥0.1%.
12.6 Endocrine disrupting properties
The ingredients listed in sub section 3.2 do not have endocrine disrupting properties with respect to non-target organisms as it does not meet the criteria set out in section B of Regulation (EU) No 2017/2100.
12.7 Other adverse effects
The ecological risk is considered minimal as ingredient concentrations are below hazardous limits, though large quantities should not be disposed of in drains.
Disposal Considerations
Waste treatment methods, disposal recommendations, and waste codes
Chemical and biological residues are classified as special waste and as such, are covered by regulations which may vary according to location. Contact your local waste disposal authority for advice or pass to a licensed disposal company.
Contact your local waste disposal authority for advice or pass to a licensed disposal company.
Transport Information
UN numbers, shipping names, transport classes, and regulatory requirements
Transport of this product can be carried out at ambient temperature but in the event of delays store at 2 – 8°C with all reagents contained within the packaging provided.
Transport of this product can be carried out at ambient temperature but in the event of delays store at 2 – 8°C with all reagents contained within the packaging provided.
Transport of this product can be carried out at ambient temperature but in the event of delays store at 2 – 8°C with all reagents contained within the packaging provided.
Regulatory Information
Chemical regulations, safety assessments, and compliance status
Not applicable.
Frequently Asked Questions
Common questions about safety, handling, and properties
What is the hazard signal word for ElisaRSR™ ZnT8 Ab™?
The signal word is danger.
What is the solubility of ElisaRSR™ ZnT8 Ab™?
In water
What is ElisaRSR™ ZnT8 Ab™ used for?
Quantitative determination of autoantibodies to ZnT8 in human serum
What are the hazard statements for ElisaRSR™ ZnT8 Ab™?
This substance has 2 hazard statements:
- H317: May cause an allergic skin reaction
- H360D: May damage the unborn child