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Safety Data Sheet EN

4-Nitrophenol

CAS 100-02-7

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01

Identification

Product identifiers, regulatory numbers, and supplier information

Product Information

Product Name
4-Nitrophenol
Product Code
241326
Chemical Name
4-Nitrophenol

Regulatory Identifiers

CAS Number
100-02-7 Check regulations →

Identified Uses

Laboratory chemicals, Manufacture of substances

Manufacturers & Suppliers

S

Sigma-Aldrich Chemie GmbH

manufacturer

Eschenstrasse 5, D-82024 TAUFKIRCHEN

+49 (0)89 6513-1130

Emergency Contacts

CHEMTREC Deutschland

0800 181 7059

CHEMTREC weltweit

+49 (0)696 43508409

02

Hazard Identification

GHS classification, signal word, pictograms, and hazard statements

Classified warning

Hazard Classifications

Acute Tox. Cat. 4 H302
Acute Tox. Cat. 4 H332
Acute Tox. Cat. 4 H312
STOT RE Cat. 2 H373

GHS Pictograms

GHS07 - Health hazard

GHS07

GHS08 - Serious health hazard

GHS08

Hazard Statements

H302 + H312 + H332 Harmful if swallowed, in contact with skin or if inhaled.
H373 May cause damage to organs through prolonged or repeated exposure.

Precautionary Statements

P260 Do not breathe dust.
P280 Wear protective gloves/ protective clothing.
P301 + P312 IF SWALLOWED: Call a POISON CENTER/ doctor if you feel unwell.
P314 Get medical advice/ attention if you feel unwell.
IF ON SKIN: Wash with plenty of water. Call a POISON CENTER/ doctor if you feel unwell.
IF INHALED: Remove person to fresh air and keep comfortable for breathing. Call a POISON CENTER/ doctor if you feel unwell.

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03

Composition / Information on Ingredients

Chemical components, concentration ranges, and hazardous substance identification

Type substance
Chemical Name CAS Number Concentration Hazardous
4-Nitrophenol EC: 202-811-7 100-02-7 100% Yes
04

First Aid Measures

Emergency procedures for chemical exposure incidents

Inhalation

Fresh air. Immediately call in physician. If breathing stops: immediately apply artificial respiration, if necessary also oxygen.

Skin contact

Take off immediately all contaminated clothing. Rinse skin with water/ shower. Consult a physician.

Eye contact

Rinse out with plenty of water. Call in ophthalmologist. Remove contact lenses.

Ingestion

Immediately make victim drink water (two glasses at most). Consult a physician.

Immediate Medical Attention

Immediately call in physician.

05

Firefighting Measures

Extinguishing media, specific hazards, and firefighter protection

Suitable media

Water, Foam, Carbon dioxide (CO2), Dry powder

Unsuitable media

For this substance/mixture no limitations of extinguishing agents are given.

Specific hazards

Carbon oxides, Nitrogen oxides (NOx). Combustible. Vapors are heavier than air and may spread along floors. Forms explosive mixtures with air on intense heating. Development of hazardous combustion gases or vapours possible in the event of fire.

Instructions

Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.

Firefighter Protection

Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.

06

Accidental Release Measures

Spill cleanup procedures, containment, and environmental protection

Emergency procedures

Avoid inhalation of dusts. Avoid substance contact. Ensure adequate ventilation. Evacuate the danger area, observe emergency procedures, consult an expert.

Environmental

Do not let product enter drains.

Cleanup methods

Take up dry. Clean up affected area.

—

Related Products

Similar products with comparable safety profiles

07

Handling and Storage

Safe handling precautions, storage conditions, and workplace requirements

Handling

Work under hood. Do not inhale substance/mixture.

Storage

Tightly closed. Dry. Keep in a well-ventilated place. Keep locked up or in an area accessible only to qualified or authorized persons.

Hygiene

Immediately change contaminated clothing. Apply preventive skin protection. Wash hands and face after working with substance.

08

Exposure Controls / PPE

Occupational exposure limits, engineering controls, and protective equipment

Hands

Full contact: Material: Nitrile rubber, Minimum layer thickness: 0,11 mm, Break through time: 480 min, Material tested: KCL 741 Dermatril® L. Splash contact: Material: Nitrile rubber, Minimum layer thickness: 0,11 mm, Break through time: 480 min, Material tested: KCL 741 Dermatril® L. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN374 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell, Internet: www.kcl.de).

Eyes

Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Safety glasses

Respiratory

required when dusts are generated. Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system. Recommended Filter type: Filter type P2. The entrepreneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer. These measures have to be properly documented.

Skin/Body

protective clothing

Environmental

Do not let product enter drains.

09

Physical and Chemical Properties

Appearance, physical state, melting point, boiling point, and material characteristics

Language Code
---
Physical State
solid
Physical State Data
solid
State Under Standard Conditions
---
Appearance
---
Colour
yellow
Colour Intensity
---
Form
---
Odor
characteristic
Odor Threshold
---
Ph
4,4 at 5 g/l at 24 °C
Melting Point
110 - 115 °C - lit.
Boiling Point
279 °C - lit.
Flash Point
169 °C
Freezing Point
---
Softening Point
---
Solidification Point
---
Cloud Point
---
Crystallisation Point
---
Relative Evaporation Rate
---
Evaporation Rate
---
Vapor Pressure
---
Vapor Density
---
Relative Density
---
Bulk Density
---
Density
1,48 g/cm3 at 20 °C
Flammability
---
Upper Explosive Limit
---
Lower Explosive Limit
---
Explosive Limits
---
Auto Ignition Temperature
---
Decomposition Temperature
> 280 °C
Solubility
---
Partition Coefficient
log Pow: 1,95 - Bioaccumulation is not expected.
Solubility In Water
14,8 g/l at 25 °C
Solubility In Fat
---
Molecular Weight
---
Voc Content
---
Metal Corrosion
---
Dynamic Viscosity
No data available
Kinematic Viscosity
No data available
Properties Status
---
10

Stability and Reactivity

Chemical stability, hazardous reactions, and incompatible materials

Stability

The product is chemically stable under standard ambient conditions (room temperature).

Reactivity

Forms explosive mixtures with air on intense heating. A range from approx. 15 Kelvin below the flash point is to be rated as critical. The following applies in general to flammable organic substances and mixtures: in correspondingly fine distribution, when whirled up a dust explosion potential may generally be assumed.

Hazardous reactions

Risk of explosion with: Reducing agents, conc. sulfuric acid. Risk of ignition or formation of inflammable gases or vapours with: alkalines, alkali hydroxides

Avoid

Strong heating.

Incompatible

No data available

Decomposition

In the event of fire: see section 5

12

Ecological Information

Environmental toxicity, biodegradation, and bioaccumulation data

12.1 Toxicity

No data available

12.1 Toxicity

Toxicity to daphnia and other aquatic invertebrates EC50 - Daphnia magna (Water flea) - 22 mg/l - 48 h (OECD Test Guideline 202) Toxicity to algae EC50 - Desmodesmus subspicatus (green algae) - 23,7 mg/l - 96 h Toxicity to bacteria EC5 - Pseudomonas putida - 0,9 mg/l - 16 h Remarks: (IUCLID) Toxicity to fish (Chronic toxicity) Remarks: No data available (4-Nitrophenol)

12.2 Persistence and degradability

Biodegradability Result: 97 % - Readily biodegradable. (OECD Test Guideline 301A)

12.3 Bioaccumulative potential

12.3 Bioaccumulative potential

Bioaccumulation Pimephales promelas (fathead minnow) - 28 d - 0,0441 mg/l (4-Nitrophenol) Bioconcentration factor (BCF): 280

12.4 Mobility in soil

No data available

12.5 Results of PBT and vPvB assessment

This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.

The substance/mixture does not contain components considered to be PBT or vPvB at levels of 0.1% or higher.

12.6 Endocrine disrupting properties

Assessment: The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher.

The substance/mixture does not contain components considered to have endocrine disrupting properties at levels of 0.1% or higher.

12.7 Other adverse effects

Do not empty into drains.
13

Disposal Considerations

Waste treatment methods, disposal recommendations, and waste codes

Treatment

No data available

14

Transport Information

UN numbers, shipping names, transport classes, and regulatory requirements

UN Number
1663
Shipping Name
NITROPHENOLS
Transport Class
6.1
Packing Group
III
15

Regulatory Information

Chemical regulations, safety assessments, and compliance status

This material safety data sheet complies with the requirements of Regulation (EC) No. 1907/2006.

Chemical Safety Assessment Not performed
?

Frequently Asked Questions

Common questions about safety, handling, and properties

What is the hazard signal word for 4-Nitrophenol?

The signal word is warning.

What is the physical form of 4-Nitrophenol?

4-Nitrophenol is a solid with yellow color. It has characteristic odor.

What is 4-Nitrophenol used for?

Laboratory chemicals, Manufacture of substances

What are the hazard statements for 4-Nitrophenol?

This substance has 2 hazard statements:

  • H302 + H312 + H332: Harmful if swallowed, in contact with skin or if inhaled.
  • H373: May cause damage to organs through prolonged or repeated exposure.

What is the melting point of 4-Nitrophenol?

The melting point is 110 - 115 °C - lit. and the boiling point is 279 °C - lit..