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Chemical Substance

4,4'-methylenediphenyl diisocyanate

SDS management

Is 4,4'-methylenediphenyl diisocyanate in your SDS library?

NextSDS finds every safety data sheet that contains 4,4'-methylenediphenyl diisocyanate, flags new hazard classifications and keeps your whole SDS library current for every site.

On 2 regulatory lists. Get alerted when that changes.

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GHS Hazard Pictograms

GHS08 Hazard PictogramGHS08
GHS07 Hazard PictogramGHS07

Hazard Classifications

Skin Irrit. 2
Skin irritation
Warning
Hazard CodeH315
CategorySkin Irrit. 2
Source: Harmonised C&L
Eye Irrit. 2
Eye irritation
Warning
Hazard CodeH319
CategoryEye Irrit. 2
Source: Harmonised C&L
Skin Sens. 1
Skin sensitisation
Warning
Hazard CodeH317
CategorySkin Sens. 1
Source: Harmonised C&L
Acute Tox. 4
Acute toxicity (oral + dermal + inhalation)
Warning
Hazard CodeH302 + H312 + H332
CategoryAcute Tox. 4
Source: Harmonised C&L
STOT SE 3
Specific target organ toxicity — single exposure
Warning
Hazard CodeH336
CategorySTOT SE 3
Source: Harmonised C&L
Resp. Sens. 1
Sensitization, respiratory
Danger
Hazard CodeH334
CategoryResp. Sens. 1
Source: Harmonised C&L
Carc. 2
Carcinogenicity
Warning
Hazard CodeH351
CategoryCarc. 2
Source: Harmonised C&L
STOT RE 2
Specific target organ toxicity — repeated exposure
Warning
Hazard CodeH373
CategorySTOT RE 2
Source: Harmonised C&L
Skin Irrit. 2
Skin irritation
Warning
Hazard CodeH315
CategorySkin Irrit. 2
Source: Harmonised C&L
Eye Irrit. 2
Eye irritation
Warning
Hazard CodeH319
CategoryEye Irrit. 2
Source: Harmonised C&L
Skin Sens. 1
Skin sensitisation
Warning
Hazard CodeH317
CategorySkin Sens. 1
Source: Harmonised C&L
Acute Tox. 4
Acute toxicity (oral + dermal + inhalation)
Warning
Hazard CodeH302 + H312 + H332
CategoryAcute Tox. 4
Source: Harmonised C&L
STOT SE 3
Specific target organ toxicity — single exposure
Warning
Hazard CodeH336
CategorySTOT SE 3
Source: Harmonised C&L
Resp. Sens. 1
Sensitization, respiratory
Danger
Hazard CodeH334
CategoryResp. Sens. 1
Source: Harmonised C&L
Carc. 2
Carcinogenicity
Warning
Hazard CodeH351
CategoryCarc. 2
Source: Harmonised C&L
STOT RE 2
Specific target organ toxicity — repeated exposure
Warning
Hazard CodeH373
CategorySTOT RE 2
Source: Harmonised C&L

Regulatory Lists (2)

CLP ANNEX VI — HARMONISED CLASSIFICATION AND LABELLING
Substances with a harmonised classification and labelling in Annex VI of the CLP Regulation (EC) No 1272/2008. The classification is legally binding across the EU and overrides a supplier's own self-classification.
REACH ANNEX XVII — RESTRICTED SUBSTANCES
Substances restricted under Annex XVII of REACH (EC) No 1907/2006. Superset of the Annex XVII appendix lists: every substance in an appendix group is also a member here, plus the entries restricted outside the CMR appendices.

Related Substances

4,4'-methylenediphenyl diisocyanate, diphenylmethane-4,4'diisocyanate
(Bibenzyl-4,4'-diyl)diisocyanate
1034-24-8
4,4'-diphenylmethane diisocyanate (MDI)
Diphenylmethane-2,4'-diisocyanate
2,4-diisocyanato-1-methylcyclohexane
10581-16-5

Disclaimer

The substance data provided is sourced from various third-party databases and regulatory sources. While we strive to maintain accuracy, we cannot guarantee the completeness, accuracy, or timeliness of this information. Users are responsible for verifying all data before use in compliance, safety, or regulatory contexts. NextSDS is not liable for any decisions made based on this data.