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Chemical Substance

4-methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-{[4-(pyridin-3-yl)pyrimidin-2-yl]amino}benzamide

CAS Number641571-10-0
EC Number700-544-5
Molecular FormulaC28H22F3N7O
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Identifiers

Cas Number641571-10-0Primary
Ec Number700-544-5
Chemical NameNilotinib
Chemical Name4-methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-{[4-(pyridin-3-yl)pyrimidin-2-yl]amino}benzamide

GHS Hazard Pictograms

GHS09 Hazard PictogramGHS09
GHS08 Hazard PictogramGHS08

Hazard Classifications

Repr. 2
Reproductive toxicity
Warning
Hazard CodeH361fd
CategoryRepr. 2
Source: REACH registration C&L
STOT RE 2
Specific target organ toxicity — repeated exposure
Warning
Hazard CodeH373
CategorySTOT RE 2
Source: REACH registration C&L
Aquatic Acute 1
Hazardous to the aquatic environment (acute)
Hazard CodeH400
CategoryAquatic Acute 1
Source: REACH registration C&L
Aquatic Chronic 1
Hazardous to the aquatic environment (long-term)
Hazard CodeH410
CategoryAquatic Chronic 1
Source: REACH registration C&L

Regulatory Lists (2)

RIVM ZZS (ZEER ZORGWEKKENDE STOFFEN)
RIVM ZZS (Zeer Zorgwekkende Stoffen) — Dutch list of Substances of Very High Concern maintained by the National Institute for Public Health and the Environment (RIVM), based on REACH SVHC criteria and CMR/PBT/ED properties
ETUI HAZARDOUS MEDICINAL PRODUCTS (HMP)
ETUI Hazardous Medicinal Products (HMP) — List of hazardous medicinal products identified by the European Trade Union Institute for occupational health protection

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Related Substances

4-Methyl-N-(3-(5-Methyl-1H-iMidazol-1-yl)-5-(trifluoroMethyl)phenyl)-3-((4-(pyridin-3-yl)pyriMidin-2-yl)aMino)benzaMide
641571-15-5
4-Methyl-N-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]benzamide dihydrochloride
1277165-19-1
4-methyl-N-[3-(4-methyl-lH-imidazol-l-yl)-5-(trifluoromethyl)-phenyl]-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]-benzamide fumarate
1304125-88-9
N-(2-Aminophenyl)-4-([[4-(pyridin-3-yl)pyrimidin-2-yl]amino]methyl)benzamide
726169-73-9
4-Chloromethyl-N-[4-methyl-3-[[4-(pyridin-3-yl)pyrimidin-2-yl]amino]phenyl]benzamide
404844-11-7

Disclaimer

The substance data provided is sourced from various third-party databases and regulatory sources. While we strive to maintain accuracy, we cannot guarantee the completeness, accuracy, or timeliness of this information. Users are responsible for verifying all data before use in compliance, safety, or regulatory contexts. NextSDS is not liable for any decisions made based on this data.