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Chemical Substance

methyl (3Z)-3-[({4-[N-methyl-2-(4-methylpiperazin-1-yl)acetamido]phenyl}amino)(phenyl)methylidene]-2-oxo-2,3-dihydro-1H-indole-6-carboxylate

CAS Number656247-17-5
EC Number809-588-0
Molecular FormulaC31H33N5O4
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Identifiers

Cas Number656247-17-5Primary
Ec Number809-588-0
Chemical NameNintedanib
Chemical Namemethyl (3Z)-3-[({4-[N-methyl-2-(4-methylpiperazin-1-yl)acetamido]phenyl}amino)(phenyl)methylidene]-2-oxo-2,3-dihydro-1H-indole-6-carboxylate

GHS Hazard Pictograms

GHS05 Hazard PictogramGHS05
GHS08 Hazard PictogramGHS08
GHS06 Hazard PictogramGHS06

Hazard Classifications

Acute Tox. 3
Acute toxicity (oral + dermal + inhalation)
Danger
Hazard CodeH301 + H311 + H331
CategoryAcute Tox. 3
Source: Notified C&L
Skin Irrit. 2
Skin irritation
Warning
Hazard CodeH315
CategorySkin Irrit. 2
Source: Notified C&L
Eye Dam. 1
Serious eye damage
Danger
Hazard CodeH318
CategoryEye Dam. 1
Source: Notified C&L
Repr. 2
Reproductive toxicity
Warning
Hazard CodeH361fd
CategoryRepr. 2
Source: Notified C&L
STOT RE 1
Specific target organ toxicity — repeated exposure
Danger
Hazard CodeH372
CategorySTOT RE 1
Source: Notified C&L

Related Substances

(3Z)-2,3-Dihydro-3-[[[4-[methyl[2-(4-methyl-1-piperazinyl)acetyl]amino]phenyl]amino]phenylmethylene]-2-oxo-1H-indole-5-carboxylic acid methyl ester
2095596-44-2
(3Z)-2,3-Dihydro-3-[[[4-[methyl[2-(4-methyl-1-piperazinyl)acetyl]amino]phenyl]amino]phenylmethylene]-2-oxo-1H-indole-6-carboxylic acid ethyl ester
1139455-52-9
(3Z)-3-[[[3-[(Dimethylamino)methyl]phenyl]amino]phenylmethylene]-2,3-dihydro-2-oxo-1H-indole-6-carboxamide
334949-59-6
(3Z)-3-[(benzylamino)methylidene]-1-(2,6-dichlorophenyl)indol-2-one
172371-92-5
methyl-1-acetyl-3-(((4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenyl)amino)phenyl)methylene)-2-oxoindoline-6-carboxylate
2130844-77-6

Disclaimer

The substance data provided is sourced from various third-party databases and regulatory sources. While we strive to maintain accuracy, we cannot guarantee the completeness, accuracy, or timeliness of this information. Users are responsible for verifying all data before use in compliance, safety, or regulatory contexts. NextSDS is not liable for any decisions made based on this data.