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Safety Data Sheet EN

4,4'-Methylenebis(phenyl isocyanate)

CAS 101-68-8
EC 202-966-0

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01

Identification

Product identifiers, regulatory numbers, and supplier information

Product Information

Product Name
4,4'-Methylenebis(phenyl isocyanate)
Product Code
36627
Chemical Name
4,4'-methyleendifenyldiisocyanaat

Regulatory Identifiers

CAS Number
101-68-8 Check regulations →
EC Number
202-966-0 Check regulations →

Identified Uses

SU24 Scientific research and development

Manufacturers & Suppliers

Alfa Aesar Thermo Fisher Scientific Chemicals, Inc. logo

Alfa Aesar Thermo Fisher Scientific Chemicals, Inc.

manufacturer

30 Bond Street, Ward Hill, MA 01835-8099

800-343-0660

http://www.alfa.com

Emergency Contacts

Emergency Contact

800-343-0660

Monday-Friday, 8am-7pm EST

02

Hazard Identification

GHS classification, signal word, pictograms, and hazard statements

Classified danger

Hazard Classifications

Acute Tox. Cat. 2 H330
Resp. Sens. Cat. 1 H334
Carc. Cat. 2 H351
STOT RE Cat. 2 H373
Skin Irrit. Cat. 2 H315
Eye Irrit. Cat. 2A H319
Skin Sens. Cat. 1 H317
STOT SE Cat. 3 H335

GHS Pictograms

GHS06 - Acute toxicity

GHS06

GHS08 - Serious health hazard

GHS08

Hazard Statements

H315 Causes skin irritation.
H317 May cause an allergic skin reaction.
H319 Causes serious eye irritation.
H330 Fatal if inhaled.
H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled.
H335 May cause respiratory irritation.
H351 Suspected of causing cancer.
H373 May cause damage to the lung, the blood and the immune system through prolonged or repeated exposure. Route of exposure: Inhalation, Dermal.

Precautionary Statements

P260 Do not breathe dust/fume/gas/mist/vapors/spray.
P280 Wear protective gloves / protective clothing.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P310 Immediately call a POISON CENTER/doctor.

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03

Composition / Information on Ingredients

Chemical components, concentration ranges, and hazardous substance identification

Type substance
Chemical Name CAS Number Concentration Hazardous
4,4'-methyleendifenyldiisocyanaat EC: 202-966-0 101-68-8 --- No
04

First Aid Measures

Emergency procedures for chemical exposure incidents

Inhalation

Supply fresh air. If required, provide artificial respiration. Keep patient warm. Seek immediate medical advice.

Symptoms: Fatal if inhaled. May cause allergy or asthma symptoms or breathing difficulties if inhaled.

Skin contact

Immediately wash with water and soap and rinse thoroughly. Seek immediate medical advice.

Symptoms: Causes skin irritation.

Eye contact

Rinse opened eye for several minutes under running water. Then consult a doctor.

Symptoms: Causes serious eye irritation.

Ingestion

Seek medical treatment.

05

Firefighting Measures

Extinguishing media, specific hazards, and firefighter protection

The data for this section has not been processed yet.

06

Accidental Release Measures

Spill cleanup procedures, containment, and environmental protection

The data for this section has not been processed yet.

Related Products

Similar products with comparable safety profiles

07

Handling and Storage

Safe handling precautions, storage conditions, and workplace requirements

The data for this section has not been processed yet.

08

Exposure Controls / PPE

Occupational exposure limits, engineering controls, and protective equipment

Engineering

Properly operating chemical fume hood designed for hazardous chemicals and having an average face velocity of at least 100 feet per minute.

Hands

Impervious gloves. Check protective gloves prior to each use for their proper condition. The selection of suitable gloves not only depends on the material, but also on quality. Quality will vary from manufacturer to manufacturer. Penetration time of glove material (in minutes) Not determined

Eyes

Safety glasses with side shields / NIOSH (US) or EN 166(EU)

Respiratory

Use self-contained respiratory protective device in emergency situations. Recommended filter device for short term use: Use a respirator with type P100 (USA) or P3 (EN 143) cartridges as a backup to engineering controls. Risk assessment should be performed to determine if air-purifying respirators are appropriate. 'Only use equipment tested and approved under appropriate government standards.

Skin/Body

Protective work clothing.

09

Physical and Chemical Properties

Appearance, physical state, melting point, boiling point, and material characteristics

Physical State
---
Physical State Data
---
State Under Standard Conditions
---
Appearance
Crystalline
Colour
---
Colour Intensity
---
Form
---
Odor
Weak, characteristic
Odor Threshold
Not determined.
Ph
Not applicable.
Melting Point
41-44 ℃ (106-111 ºF)
Boiling Point
194 ℃ (381 ºF)
Flash Point
196 °C (385 ºF)
Freezing Point
---
Softening Point
---
Solidification Point
---
Cloud Point
---
Crystallisation Point
---
Relative Evaporation Rate
---
Evaporation Rate
Not applicable.
Vapor Pressure
0.066 hPa
Vapor Density
Not applicable.
Relative Density
Not determined.
Bulk Density
---
Density
1.239 g/cm3 (10.339 lbs/gal)
Flammability
Not determined.
Upper Explosive Limit
Not determined
Lower Explosive Limit
0.4 Vol %
Explosive Limits
---
Auto Ignition Temperature
>600 °℃ (>1112 ºF)
Decomposition Temperature
Not determined
Solubility
---
Partition Coefficient
Not determined.
Solubility In Water
2 g/l
Solubility In Fat
---
Molecular Weight
---
Voc Content
---
Metal Corrosion
---
Dynamic Viscosity
5 mPas
Kinematic Viscosity
Not applicable.
Properties Status
---
10

Stability and Reactivity

Chemical stability, hazardous reactions, and incompatible materials

The data for this section has not been processed yet.

12

Ecological Information

Environmental toxicity, biodegradation, and bioaccumulation data

The data for this section has not been processed yet.

13

Disposal Considerations

Waste treatment methods, disposal recommendations, and waste codes

The data for this section has not been processed yet.

14

Transport Information

UN numbers, shipping names, transport classes, and regulatory requirements

UN Number
UN2811
Shipping Name
Toxic solids, organic, n.o.s. (4,4'-Methylenebis(phenyl isocyanate))
Transport Class
6.1
Packing Group
III
ADR

Warning: Toxic substances F-A,S-Ã A

IMDG

Warning: Toxic substances F-A,S-Ã A

IATA

Warning: Toxic substances F-A,S-Ã A

15

Regulatory Information

Chemical regulations, safety assessments, and compliance status

The data for this section has not been processed yet.

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Frequently Asked Questions

Common questions about safety, handling, and properties

What is the hazard signal word for 4,4'-Methylenebis(phenyl isocyanate)?

The signal word is danger.

What is 4,4'-Methylenebis(phenyl isocyanate) used for?

SU24 Scientific research and development

What are the hazard statements for 4,4'-Methylenebis(phenyl isocyanate)?

This substance has 8 hazard statements:

  • H315: Causes skin irritation.
  • H317: May cause an allergic skin reaction.
  • H319: Causes serious eye irritation.
  • H330: Fatal if inhaled.
  • H334: May cause allergy or asthma symptoms or breathing difficulties if inhaled.
  • H335: May cause respiratory irritation.
  • H351: Suspected of causing cancer.
  • H373: May cause damage to the lung, the blood and the immune system through prolonged or repeated exposure. Route of exposure: Inhalation, Dermal.

What is the melting point of 4,4'-Methylenebis(phenyl isocyanate)?

The melting point is 41-44 ℃ (106-111 ºF) and the boiling point is 194 ℃ (381 ºF).

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