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4,

4,4'-Methylenebis(phenyl isocyanate)

DANGER SDS/MSDS

Chemical Product Identification & Regulatory Data

Official chemical identifiers, CAS numbers, and regulatory compliance information

Basic Product Information

Product Name
4,4'-Methylenebis(phenyl isocyanate)
Product Code
36627
Chemical Name
4,4'-methyleendifenyldiisocyanaat

Regulatory Identifiers

CAS Number

Chemical Abstracts Service registry number - unique identifier for chemical substances

EC Number

European Community number - used for regulatory compliance in EU/EEA

Uses Information

Identified Uses
SU24 Scientific research and development

Overview

4,4'-Methylenebis(phenyl isocyanate) (CAS: 101-68-8 ) is a crystalline substance commonly used su24 scientific research and development.

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GHS Hazard Classification & Safety Warnings

Globally Harmonized System (GHS) hazard pictograms, signal words, and safety classifications

Classification Status

Classified

Signal Word

danger (Danger)

Hazard Classifications

Acute Tox. Category 2 H330
Resp. Sens. Category 1 H334
Carc. Category 2 H351
STOT RE Category 2 H373
Skin Irrit. Category 2 H315
Eye Irrit. Category 2A H319
Skin Sens. Category 1 H317
STOT SE Category 3 H335

GHS Hazard Pictograms & Safety Symbols

GHS06 GHS Hazard Pictogram: Acute toxicity hazard - Poisonous materials that can cause death or serious harm

GHS06

GHS08 GHS Hazard Pictogram: Serious health hazard - Carcinogenic, mutagenic, or toxic to organs

GHS08

GHS (Globally Harmonized System) pictograms indicate specific chemical hazard categories and safety precautions

Hazard Statements

  • H315: Causes skin irritation.
  • H317: May cause an allergic skin reaction.
  • H319: Causes serious eye irritation.
  • H330: Fatal if inhaled.
  • H334: May cause allergy or asthma symptoms or breathing difficulties if inhaled.
  • H335: May cause respiratory irritation.
  • H351: Suspected of causing cancer.
  • H373: May cause damage to the lung, the blood and the immune system through prolonged or repeated exposure. Route of exposure: Inhalation, Dermal.

Precautionary Statements

  • P260: Do not breathe dust/fume/gas/mist/vapors/spray.
  • P280: Wear protective gloves / protective clothing.
  • P304+P340: IF INHALED: Remove person to fresh air and keep comfortable for breathing.
  • P310: Immediately call a POISON CENTER/doctor.

Chemical Manufacturers & Supply Chain

Authorized suppliers, manufacturers, and distribution network information

Alfa Aesar Thermo Fisher Scientific Chemicals, Inc. company logo - Safety Data Sheet supplier organization

Alfa Aesar Thermo Fisher Scientific Chemicals, Inc.

manufacturer

📍

30 Bond Street, Ward Hill, MA 01835-8099

🌍

US

📞

800-343-0660

📠

800-322-4757

24/7 Emergency Response & Poison Control

Critical emergency contact numbers for chemical spills, exposure incidents, and medical emergencies

Emergency Contact

📞

800-343-0660

🕒

Monday-Friday, 8am-7pm EST

💡

After normal business hours, call Carechem

Chemical Composition & Hazardous Ingredients

Detailed component analysis, concentration ranges, and hazardous substance identification

Product Type

substance

Chemical Components & Hazardous Substances

Chemical Name CAS Number Concentration Hazardous
4,4'-methyleendifenyldiisocyanaat
EC: 202-966-0
101-68-8 Not specified ✓ Non-hazardous

Emergency First Aid Measures

Critical first aid procedures for chemical exposure incidents and medical emergencies

🫁 Inhalation Exposure

Supply fresh air. If required, provide artificial respiration. Keep patient warm. Seek immediate medical advice.

Symptoms:

Fatal if inhaled. May cause allergy or asthma symptoms or breathing difficulties if inhaled.

🖐️ Skin Contact

Immediately wash with water and soap and rinse thoroughly. Seek immediate medical advice.

Symptoms:

Causes skin irritation.

👁️ Eye Contact

Rinse opened eye for several minutes under running water. Then consult a doctor.

Symptoms:

Causes serious eye irritation.

🍽️ Ingestion/Swallowing

Seek medical treatment.

Related Chemical Substances & Alternative Products

Similar chemicals with comparable safety profiles and industrial applications

Technical Specifications & Material Properties

Physical state, chemical properties, melting point, boiling point, and material characteristics

📊 Molecular Weight
Not available
🧪 Ph
Not applicable.
🔥 Flash Point
196 °C (385 ºF)
Critical Property
📊 Voc Content
Not available
📊 Relative Evaporation Rate
Not available
📊 Bulk Density
Not available
📊 Partition Coefficient
Not determined.
📊 Odor Threshold
Not determined.
📊 Freezing Point
Not available
📊 Colour Intensity
Not available
📊 State Under Standard Conditions
Not available
📊 Upper Explosive Limit
Not determined
🧪 Physical State
Not available
📊 Vapor Density
Not applicable.
💨 Vapor Pressure
0.066 hPa
👃 Odor
Weak, characteristic
📊 Lower Explosive Limit
0.4 Vol %
📊 Crystallisation Point
Not available
🔥 Flammability
Not determined.
📊 Metal Corrosion
Not available
📊 Softening Point
Not available
📊 Solubility In Fat
Not available
💨 Evaporation Rate
Not applicable.
📊 Cloud Point
Not available
💨 Boiling Point
194 ℃ (381 ºF)
Critical Property
🧊 Melting Point
41-44 ℃ (106-111 ºF)
Critical Property
📊 Dynamic Viscosity
5 mPas
📊 Solubility In Water
2 g/l
⚖️ Density
1.239 g/cm3 (10.339 lbs/gal)
Critical Property
📊 Form
Not available
📊 Physical State Data
Not available
🎨 Colour
Not available
👁️ Appearance
Crystalline
📊 Solidification Point
Not available
💧 Solubility
Not available
📊 Decomposition Temperature
Not determined
📊 Relative Density
Not determined.
📊 Kinematic Viscosity
Not applicable.
📊 Auto Ignition Temperature
>600 °℃ (>1112 ºF)
📊 Properties Status
Not available
📊 Explosive Limits
Not available

Exposure Controls & Personal Protective Equipment (PPE)

Occupational exposure limits, engineering controls, and required safety equipment

🏭 Engineering Controls

Properly operating chemical fume hood designed for hazardous chemicals and having an average face velocity of at least 100 feet per minute.

🧤 Hand Protection

Impervious gloves. Check protective gloves prior to each use for their proper condition. The selection of suitable gloves not only depends on the material, but also on quality. Quality will vary from manufacturer to manufacturer. Penetration time of glove material (in minutes) Not determined

👁️ Eye Protection

Safety glasses with side shields / NIOSH (US) or EN 166(EU)

😷 Respiratory Protection

Use self-contained respiratory protective device in emergency situations. Recommended filter device for short term use: Use a respirator with type P100 (USA) or P3 (EN 143) cartridges as a backup to engineering controls. Risk assessment should be performed to determine if air-purifying respirators are appropriate. 'Only use equipment tested and approved under appropriate government standards.

🦺 Skin/Body Protection

Protective work clothing.

Transportation & Shipping Information

UN numbers, shipping names, transport classes, and regulatory transport requirements

🏷️ UN Number

UN2811

📦 Proper Shipping Name

Toxic solids, organic, n.o.s. (4,4'-Methylenebis(phenyl isocyanate))

⚠️ Transport Hazard Class

6.1

📋 Packing Group

III

🚛 ADR Transport Precautions

Warning: Toxic substances F-A,S-Ã A

🚢 IMDG Maritime Transport Precautions

Warning: Toxic substances F-A,S-Ã A

✈️ IATA Air Transport Precautions

Warning: Toxic substances F-A,S-Ã A

Chemical Safety FAQ & Common Questions

Most frequently asked questions about safety, handling, storage, and regulatory compliance

What is the hazard signal word for 4,4'-Methylenebis(phenyl isocyanate)?

The signal word for this substance is "danger".

What is 4,4'-Methylenebis(phenyl isocyanate) used for?

SU24 Scientific research and development

What are the hazard statements for 4,4'-Methylenebis(phenyl isocyanate)?

This substance has 8 hazard statements: H315: Causes skin irritation. H317: May cause an allergic skin reaction. H319: Causes serious eye irritation. H330: Fatal if inhaled. H334: May cause allergy or asthma symptoms or breathing difficulties if inhaled. H335: May cause respiratory irritation. H351: Suspected of causing cancer. H373: May cause damage to the lung, the blood and the immune system through prolonged or repeated exposure. Route of exposure: Inhalation, Dermal.

What is the melting point of 4,4'-Methylenebis(phenyl isocyanate)?

The melting point is 41-44 ℃ (106-111 ºF) and the boiling point is 194 ℃ (381 ºF).