NextSDS Logo
Chemical Substance

4,4' -Methylenediphenyl diisocyanate

CAS Number101-68-8
EC Number202-966-0
Screen your chemical compliance

Free 10-second scan. Upload a document and check compliance instantly.

Scan Now

Identifiers

Cas Number101-68-8Primary
Chemical Name4,4' -Methylenediphenyl diisocyanate
Ec Number202-966-0
Chemical Name4,4'-Diphenylmethane diisocyanate
Chemical Name4,4'-methylenediphenyl diisocyanate diphenylmethane-4,4'-diisocyanate 615-005-00-9
Chemical Name4,4'-methyleendifenyldiisocyanaat
Chemical Name4,4'-methylenediphenyl diisocyanate
Chemical NameDifenylmethaan-di-isocyanaat
Reach Registration01-2119457014-47

GHS Hazard Pictograms

GHS07 Hazard PictogramGHS07
GHS08 Hazard PictogramGHS08

Hazard Classifications

Skin Irrit. 2
Skin irritation
Warning
Hazard CodeH315
CategorySkin Irrit. 2
Source: Harmonised C&L
Eye Irrit. 2
Eye irritation
Warning
Hazard CodeH319
CategoryEye Irrit. 2
Source: Harmonised C&L
Skin Sens. 1
Skin sensitisation
Warning
Hazard CodeH317
CategorySkin Sens. 1
Source: Harmonised C&L
Acute Tox. 4
Acute toxicity (oral + dermal + inhalation)
Warning
Hazard CodeH302 + H312 + H332
CategoryAcute Tox. 4
Source: Harmonised C&L
STOT SE 3
Specific target organ toxicity — single exposure
Warning
Hazard CodeH336
CategorySTOT SE 3
Source: Harmonised C&L
Resp. Sens. 1
Sensitization, respiratory
Danger
Hazard CodeH334
CategoryResp. Sens. 1
Source: Harmonised C&L
Carc. 2
Carcinogenicity
Warning
Hazard CodeH351
CategoryCarc. 2
Source: Harmonised C&L
STOT RE 2
Specific target organ toxicity — repeated exposure
Warning
Hazard CodeH373
CategorySTOT RE 2
Source: Harmonised C&L

Regulatory Lists (9)

IFA GESTIS INTERNATIONAL LIMIT VALUES
IFA GESTIS International Limit Values (ILV) — Occupational exposure limits for chemical agents in the workplace, maintained by the Institut für Arbeitsschutz der DGUV (Germany)
REACH ANNEX XVII ENTRY 74 — DIISOCYANATES
REACH Annex XVII Restriction Entry 74 — Diisocyanates restricted under Regulation (EU) 2020/1149 amending REACH, requiring training for industrial and professional use of substances containing diisocyanates at concentration >= 0.1% by weight
BLUESIGN SYSTEM SUBSTANCES LIST
Bluesign System Substances List — Substances restricted or banned under the Bluesign chemical management system for sustainable textile production
VOLVO GREY LIST
Volvo Grey List — Substances subject to restricted use in Volvo vehicles, targeted for phase-out
GERMAN FEDERAL ENVIRONMENT AGENCY (UBA)
German Federal Environment Agency (UBA) — Substances identified by the Umweltbundesamt as environmentally hazardous or requiring regulatory action
KEMI PRIO PHASE-OUT SUBSTANCES
KEMI PRIO Phase-Out Substances — Swedish Chemicals Agency list of substances with properties of very high concern that should be phased out
TRADE UNION PRIORITY LIST
Trade Union Priority List — Substances prioritised by European trade unions for workplace exposure reduction and substitution
PBT/VPVB ASSESSMENT
ECHA PBT/vPvB assessment — Substances evaluated for Persistent, Bioaccumulative and Toxic or very Persistent and very Bioaccumulative properties under REACH
EU COSMETIC PRODUCTS REGULATION: PROHIBITED SUBSTANCES
EU Cosmetic Products Regulation: Prohibited Substances — Substances prohibited in cosmetic products under Annex II of Regulation (EC) No 1223/2009

Manage Your Chemicals

Track substances, monitor regulatory changes, and stay compliant.

Try NextSDS Free

Related Substances

(Bibenzyl-4,4'-diyl)diisocyanate
1034-24-8
2,4-diisocyanato-1-methylcyclohexane
10581-16-5
4,4'-Biphenyldiisocyanate
2761-22-0
4,4'-Methylenediphenyl diisocyanate, oligomers
25686-28-6
2,4-dimethyloctane-1,8-diyl diisocyanate
68882-56-4

Disclaimer

The substance data provided is sourced from various third-party databases and regulatory sources. While we strive to maintain accuracy, we cannot guarantee the completeness, accuracy, or timeliness of this information. Users are responsible for verifying all data before use in compliance, safety, or regulatory contexts. NextSDS is not liable for any decisions made based on this data.