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Safety Data Sheet EN

Clonidine (hydrochloride)

CAS 4205-91-8
EC 224-121-5

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01

Identification

Product identifiers, regulatory numbers, and supplier information

Product Information

Product Name
Clonidine (hydrochloride)
Product Code
15949
Synonyms
N-(2,6-dichlorophenyl)-4,5-dihydro-1H-imidazol-2-amine, monohydrochloride; ST 155

Regulatory Identifiers

CAS Number
4205-91-8 Check regulations →
EC Number
224-121-5 Check regulations →

Identified Uses

This product is for research use - Not for human or veterinary diagnostic or therapeutic use.

Manufacturers & Suppliers

C

Cayman Chemical Co.

manufacturer

1180 E. Ellsworth Rd., Ann Arbor, MI 48108, USA

Emergency Contacts

Emergency Contact

+1 (734) 971-3335

During normal opening times

Emergency Contact

800-424-9300

Emergency Contact

703-741-5970

02

Hazard Identification

GHS classification, signal word, pictograms, and hazard statements

Classified danger

Hazard Classifications

Acute Tox. Cat. 3
Acute Tox. Cat. 3
Acute Tox. Cat. 1
STOT SE Cat. 1 H370
Aquatic Chronic Cat. 1 H410

GHS Pictograms

GHS06 - Acute toxicity

GHS06

GHS08 - Serious health hazard

GHS08

GHS09 - Environmental hazard

GHS09

Hazard Statements

H301 + H311 Toxic if swallowed or in contact with skin.
H330 Fatal if inhaled.
H370 Causes damage to organs.
H410 Very toxic to aquatic life with long lasting effects.

Precautionary Statements

P260 Do not breathe dust/fume/gas/mist/vapors/spray.
P264 Wash thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P273 Avoid release to the environment.
P280 Wear protective gloves / protective clothing.
P284 [In case of inadequate ventilation] wear respiratory protection.
P301 + P310 If swallowed: Immediately call a poison center/doctor.
P302 + P352 If on skin: Wash with plenty of water.
P304 + P340 If inhaled: Remove person to fresh air and keep comfortable for breathing.
P308 + P311 IF exposed or concerned: Call a poison center/doctor.
P312 Call a poison center/doctor if you feel unwell.
P320 Specific treatment is urgent (see on this label).
P330 Rinse mouth.
P361 + P364 Take off immediately all contaminated clothing and wash it before reuse.
P391 Collect spillage.
P403 + P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container in accordance with local/regional/national/international regulations.

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03

Composition / Information on Ingredients

Chemical components, concentration ranges, and hazardous substance identification

Type substance

Chemical characterization: Substances

Chemical Name CAS Number Concentration Hazardous
Clonidine (hydrochloride) EC: 224-121-5 4205-91-8 --- No
04

First Aid Measures

Emergency procedures for chemical exposure incidents

Inhalation

Supply fresh air or oxygen; call for doctor. In case of unconsciousness place patient stably in side position for transportation.

Skin contact

Immediately wash with water and soap and rinse thoroughly.

Eye contact

Rinse opened eye for several minutes under running water. Then consult a doctor.

Ingestion

Do not induce vomiting; immediately call for medical help.

05

Firefighting Measures

Extinguishing media, specific hazards, and firefighter protection

Suitable media

Use fire fighting measures that suit the environment.

Unsuitable media

A solid water stream may be inefficient.

Specific hazards

No further relevant information available.

Firefighter Protection

Mouth respiratory protective device.

06

Accidental Release Measures

Spill cleanup procedures, containment, and environmental protection

Environmental

Inform respective authorities in case of seepage into water course or sewage system.

Related Products

Similar products with comparable safety profiles

07

Handling and Storage

Safe handling precautions, storage conditions, and workplace requirements

Handling

Thorough dedusting. Open and handle receptacle with care.

Storage

Store in accordance with information listed on the product insert. Keep receptacle tightly sealed.

Fire prevention

Keep respiratory protective device available.

08

Exposure Controls / PPE

Occupational exposure limits, engineering controls, and protective equipment

Engineering

No further data; see section 7.

Hands

Protective gloves. The glove material has to be impermeable and resistant to the product/ the substance/ the preparation. Due to missing tests no recommendation to the glove material can be given for the product/ the preparation/ the chemical mixture. Selection of the glove material on consideration of the penetration times, rates of diffusion and the degradation. The selection of the suitable gloves does not only depend on the material, but also on further marks of quality and varies from manufacturer to manufacturer. The exact break through time has to be found out by the manufacturer of the protective gloves and has to be observed.

Eyes

Not required.

Respiratory

In case of brief exposure or low pollution use respiratory filter device. In case of intensive or longer exposure use respiratory protective device that is independent of circulating air.

09

Physical and Chemical Properties

Appearance, physical state, melting point, boiling point, and material characteristics

Metal Corrosion
---
Solubility In Fat
---
Melting Point
Undetermined.
Appearance
---
Solidification Point
---
Voc Content
---
Crystallisation Point
---
State Under Standard Conditions
---
Softening Point
---
Decomposition Temperature
Not determined.
Colour Intensity
---
Freezing Point
---
Upper Explosive Limit
Not determined.
Physical State
Solid
Dynamic Viscosity
Not applicable.
Partition Coefficient
Not determined.
Relative Evaporation Rate
---
Vapor Pressure
Not applicable.
Auto Ignition Temperature
Not determined.
Flammability
Product is not flammable.
Molecular Weight
266.6 g/mol
Physical State Data
solid
Odor Threshold
Not determined.
Explosive Limits
---
Ph
Not applicable.
Boiling Point
Undetermined.
Vapor Density
Not applicable.
Odor
Characteristic
Relative Density
Not determined.
Flash Point
Not applicable.
Form
Solid
Colour
Not determined.
Density
Not determined.
Solubility
DMF: 0.3 mg/ml; DMSO: 3 mg/ml; Ethanol: 2 mg/ml; PBS (pH 7.2): 5 mg/ml
Solubility In Water
Not determined.
Evaporation Rate
Not applicable.
Cloud Point
---
Kinematic Viscosity
Not applicable.
Lower Explosive Limit
Not determined.
Bulk Density
---
Properties Status
---
10

Stability and Reactivity

Chemical stability, hazardous reactions, and incompatible materials

Stability

Stable if used according to specifications.

Reactivity

No further relevant information available.

Hazardous reactions

No dangerous reactions known.

Avoid

No further relevant information available.

Incompatible

strong oxidizing agents

Decomposition

carbon dioxide, carbon monoxide, hydrogen chloride gas, nitrogen oxides

12

Ecological Information

Environmental toxicity, biodegradation, and bioaccumulation data

The data for this section has not been processed yet.

13

Disposal Considerations

Waste treatment methods, disposal recommendations, and waste codes

Treatment

Must not be disposed of together with household garbage. Do not allow product to reach sewage system.

Disposal

Must not be disposed of together with household garbage. Do not allow product to reach sewage system.

14

Transport Information

UN numbers, shipping names, transport classes, and regulatory requirements

UN Number
2811
Shipping Name
TOXIC SOLID, ORGANIC, N.O.S. (CLONIDINE (HYDROCHLORIDE))
Transport Class
6.1
Packing Group
I
ADR

Warning: Toxic substances

IMDG

Warning: Toxic substances

IATA

Warning: Toxic substances

15

Regulatory Information

Chemical regulations, safety assessments, and compliance status

No further relevant information available.

Chemical Safety Assessment Not performed
?

Frequently Asked Questions

Common questions about safety, handling, and properties

What other names is Clonidine (hydrochloride) known by?

Clonidine (hydrochloride) is also known as: N-(2,6-dichlorophenyl)-4,5-dihydro-1H-imidazol-2-amine, monohydrochloride; ST 155

What is the hazard signal word for Clonidine (hydrochloride)?

The signal word is danger.

What is the physical form of Clonidine (hydrochloride)?

Clonidine (hydrochloride) is a solid with not determined. color. It has characteristic odor.

What is the solubility of Clonidine (hydrochloride)?

DMF: 0.3 mg/ml; DMSO: 3 mg/ml; Ethanol: 2 mg/ml; PBS (pH 7.2): 5 mg/ml

What is Clonidine (hydrochloride) used for?

This product is for research use - Not for human or veterinary diagnostic or therapeutic use.

What are the hazard statements for Clonidine (hydrochloride)?

This substance has 4 hazard statements:

  • H301 + H311: Toxic if swallowed or in contact with skin.
  • H330: Fatal if inhaled.
  • H370: Causes damage to organs.
  • H410: Very toxic to aquatic life with long lasting effects.

What is the melting point of Clonidine (hydrochloride)?

The melting point is Undetermined. and the boiling point is Undetermined..