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Safety Data Sheet EN

Doxorubicin (hydrochloride)

CAS 25316-40-9
EC 246-818-3

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01

Identification

Product identifiers, regulatory numbers, and supplier information

Product Information

Product Name
Doxorubicin (hydrochloride)
Product Code
15007
Chemical Name
(8S,10S)-10-[(3-amino-2,3,6-trideoxy--L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy8-(2-hydroxyacetyl)-1-methoxy-5,12-naphthacenedione, monohydrochloride
Synonyms
DOX

Regulatory Identifiers

CAS Number
25316-40-9 Check regulations →
EC Number
246-818-3 Check regulations →

Identified Uses

This product is for research use - Not for human or veterinary diagnostic or therapeutic use.

Manufacturers & Suppliers

C

Cayman Chemical Co.

manufacturer

1180 E. Ellsworth Rd. Ann Arbor, MI 48108 USA

Emergency Contacts

Emergency Contact

+1 (734) 971-3335

During normal opening times

Emergency Contact

800-424-9300

Emergency Contact

703-741-5970

02

Hazard Identification

GHS classification, signal word, pictograms, and hazard statements

Classified danger

Hazard Classifications

Carc. Cat. 1B H350
Acute Tox. Cat. 4 H302

GHS Pictograms

GHS07 - Health hazard

GHS07

GHS08 - Serious health hazard

GHS08

Hazard Statements

H302 Harmful if swallowed.
H350 May cause cancer.

Precautionary Statements

P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P264 Wash thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301 + P312 If swallowed: Call a poison center/doctor if you feel unwell.
P308 + P313 IF exposed or concerned: Get medical advice/attention.
P330 Rinse mouth.
P405 Store locked up.
P501 Dispose of contents/container in accordance with local/regional/national/international regulations.

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03

Composition / Information on Ingredients

Chemical components, concentration ranges, and hazardous substance identification

Type Substances
Chemical Name CAS Number Concentration Hazardous
(8S,10S)-10-[(3-amino-2,3,6-trideoxy--L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy8-(2-hydroxyacetyl)-1-methoxy-5,12-naphthacenedione, monohydrochloride EC: 246-818-3 25316-40-9 --- No
04

First Aid Measures

Emergency procedures for chemical exposure incidents

Inhalation

Supply fresh air; consult doctor in case of complaints.

Eye contact

Rinse opened eye for several minutes under running water.

Ingestion

Immediately call a doctor.

Immediate Medical Attention

No further relevant information available.

Medical Treatment

No further relevant information available.

05

Firefighting Measures

Extinguishing media, specific hazards, and firefighter protection

The data for this section has not been processed yet.

06

Accidental Release Measures

Spill cleanup procedures, containment, and environmental protection

The data for this section has not been processed yet.

Related Products

Similar products with comparable safety profiles

07

Handling and Storage

Safe handling precautions, storage conditions, and workplace requirements

The data for this section has not been processed yet.

08

Exposure Controls / PPE

Occupational exposure limits, engineering controls, and protective equipment

Engineering

No further data; see section 7.

Hands

Protective gloves S_ The glove material has to be impermeable and resistant to the product/ the substance/ the preparation. Due to missing tests no recommendation to the glove material can be given for the product/ the preparation/ the chemical mixture. Selection of the glove material on consideration of the penetration times, rates of diffusion and the degradation Material of gloves The selection of the suitable gloves does not only depend on the material, but also on further marks of quality and varies from manufacturer to manufacturer. Penetration time of glove material The exact break through time has to be found out by the manufacturer of the protective gloves and has to be observed.

Eyes

Tightly sealed goggles R_

Respiratory

In case of brief exposure or low pollution use respiratory filter device. In case of intensive or longer exposure use respiratory protective device that is independent of circulating air.

09

Physical and Chemical Properties

Appearance, physical state, melting point, boiling point, and material characteristics

Density
Not determined.
Auto Ignition Temperature
Not determined.
Solubility In Fat
---
Crystallisation Point
---
Voc Content
---
Appearance
Solid
Properties Status
---
Molecular Weight
580 g/mol
Relative Evaporation Rate
---
Evaporation Rate
Not applicable.
Colour
Not determined.
Solubility
DMSO: 10 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml; Ethanol: 1 mg/ml; PBS (pH 7.2): >100g/ml
Form
Solid
Freezing Point
---
Colour Intensity
---
Bulk Density
---
Softening Point
---
Lower Explosive Limit
Not determined.
Cloud Point
---
Relative Density
Not determined.
Dynamic Viscosity
Not applicable.
Metal Corrosion
---
Solubility In Water
Not determined.
Flammability
Product is not flammable.
Melting Point
Undetermined.
Flash Point
Not applicable.
Explosive Limits
---
Upper Explosive Limit
Not determined.
Partition Coefficient
Not determined.
Physical State
Solid
Odor Threshold
Not determined.
Odor
Characteristic
Vapor Density
Not applicable.
Decomposition Temperature
Not determined.
Kinematic Viscosity
Not applicable.
Boiling Point
Undetermined.
Solidification Point
---
State Under Standard Conditions
---
Physical State Data
solid
Vapor Pressure
Not applicable.
Ph
Not applicable.
10

Stability and Reactivity

Chemical stability, hazardous reactions, and incompatible materials

The data for this section has not been processed yet.

12

Ecological Information

Environmental toxicity, biodegradation, and bioaccumulation data

The data for this section has not been processed yet.

13

Disposal Considerations

Waste treatment methods, disposal recommendations, and waste codes

The data for this section has not been processed yet.

14

Transport Information

UN numbers, shipping names, transport classes, and regulatory requirements

UN Number
not regulated
Shipping Name
not regulated
Transport Class
not regulated
Packing Group
not regulated
15

Regulatory Information

Chemical regulations, safety assessments, and compliance status

The data for this section has not been processed yet.

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Frequently Asked Questions

Common questions about safety, handling, and properties

What other names is Doxorubicin (hydrochloride) known by?

Doxorubicin (hydrochloride) is also known as: DOX

What is the hazard signal word for Doxorubicin (hydrochloride)?

The signal word is danger.

What is the physical form of Doxorubicin (hydrochloride)?

Doxorubicin (hydrochloride) is a solid appearing as solid with not determined. color. It has characteristic odor.

What is the solubility of Doxorubicin (hydrochloride)?

DMSO: 10 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml; Ethanol: 1 mg/ml; PBS (pH 7.2): >100g/ml

What is Doxorubicin (hydrochloride) used for?

This product is for research use - Not for human or veterinary diagnostic or therapeutic use.

What are the hazard statements for Doxorubicin (hydrochloride)?

This substance has 2 hazard statements:

  • H302: Harmful if swallowed.
  • H350: May cause cancer.

What is the melting point of Doxorubicin (hydrochloride)?

The melting point is Undetermined. and the boiling point is Undetermined..

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