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Safety Data Sheet EN

N,N-Dimethylformamide PEPTIPURE® ≥99,8 % for peptide synthesis

CAS 68-12-2
EC 200-679-5

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01

Identification

Product identifiers, regulatory numbers, and supplier information

Product Information

Product Name
N,N-Dimethylformamide PEPTIPURE® ≥99,8 % for peptide synthesis
Product Code
A529
Chemical Name
N,N-Dimethylformamide

Regulatory Identifiers

CAS Number
68-12-2 Check regulations →
EC Number
200-679-5 Check regulations →
REACH No.
01-2119475605-32-xxxx

Identified Uses

laboratory chemical, laboratory and analytical use

Manufacturers & Suppliers

Carl Roth GmbH + Co KG logo

Carl Roth GmbH + Co KG

distributor

Schoemperlenstr. 3-5 D-76185 Karlsruhe Germany

+49 (0) 721 - 56 06 0

www.carlroth.de

Emergency Contacts

Giftzentrale München

+49/(0)89 19240

02

Hazard Identification

GHS classification, signal word, pictograms, and hazard statements

Classified danger

Hazard Classifications

Flam. Liq. Cat. 3 H226
Acute Tox. Cat. 4 H312
Acute Tox. Cat. 4 H332
Eye Irrit. Cat. 2 H319
Repr. Cat. 1B H360D

GHS Pictograms

GHS02 - Flammable

GHS02

GHS07 - Health hazard

GHS07

GHS08 - Serious health hazard

GHS08

Hazard Statements

H226 Flammable liquid and vapour
H312 + H332 Harmful in contact with skin or if inhaled
H319 Causes serious eye irritation
H360D May damage the unborn child

Precautionary Statements

P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302 + P352 IF ON SKIN: Wash with plenty of soap and water.
P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P308 + P313 IF exposed or concerned: Get medical advice/attention.

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03

Composition / Information on Ingredients

Chemical components, concentration ranges, and hazardous substance identification

Type substance
Chemical Name CAS Number Concentration Hazardous
N,N-Dimethylformamide EC: 200-679-5 68-12-2 100% Yes
04

First Aid Measures

Emergency procedures for chemical exposure incidents

Inhalation

Provide fresh air. In all cases of doubt, or when symptoms persist, seek medical advice.

Skin contact

Rinse skin with water/shower.

Eye contact

Irrigate copiously with clean, fresh water for at least 10 minutes, holding the eyelids apart. In case of eye irritation consult an ophthalmologist.

Symptoms: eye irritation

Ingestion

In case of accident or unwellness, seek medical advice immediately (show directions for use or safety data sheet if possible).

05

Firefighting Measures

Extinguishing media, specific hazards, and firefighter protection

Suitable media

Co-ordinate fire-fighting measures to the fire surroundings water spray, foam, dry extinguishing powder, carbon dioxide (CO₂)

Unsuitable media

water jet

Specific hazards

Combustible. Vapours are heavier than air, spread along floors and form explosive mixtures with air. Vapours can form explosive mixtures with air.

Instructions

Fight fire with normal precautions from a reasonable distance.

Firefighter Protection

Wear self-contained breathing apparatus.

06

Accidental Release Measures

Spill cleanup procedures, containment, and environmental protection

Emergency procedures

Wearing of suitable protective equipment (including personal protective equipment referred to under Section 8 of the safety data sheet) to prevent any contamination of skin, eyes and personal clothing. Avoid contact with skin, eyes and clothes. Do not breathe vapour/spray. Avoidance of ignition sources.

Environmental

Keep away from drains, surface and ground water. Explosive properties.

Cleanup methods

Absorb with liquid-binding material

Materials: liquid-binding material (sand, diatomaceous earth, acid- or universal binding agents)

Related Products

Similar products with comparable safety profiles

07

Handling and Storage

Safe handling precautions, storage conditions, and workplace requirements

Handling

Provision of sufficient ventilation. Measures to prevent fire as well as aerosol and dust generation. Keep away from sources of ignition - No smoking. Take precautionary measures against static discharge.

Storage

Keep container tightly closed. Recommended storage temperature: 15 – 25 °C.

Hygiene

Wash hands before breaks and after work. Keep away from food, drink and animal feedingstuffs. When using do not smoke.

Fire prevention

Measures to prevent fire as well as aerosol and dust generation. Keep away from sources of ignition - No smoking. Take precautionary measures against static discharge.

08

Exposure Controls / PPE

Occupational exposure limits, engineering controls, and protective equipment

Hands

Wear suitable gloves. Chemical protection gloves are suitable, which are tested according to EN 374. For special purposes, it is recommended to check the resistance to chemicals of the protective gloves mentioned above together with the supplier of these gloves. The times are approximate values from measurements at 22 °C and permanent contact. Increased temperatures due to heated substances, body heat etc. and a reduction of the effective layer thickness by stretching can lead to a considerable reduction of the breakthrough time. If in doubt, contact manufacturer. At an approx. 1.5 times larger / smaller layer thickness, the respective breakthrough time is doubled / halved. The data apply only to the pure substance. When transferred to substance mixtures, they may only be considered as a guide. Type of material: Butyl caoutchouc (butyl rubber). Material thickness: ≥0,5 mm. Breakthrough times of the glove material: >480 minutes (permeation: level 6).

Eyes

Use safety goggle with side protection.

Respiratory

Respiratory protection necessary at: Aerosol or mist formation. P2 (filters at least 94 % of airborne particles, colour code: White). Type: A (against organic gases and vapours with a boiling point of > 65 °C, colour code: Brown). Observe the wear time limits according GefStoffV in combination with the rules for using respiratory protection apparatus (BGR 190).

Environmental

Keep away from drains, surface and ground water.

09

Physical and Chemical Properties

Appearance, physical state, melting point, boiling point, and material characteristics

Dynamic Viscosity
0.85 mPa s at 20 °C
Explosive Limits
---
Softening Point
---
Flash Point
57.5 °C at 1,013 hPa
Density
0.95 g/cm³ at 20 °C
Decomposition Temperature
>350 °C
Solubility In Water
miscible in any proportion
Relative Density
this information is not available
Physical State
liquid (fluid)
Crystallisation Point
---
Relative Evaporation Rate
---
Flammability
not relevant (fluid)
Colour Intensity
---
Auto Ignition Temperature
435 °C at 1,013 hPa
Cloud Point
---
Evaporation Rate
no data available
Upper Explosive Limit
16 vol% (500 g/m³)
Form
---
Solubility
---
Colour
colourless
Partition Coefficient
-1.01 (TOXNET)
Vapor Pressure
3.77 hPa at 20 °C
Freezing Point
-61 °C
Melting Point
-61 °C
Vapor Density
2.52 (air = 1)
Appearance
liquid (fluid)
Kinematic Viscosity
0.8947 mm²/s at 20 °C
Boiling Point
153 °C at 1,013 hPa
Odor Threshold
0.329 ppm
Solidification Point
---
Physical State Data
liquid
Metal Corrosion
---
Lower Explosive Limit
2.2 vol% (70 g/m³)
Solubility In Fat
---
Bulk Density
Not applicable
State Under Standard Conditions
---
Odor
like: amine
Properties Status
---
Ph
7 (in aqueous solution: 200 g/l, 20 °C)
Voc Content
---
Molecular Weight
---
10

Stability and Reactivity

Chemical stability, hazardous reactions, and incompatible materials

Stability

The material is stable under normal ambient and anticipated storage and handling conditions of temperature and pressure.

Reactivity

Risk of ignition. In case of warming: Vapours can form explosive mixtures with air.

Hazardous reactions

Violent reaction with: Strong oxidiser

Avoid

Keep away from heat. Decomposition takes place from temperatures above: >350 °C.

Incompatible

There is no additional information.

Decomposition

Hazardous combustion products: see section 5. Release of: Formaldehyde. Ammonia (NH3).

12

Ecological Information

Environmental toxicity, biodegradation, and bioaccumulation data

The data for this section has not been processed yet.

13

Disposal Considerations

Waste treatment methods, disposal recommendations, and waste codes

The data for this section has not been processed yet.

14

Transport Information

UN numbers, shipping names, transport classes, and regulatory requirements

UN Number
2265
Shipping Name
N,N-DIMETHYLFORMAMIDE
Transport Class
3 (flammable liquids)
Packing Group
III
ADR

Provisions for dangerous goods (ADR) should be complied within the premises.

15

Regulatory Information

Chemical regulations, safety assessments, and compliance status

The data for this section has not been processed yet.

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Frequently Asked Questions

Common questions about safety, handling, and properties

What is the hazard signal word for N,N-Dimethylformamide PEPTIPURE® ≥99,8 % for peptide synthesis?

The signal word is danger.

What is the physical form of N,N-Dimethylformamide PEPTIPURE® ≥99,8 % for peptide synthesis?

N,N-Dimethylformamide PEPTIPURE® ≥99,8 % for peptide synthesis is a liquid (fluid) appearing as liquid (fluid) with colourless color. It has like: amine odor.

What is N,N-Dimethylformamide PEPTIPURE® ≥99,8 % for peptide synthesis used for?

laboratory chemical, laboratory and analytical use

What are the hazard statements for N,N-Dimethylformamide PEPTIPURE® ≥99,8 % for peptide synthesis?

This substance has 4 hazard statements:

  • H226: Flammable liquid and vapour
  • H312 + H332: Harmful in contact with skin or if inhaled
  • H319: Causes serious eye irritation
  • H360D: May damage the unborn child

What is the melting point of N,N-Dimethylformamide PEPTIPURE® ≥99,8 % for peptide synthesis?

The melting point is -61 °C and the boiling point is 153 °C at 1,013 hPa.

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