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Safety Data Sheet EN

Buspirone hydrochloride

CAS 33386-08-2

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01

Identification

Product identifiers, regulatory numbers, and supplier information

Product Information

Product Name
Buspirone hydrochloride
Product Code
B7148

Regulatory Identifiers

CAS Number
33386-08-2 Check regulations →
REACH No.
A registration number is not available for this substance as the substance or its uses are exempted from registration or the annual tonnage does not require a registration.

Identified Uses

Laboratory chemicals, Manufacture of substances

Manufacturers & Suppliers

S

Sigma

manufacturer

S

Sigma-Aldrich Chemie GmbH

manufacturer

Eschenstrasse 5, D-82024 TAUFKIRCHEN

+49 (0)89 6513-1130

Emergency Contacts

CHEMTREC Deutschland

0800 181 7059

CHEMTREC weltweit

+49 (0)696 43508409

02

Hazard Identification

GHS classification, signal word, pictograms, and hazard statements

Classified danger

Hazard Classifications

Acute Tox. Cat. 3 H301

GHS Pictograms

GHS06 - Acute toxicity

GHS06

Hazard Statements

H301 Toxic if swallowed.

Precautionary Statements

P264 Wash skin thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301 + P310 IF SWALLOWED: Immediately call a POISON CENTER/ doctor.
P405 Store locked up.
P501 Dispose of contents/ container to an approved waste disposal plant.

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03

Composition / Information on Ingredients

Chemical components, concentration ranges, and hazardous substance identification

Type substance

Substance name : N-[4-(2-Pyrimidinyl)-1-piperazinyl]butyl]-8-azaspiro[4.5]decane-7,9-dionehydrochloride

Chemical Name CAS Number Concentration Hazardous
8-[4-[4-(2-Pyrimidinyl)-1-piperazinyl]butyl]-8-azaspiro[4.5]decane-7,9-dione monohydrochloride EC: 251-489-4 33386-08-2 90 - 100% No

Sigma- B7148 The life science business of Merck operates as MilliporeSigma in the US and Canada Page 2 of 13 <!-- PAGE 3 --> Page 3 of 13

04

First Aid Measures

Emergency procedures for chemical exposure incidents

Inhalation

After inhalation: fresh air.

Skin contact

Take off immediately all contaminated clothing. Rinse skin with water/ shower.

Eye contact

After eye contact: rinse out with plenty of water. Remove contact lenses.

Ingestion

If swallowed: give water to drink (two glasses at most). Seek medical advice immediately. In exceptional cases only, if medical care is not available within one hour, induce vomiting (only in persons who are wide awake and fully conscious), administer activated charcoal (20 - 40 g in a 10% slurry) and consult a doctor as quickly as possible.

Immediate Medical Attention

Seek medical advice immediately.

05

Firefighting Measures

Extinguishing media, specific hazards, and firefighter protection

Suitable media

Water, Foam, Carbon dioxide (CO2), Dry powder

Unsuitable media

For this substance/mixture no limitations of extinguishing agents are given.

Specific hazards

Combustible.

Instructions

Suppress (knock down) gases/vapours/mists with a water spray jet.

Firefighter Protection

Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.

06

Accidental Release Measures

Spill cleanup procedures, containment, and environmental protection

Emergency procedures

Avoid inhalation of dusts. Avoid substance contact. Ensure adequate ventilation. Evacuate the danger area, observe emergency procedures, consult an expert.

Environmental

Do not let product enter drains.

Cleanup methods

Cover drains. Collect, bind, and pump off spills. Take up carefully. Dispose of properly. Clean up affected area.

Related Products

Similar products with comparable safety profiles

07

Handling and Storage

Safe handling precautions, storage conditions, and workplace requirements

Handling

Change contaminated clothing. Preventive skin protection recommended. Wash hands after working with substance.

Storage

Tightly closed. Dry. Keep in a well-ventilated place. Keep locked up or in an area accessible only to qualified or authorised persons.

Hygiene

Change contaminated clothing. Preventive skin protection recommended. Wash hands after working with substance.

08

Exposure Controls / PPE

Occupational exposure limits, engineering controls, and protective equipment

Hands

Material: Nitrile rubber, Break through time: 480 min, Glove thickness: 0,11 mm, Protective index: Full contact, Manufacturer: KCL 741 Dermatril® L; Material: Nitrile rubber, Break through time: 480 min, Glove thickness: 0,11 mm, Protective index: Splash contact, Manufacturer: KCL 741 Dermatril® L. Remarks: This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN 16523-1 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell, Internet: www.kcl.de).

Eyes

Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Safety glasses

Respiratory

required when dusts are generated. Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system. Recommended Filter : Filter type P3. The entrepreneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer. These measures have to be properly documented.

Skin/Body

protective clothing

Environmental

Do not let product enter drains.

09

Physical and Chemical Properties

Appearance, physical state, melting point, boiling point, and material characteristics

Vapor Density
---
Solubility In Water
---
Flammability
---
Colour Intensity
---
Molecular Weight
421,96 g/mol
Relative Density
---
Odor Threshold
---
Voc Content
---
Metal Corrosion
---
Physical State
solid
Decomposition Temperature
---
Explosive Limits
---
Solubility
---
Form
---
Cloud Point
---
Auto Ignition Temperature
---
Properties Status
---
Upper Explosive Limit
---
Softening Point
---
Dynamic Viscosity
---
Density
---
Kinematic Viscosity
---
Lower Explosive Limit
---
Odor
---
Melting Point
201,5 - 202,5 °C
Crystallisation Point
---
Physical State Data
solid
Evaporation Rate
No data available
Solubility In Fat
---
Solidification Point
---
Ph
---
Colour
---
Flash Point
---
Boiling Point
---
Appearance
---
State Under Standard Conditions
---
Partition Coefficient
---
Vapor Pressure
---
Freezing Point
---
Relative Evaporation Rate
---
Bulk Density
---
10

Stability and Reactivity

Chemical stability, hazardous reactions, and incompatible materials

Stability

The product is chemically stable under standard ambient conditions (room temperature).

Reactivity

The following applies in general to flammable organic substances and mixtures: in correspondingly fine distribution, when whirled up a dust explosion potential may generally be assumed.

Hazardous reactions

No data available

Avoid

no information available

Incompatible

Strong oxidizing agents

Decomposition

In the event of fire: see section 5

12

Ecological Information

Environmental toxicity, biodegradation, and bioaccumulation data

The data for this section has not been processed yet.

13

Disposal Considerations

Waste treatment methods, disposal recommendations, and waste codes

The data for this section has not been processed yet.

14

Transport Information

UN numbers, shipping names, transport classes, and regulatory requirements

UN Number
2811
Shipping Name
TOXIC SOLID, ORGANIC, N.O.S. (Buspirone hydrochloride)
Transport Class
6.1
Packing Group
III
15

Regulatory Information

Chemical regulations, safety assessments, and compliance status

The data for this section has not been processed yet.

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Frequently Asked Questions

Common questions about safety, handling, and properties

What is the hazard signal word for Buspirone hydrochloride?

The signal word is danger.

What is the physical form of Buspirone hydrochloride?

Buspirone hydrochloride is a solid .

What is Buspirone hydrochloride used for?

Laboratory chemicals, Manufacture of substances

What are the hazard statements for Buspirone hydrochloride?

This substance has 1 hazard statement:

  • H301: Toxic if swallowed.

What is the melting point of Buspirone hydrochloride?

The melting point is 201,5 - 202,5 °C .