Identification
Product identifiers, regulatory numbers, and supplier information
Product Information
- Product Name
- Bupropion Hydrochloride
- Product Code
- 1078733
- Chemical Name
- 1-Propanone, 1-(3-chlorophenyl)-2-[(1,1-dimethylethyl)amino]-, hydrochloride, (+/-)-
- Synonyms
- Amfebutamone
Regulatory Identifiers
- CAS Number
- 31677-93-7 Check regulations →
Identified Uses
Specified quality tests and assay use only.
Uses advised against
Not for use as a drug. Not for administration to humans or animals.
Manufacturers & Suppliers
U. S. Pharmacopeia
manufacturer
12601 Twinbrook Parkway, Rockville, MD 20852-1790, United States
301-816-8129
http://www.usp.org
Emergency Contacts
CHEMTREC within US & Canada
1-800-424-9300
CHEMTREC outside US & Canada
+1 703-527-3887
Hazard Identification
GHS classification, signal word, pictograms, and hazard statements
Hazard Classifications
GHS Pictograms
GHS07
Hazard Statements
Precautionary Statements
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Composition / Information on Ingredients
Chemical components, concentration ranges, and hazardous substance identification
| Chemical Name | CAS Number | Concentration | Hazardous |
|---|---|---|---|
| Bupropion Hydrochloride | 31677-93-7 | 100% | No |
First Aid Measures
Emergency procedures for chemical exposure incidents
Move to fresh air. Call a physician if symptoms develop or persist.
Get medical attention if irritation develops and persists.
Immediately flush eyes with plenty of water for at least 15 minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Get medical attention if irritation develops and persists.
Rinse mouth. If vomiting occurs, keep head low so that stomach content doesn't get into the lungs. Get medical advice/attention if you feel unwell.
Immediate Medical Attention
Persons developing serious hypersensitivity (anaphylactic) reactions must receive immediate medical attention.
Medical Treatment
Treatment of overdose should be symptomatic and supportive. Administer activated charcoal as a slurry. Perform gastric lavage. Perform aggressive airway management. Monitor vital signs. Monitor ECG. Monitor fluid and electrolyte status. For seizures, administer a benzodiazepine intravenously, followed by phenobarbital or propofol if the seizures recur. Monitor for hypotension, dysrhythmias, respiratory depression, and need for endotracheal intubation. Evaluate for hypoglycemia, electrolyte disturbances, hypoxia. For hypotension, infuse 10- 20 mL/kg isotonic fluid. Administer dopamine or norepinephrine if hypotension persists. For agitation, administer benzodiazepines. Hemodialysis is unlikely to be of benefit.
Firefighting Measures
Extinguishing media, specific hazards, and firefighter protection
Water. Foam. Dry chemical or CO2. Use fire-extinguishing media appropriate for surrounding materials.
None known.
No unusual fire or explosion hazards noted.
Use water spray to cool unopened containers. Use standard firefighting procedures and consider the hazards of other involved materials.
Firefighter Protection
Wear suitable protective equipment. Firefighters should use self-contained breathing equipment and protective clothing.
Accidental Release Measures
Spill cleanup procedures, containment, and environmental protection
Keep unnecessary personnel away. Wear appropriate personal protective equipment. Avoid inhalation of dust from the spilled material. Do not touch damaged containers or spilled material unless wearing appropriate protective clothing. Ensure adequate ventilation.
Avoid discharge into drains, water courses or onto the ground.
Sweep up or vacuum up spillage and collect in suitable container for disposal. Clean surface thoroughly to remove residual contamination.
Materials: suitable container
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Handling and Storage
Safe handling precautions, storage conditions, and workplace requirements
As a general rule, when handling USP Reference Standards, avoid all contact and inhalation of dust, mists, and/or vapors associated with the material. Clean equipment and work surfaces with suitable detergent or solvent after use. After removing gloves, wash hands and other exposed skin thoroughly. Select and use containment devices and personal protective equipment based on a risk assessment of material potency and exposure potential.
Store in tight container as defined in the USP-NF. This material should be handled and stored per label instructions to ensure product integrity.
After removing gloves, wash hands and other exposed skin thoroughly.
Exposure Controls / PPE
Occupational exposure limits, engineering controls, and protective equipment
Physical and Chemical Properties
Appearance, physical state, melting point, boiling point, and material characteristics
Stability and Reactivity
Chemical stability, hazardous reactions, and incompatible materials
Material is stable under normal conditions.
The product is stable and non-reactive under normal conditions of use, storage and transport.
No dangerous reaction known under conditions of normal use.
Contact with incompatible materials.
Strong oxidizing agents.
NOx. Cl-. Irritating and/or toxic fumes or gases. Emits toxic fumes under fire conditions.
Ecological Information
Environmental toxicity, biodegradation, and bioaccumulation data
The data for this section has not been processed yet.
Disposal Considerations
Waste treatment methods, disposal recommendations, and waste codes
The data for this section has not been processed yet.
Transport Information
UN numbers, shipping names, transport classes, and regulatory requirements
Regulatory Information
Chemical regulations, safety assessments, and compliance status
The data for this section has not been processed yet.
Frequently Asked Questions
Common questions about safety, handling, and properties
What other names is Bupropion Hydrochloride known by?
Bupropion Hydrochloride is also known as: Amfebutamone
What is the hazard signal word for Bupropion Hydrochloride?
The signal word is warning.
What is the physical form of Bupropion Hydrochloride?
Bupropion Hydrochloride is a solid. appearing as white. off-white. with white. off-white. color. It has odorless. characteristic. odor.
What is Bupropion Hydrochloride used for?
Specified quality tests and assay use only.
What are the hazard statements for Bupropion Hydrochloride?
This substance has 2 hazard statements:
- H302: Harmful if swallowed.
- H319: Causes serious eye irritation.
What is the melting point of Bupropion Hydrochloride?
The melting point is 428 - 453.2 °F (220 - 234 °C) (decomposes) and the boiling point is Not available..