Niacin

Move to fresh air. Call a physician if symptoms develop or persist.

Rinse skin with water/shower. Get medical attention if irritation develops and persists.

Rinse cautiously with water for several minutes. Get medical attention if irritation develops and persists.

Symptoms: Irritation of eyes

Rinse mouth. If ingestion of a large amount does occur, call a poison control center immediately.

Use fire-extinguishing media appropriate for surrounding materials. Water. Foam. Dry chemical or CO2.

None known.

No unusual fire or explosion hazards noted.

Use water spray to cool unopened containers. As with all fires, evacuate personnel to a safe area. Use standard firefighting procedures and consider the hazards of other involved materials.

Keep unnecessary personnel away. Do not touch damaged containers or spilled material unless wearing appropriate protective clothing.

Sweep up or vacuum up spillage and collect in suitable container for disposal.

Materials: suitable container

As a general rule, when handling USP Reference Standards, avoid all contact and inhalation of dust, mists, and/or vapors associated with the material. Clean equipment and work surfaces with suitable detergent or solvent after use. After removing gloves, wash hands and other exposed skin thoroughly.

Store in tight container as defined in the USP-NF. This material should be handled and stored per label instructions to ensure product integrity.

Clean equipment and work surfaces with suitable detergent or solvent after use. After removing gloves, wash hands and other exposed skin thoroughly.

Airborne exposure should be controlled primarily by engineering controls such as general dilution ventilation, local exhaust ventilation, or process enclosure. Local exhaust ventilation is generally preferred to general exhaust because it can control the contaminant at its source, preventing dispersion into the work area. An industrial hygiene survey involving air monitoring may be used to determine the effectiveness of engineering controls. Effectiveness of engineering controls intended for use with highly potent materials should be assessed by use of nontoxic surrogate materials.

Chemically compatible gloves. For handling solutions, ensure that the glove material is protective against the solvent being used. Use handling practices that minimize direct hand contact. Employees who are sensitive to natural rubber (latex) should use nitrile or other synthetic nonlatex gloves. Use of powdered latex gloves should be avoided due to the risk of latex allergy.

Safety glasses with sideshields are recommended. Face shields or goggles may be required if splash potential exists or if corrosive materials are present. Approved eye protection (e.g., bearing the ANSI Z87 or CSA stamp) is preferred. Maintain eyewash facilities in the work area.

Where respirators are deemed necessary to reduce or control occupational exposures, use NIOSH-approved respiratory protection and have an effective respirator program in place (applicable U.S. regulation OSHA 29 CFR 1910.134).

For handling of laboratory scale quantities, a cloth lab coat is recommended. Where significant quantities are handled, work clothing may be necessary to prevent take-home contamination.

Stable at normal conditions.

No reactivity hazards known.

No dangerous reaction known under conditions of normal use.

None known.

Strong oxidizers. Strong acids. Strong bases. Sodium nitrite.

NOx. Irritating and/or toxic fumes or gases. Emits toxic fumes under fire conditions.