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Safety Data Sheet EN

Histamine dihydrochloride

CAS 56-92-8

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01

Identification

Product identifiers, regulatory numbers, and supplier information

Product Information

Product Name
Histamine dihydrochloride
Product Code
H7250

Regulatory Identifiers

CAS Number
56-92-8 Check regulations →
REACH No.
A registration number is not available for this substance as the substance or its uses are exempted from registration, the annual tonnage does not require a registration or the registration is envisaged for a later registration deadline.

Identified Uses

Laboratory chemicals, Manufacture of substances

Manufacturers & Suppliers

S

Sigma

manufacturer

M

Merck Life Science BV/SRL

manufacturer

Brusselsesteenweg 288, B-3090 OVERIJSE

+32 (0)3 899-1301

Emergency Contacts

CHEMTREC

+(32) 28 083237

Anti-poison centre

070 245245

02

Hazard Identification

GHS classification, signal word, pictograms, and hazard statements

Classified danger

Hazard Classifications

Skin Irrit. Cat. 2 H315
Eye Irrit. Cat. 2 H319
Resp. Sens. Cat. 1 H334
Skin Sens. Cat. 1 H317
STOT SE Cat. 3 H335

GHS Pictograms

GHS07 - Health hazard

GHS07

GHS08 - Serious health hazard

GHS08

Hazard Statements

H315 Causes skin irritation.
H317 May cause an allergic skin reaction.
H319 Causes serious eye irritation.
H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled.
H335 May cause respiratory irritation.

Precautionary Statements

P261 Avoid breathing dust.
P264 Wash skin thoroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/ eye protection/ face protection.
P302 + P352 IF ON SKIN: Wash with plenty of water.
P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

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03

Composition / Information on Ingredients

Chemical components, concentration ranges, and hazardous substance identification

Type substance
Chemical Name CAS Number Concentration Hazardous
histamine dihydrochloride EC: 200-298-4 56-92-8 100% Yes
04

First Aid Measures

Emergency procedures for chemical exposure incidents

Inhalation

Fresh air. Call in physician.

Skin contact

Take off immediately all contaminated clothing. Rinse skin with water/ shower. Consult a physician.

Eye contact

Rinse out with plenty of water. Call in ophthalmologist. Remove contact lenses.

Ingestion

Immediately make victim drink water (two glasses at most). Consult a physician.

Immediate Medical Attention

Call in physician. Call in ophthalmologist.

05

Firefighting Measures

Extinguishing media, specific hazards, and firefighter protection

Suitable media

Water Foam Carbon dioxide (CO2) Dry powder

Unsuitable media

For this substance/mixture no limitations of extinguishing agents are given.

Specific hazards

Combustible. Development of hazardous combustion gases or vapours possible in the event of fire.

Instructions

Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.

Firefighter Protection

Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.

06

Accidental Release Measures

Spill cleanup procedures, containment, and environmental protection

Emergency procedures

Avoid inhalation of dusts. Avoid substance contact. Ensure adequate ventilation. Evacuate the danger area, observe emergency procedures, consult an expert.

Environmental

Do not let product enter drains.

Cleanup methods

Take up carefully. Clean up affected area.

Related Products

Similar products with comparable safety profiles

07

Handling and Storage

Safe handling precautions, storage conditions, and workplace requirements

Handling

Work under hood. Do not inhale substance/mixture.

Storage

Tightly closed. Dry. Keep locked up or in an area accessible only to qualified or authorized persons. Keep in a dry place. Store with desiccant.

Hygiene

Immediately change contaminated clothing. Apply preventive skin protection. Wash hands and face after working with substance.

08

Exposure Controls / PPE

Occupational exposure limits, engineering controls, and protective equipment

Hands

Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of Regulation (EU) 2016/425 and the standard EN 374 derived from it. Full contact Material: Nitrile rubber Minimum layer thickness: 0,11 mm Break through time: 480 min Material tested: Dermatril® (KCL 740 / Aldrich Z677272, Size M) Splash contact Material: Nitrile rubber Minimum layer thickness: 0,11 mm Break through time: 480 min Material tested: Dermatril® (KCL 740 / Aldrich Z677272, Size M) data source: KCL GmbH, D-36124 Eichenzell, phone +49 (0)6659 87300, e-mail sales@kcl.de, test method: EN374 If used in solution, or mixed with other substances, and under conditions which differ from EN 374, contact the supplier of the EC approved gloves. This recommendation is advisory only and must be evaluated by an industrial hygienist and safety officer familiar with the specific situation of anticipated use by our customers. It should not be construed as offering an approval for any specific use scenario.

Eyes

Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Safety glasses

Respiratory

required when dusts are generated. Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system. Recommended Filter type: Filter type P2 The entrepreneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer. These measures have to be properly documented.

Skin/Body

protective clothing

Environmental

Do not let product enter drains.

09

Physical and Chemical Properties

Appearance, physical state, melting point, boiling point, and material characteristics

Physical State Data
solid
Decomposition Temperature
No data available
Relative Evaporation Rate
---
Molecular Weight
---
Freezing Point
---
Colour Intensity
---
Crystallisation Point
---
Appearance
---
Properties Status
---
Ph
No data available
Lower Explosive Limit
---
Odor
No data available
Bulk Density
---
Flash Point
No data available
Form
---
Colour
white
Density
No data available
State Under Standard Conditions
---
Melting Point
Melting point/range: 249 - 252 °C
Vapor Pressure
No data available
Evaporation Rate
---
Physical State
powder
Boiling Point
No data available
Solubility In Water
No data available
Explosive Limits
---
Solubility In Fat
---
Softening Point
---
Auto Ignition Temperature
No data available
Metal Corrosion
---
Upper Explosive Limit
---
Voc Content
---
Vapor Density
---
Partition Coefficient
No data available
Odor Threshold
---
Cloud Point
---
Solubility
---
Solidification Point
---
Flammability
---
Kinematic Viscosity
No data available
Dynamic Viscosity
No data available
Relative Density
No data available
10

Stability and Reactivity

Chemical stability, hazardous reactions, and incompatible materials

Stability

The product is chemically stable under standard ambient conditions (room temperature).

Reactivity

The following applies in general to flammable organic substances and mixtures: in correspondingly fine distribution, when whirled up a dust explosion potential may generally be assumed.

Hazardous reactions

No data available

Avoid

no information available

Incompatible

Strong oxidizing agents

Decomposition

In the event of fire: see section 5

12

Ecological Information

Environmental toxicity, biodegradation, and bioaccumulation data

The data for this section has not been processed yet.

13

Disposal Considerations

Waste treatment methods, disposal recommendations, and waste codes

The data for this section has not been processed yet.

14

Transport Information

UN numbers, shipping names, transport classes, and regulatory requirements

15

Regulatory Information

Chemical regulations, safety assessments, and compliance status

The data for this section has not been processed yet.

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Frequently Asked Questions

Common questions about safety, handling, and properties

What is the hazard signal word for Histamine dihydrochloride?

The signal word is danger.

What is the physical form of Histamine dihydrochloride?

Histamine dihydrochloride is a powder with white color. It has no data available odor.

What is Histamine dihydrochloride used for?

Laboratory chemicals, Manufacture of substances

What are the hazard statements for Histamine dihydrochloride?

This substance has 5 hazard statements:

  • H315: Causes skin irritation.
  • H317: May cause an allergic skin reaction.
  • H319: Causes serious eye irritation.
  • H334: May cause allergy or asthma symptoms or breathing difficulties if inhaled.
  • H335: May cause respiratory irritation.

What is the melting point of Histamine dihydrochloride?

The melting point is Melting point/range: 249 - 252 °C and the boiling point is No data available.