Levothyroxine

Move to fresh air. Call a physician if symptoms develop or persist.

Rinse skin with water/shower. Get medical attention if irritation develops and persists.

Rinse with water. Get medical attention if irritation develops and persists.

Rinse mouth. If ingestion of a large amount does occur, call a poison control center immediately.

Water. Foam. Dry chemical or CO2. Use fire-extinguishing media appropriate for surrounding materials.

None known.

Explosion hazard: Avoid generating dust; fine dust dispersed in air in sufficient concentrations and in the presence of an ignition source is a potential dust explosion hazard.

Use water spray to cool unopened containers. As with all fires, evacuate personnel to a safe area. Use standard firefighting procedures and consider the hazards of other involved materials.

Keep unnecessary personnel away. Wear appropriate personal protective equipment. Avoid inhalation of dust from the spilled material. Do not touch damaged containers or spilled material unless wearing appropriate protective clothing.

Avoid discharge into drains, water courses or onto the ground.

Sweep up or vacuum up spillage and collect in suitable container for disposal.

As a general rule, when handling USP Reference Standards, avoid all contact and inhalation of dust, mists, and/or vapors associated with the material. Clean equipment and work surfaces with suitable detergent or solvent after use. After removing gloves, wash hands and other exposed skin thoroughly. Avoid significant deposits of material, especially on horizontal surfaces, which may become airborne and form combustible dust clouds and may contribute to secondary explosions. Combustible dust clouds may be created where operations produce fine material (dust). Select and use containment devices and personal protective equipment based on a risk assessment of material potency and exposure potential.

Store in tight container as defined in the USP-NF. This material should be handled and stored per label instructions to ensure product integrity.

Clean equipment and work surfaces with suitable detergent or solvent after use. After removing gloves, wash hands and other exposed skin thoroughly.

Avoid significant deposits of material, especially on horizontal surfaces, which may become airborne and form combustible dust clouds and may contribute to secondary explosions.

No open handling. For laboratory operations, conduct powder handling operations in an isolator or equivalent. Put powder into solution or a tightly capped container prior to removal from containment. Isolator should be equipped with bag out ports or transfer chamber. Control exposures to below the occupational exposure level (if available). Select and use containment devices and personal protective equipment based on a risk assessment of exposure potential. Cover all containers for solutions and slurries while being transferred.

Wear double gloves. Wear nitrile or other impervious gloves if skin contact is possible. When the material is dissolved or suspended in an organic solvent, wear gloves that provide protection against the solvent.

Wear safety glasses with side shields, chemical splash goggles, or full face shield, if necessary. Base the choice of protection on the job activity and potential for contact with eyes or face. An emergency eye wash station should be available.

Use a powered air-purifying respirator (PAPR) with HEPA filters, disposable outerware and head cover for spill cleanup. Chose respiratory protection appropriate to the task and the level of existing engineering controls.

Wear disposable laboratory coat and disposable sleeve covers appropriate to the task, two pairs of gloves, and safety glasses with side shields. Base the choice of skin protection on the job activity, potential for skin contact and solvents and reagents in use.

Material is stable under normal conditions.

The product is stable and non-reactive under normal conditions of use, storage and transport.

No dangerous reaction known under conditions of normal use.

Contact with incompatible materials.

Strong oxidizing agents. Strong bases.

Irritating and/or toxic fumes or gases. Emits toxic fumes under fire conditions. I-. NOx.