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Safety Data Sheet EN

L-Thyroxine

CAS 51-48-9

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01

Identification

Product identifiers, regulatory numbers, and supplier information

Product Information

Product Name
L-Thyroxine
Product Code
T2376
Chemical Name
L-Thyroxine

Regulatory Identifiers

CAS Number
51-48-9 Check regulations →
REACH No.
A registration number is not available for this substance as the substance or its uses are exempted from registration or the annual tonnage does not require a registration.

Identified Uses

Laboratory chemicals, Manufacture of substances

Manufacturers & Suppliers

M

Merck Life Science BV

manufacturer

Ildefonse Vandammestraat 5/7B, B-1560 HOEILAART

+32 (0)3 899-1301

Emergency Contacts

CHEMTREC

+(32) 28 083237

Anti-poison centre

070 245245

02

Hazard Identification

GHS classification, signal word, pictograms, and hazard statements

Classified danger

Hazard Classifications

STOT RE Cat. 1 H372

GHS Pictograms

GHS08 - Serious health hazard

GHS08

Hazard Statements

H372 Causes damage to organs (Thyroid, Cardio-vascular system, Kidney) through prolonged or repeated exposure.

Precautionary Statements

P260 Do not breathe dust.
P264 Wash skin thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P314 Get medical advice/ attention if you feel unwell.
P501 Dispose of contents/ container to an approved waste disposal plant.

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03

Composition / Information on Ingredients

Chemical components, concentration ranges, and hazardous substance identification

Type substance
Chemical Name CAS Number Concentration Hazardous
L-thyroxine EC: 200-101-1 51-48-9 100% Yes
04

First Aid Measures

Emergency procedures for chemical exposure incidents

Inhalation

After inhalation: fresh air. Call in physician.

Skin contact

In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with water/ shower. Consult a physician.

Eye contact

After eye contact: rinse out with plenty of water. Call in ophthalmologist. Remove contact lenses.

Ingestion

After swallowing: immediately make victim drink water (two glasses at most). Consult a physician.

05

Firefighting Measures

Extinguishing media, specific hazards, and firefighter protection

Suitable media

Water, Foam, Carbon dioxide (CO2), Dry powder

Unsuitable media

For this substance/mixture no limitations of extinguishing agents are given.

Specific hazards

Carbon oxides, Nitrogen oxides (NOx), Hydrogen iodide. Combustible. Development of hazardous combustion gases or vapours possible in the event of fire.

Instructions

Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.

Firefighter Protection

Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.

06

Accidental Release Measures

Spill cleanup procedures, containment, and environmental protection

Emergency procedures

Avoid generation and inhalation of dusts in all circumstances. Avoid substance contact. Ensure adequate ventilation. Evacuate the danger area, observe emergency procedures, consult an expert.

Environmental

Do not let product enter drains.

Cleanup methods

Take up dry. Clean up affected area.

Related Products

Similar products with comparable safety profiles

07

Handling and Storage

Safe handling precautions, storage conditions, and workplace requirements

Handling

For precautions see section 2.2.

Storage

Tightly closed. Dry. Keep in a well-ventilated place. Keep locked up or in an area accessible only to qualified or authorised persons.

08

Exposure Controls / PPE

Occupational exposure limits, engineering controls, and protective equipment

Hands

Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of Regulation (EU) 2016/425 and the standard EN 374 derived from it. Full contact: Material: Nitrile rubber, Minimum layer thickness: 0,11 mm, Break through time: 480 min, Material tested: Dermatril® (KCL 740 / Aldrich Z677272, Size M). Splash contact: Material: Nitrile rubber, Minimum layer thickness: 0,11 mm, Break through time: 480 min, Material tested: Dermatril® (KCL 740 / Aldrich Z677272, Size M). data source: KCL GmbH, D-36124 Eichenzell, phone +49 (0)6659 87300, e-mail sales@kcl.de, test method: EN374. If used in solution, or mixed with other substances, and under conditions which differ from EN 374, contact the supplier of the CE approved gloves. This recommendation is advisory only and must be evaluated by an industrial hygienist and safety officer familiar with the specific situation of anticipated use by our customers. It should not be construed as offering an approval for any specific use scenario.

Eyes

Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Safety glasses

Respiratory

required when dusts are generated. Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system. Recommended Filter type: Filter type P2. The entrepreneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer. These measures have to be properly documented.

Skin/Body

protective clothing

Environmental

Do not let product enter drains.

09

Physical and Chemical Properties

Appearance, physical state, melting point, boiling point, and material characteristics

Partition Coefficient
log Pow: 2,727 - 2,73 at 25 °C - OECD Test Guideline 117 - n-octanol/water Bioaccumulation is not expected.
Solidification Point
---
Odor
No data available
Explosive Limits
---
Appearance
---
Kinematic Viscosity
No data available
Vapor Density
---
Bulk Density
---
Evaporation Rate
---
Melting Point
Melting point/ range: 223 °C - dec.
Dynamic Viscosity
No data available
Cloud Point
---
Solubility
---
State Under Standard Conditions
---
Odor Threshold
---
Solubility In Fat
---
Density
ca.2,43 g/cm3 at 20 °C - OECD Test Guideline 109
Relative Density
2,44 at 20 °C - OECD Test Guideline 109
Physical State Data
solid
Physical State
solid
Form
---
Auto Ignition Temperature
---
Flash Point
Not applicable
Boiling Point
No data available
Freezing Point
---
Vapor Pressure
< 0,1 hPa at 25 °C - OECD Test Guideline 104
Metal Corrosion
---
Colour
No data available
Softening Point
---
Ph
No data available
Molecular Weight
---
Properties Status
---
Lower Explosive Limit
---
Relative Evaporation Rate
---
Voc Content
---
Colour Intensity
---
Solubility In Water
No data available
Decomposition Temperature
---
Crystallisation Point
---
Upper Explosive Limit
---
Flammability
---
10

Stability and Reactivity

Chemical stability, hazardous reactions, and incompatible materials

Stability

The product is chemically stable under standard ambient conditions (room temperature).

Reactivity

The following applies in general to flammable organic substances and mixtures: in correspondingly fine distribution, when whirled up a dust explosion potential may generally be assumed.

Hazardous reactions

Violent reactions possible with: strong oxidising agents, Strong bases

Avoid

no information available

Incompatible

No data available

Decomposition

In the event of fire: see section 5

12

Ecological Information

Environmental toxicity, biodegradation, and bioaccumulation data

The data for this section has not been processed yet.

13

Disposal Considerations

Waste treatment methods, disposal recommendations, and waste codes

The data for this section has not been processed yet.

14

Transport Information

UN numbers, shipping names, transport classes, and regulatory requirements

15

Regulatory Information

Chemical regulations, safety assessments, and compliance status

The data for this section has not been processed yet.

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Frequently Asked Questions

Common questions about safety, handling, and properties

What is the hazard signal word for L-Thyroxine?

The signal word is danger.

What is the physical form of L-Thyroxine?

L-Thyroxine is a solid with no data available color. It has no data available odor.

What is L-Thyroxine used for?

Laboratory chemicals, Manufacture of substances

What are the hazard statements for L-Thyroxine?

This substance has 1 hazard statement:

  • H372: Causes damage to organs (Thyroid, Cardio-vascular system, Kidney) through prolonged or repeated exposure.

What is the melting point of L-Thyroxine?

The melting point is Melting point/ range: 223 °C - dec. and the boiling point is No data available.