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Safety Data Sheet EN

SAG

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01

Identification

Product identifiers, regulatory numbers, and supplier information

Product Information

Product Name
SAG
Product Code
DX21210
Chemical Name
3-chloro-N-[4-(methylamino)cyclohexyl]-N-[(3-pyridin-4-ylphenyl)methyl]-1-benzothiophene-2-carboxamide
Synonyms
Smoothened Agonist; 3-chloro-N-[trans-4-(methylamino)cyclohexyl]-N-[[3-(4-pyridinyl)phenyl]methyl]-benzo[b]thio phene-2-carboxamide;

Regulatory Identifiers

CAS Number
N/A

Identified Uses

Laboratory chemicals

Uses advised against

No information available

Manufacturers & Suppliers

S

STEMCELL Technologies SARL

manufacturer

40 Rue des Berges, Miniparc Polytec, Bâtiment Sirocco, 38000 Grenoble, France

+33 (0) 4 76 04 75 30

S

STEMCELL Technologies Germany GmbH

manufacturer

Stolberger Str. 200, 50933, Köln, Germany

+33 (0) 4 76 04 75 30

S

STEMCELL Technologies UK Ltd.

manufacturer

Building 7100, Cambridge Research Park, Beach Drive, Waterbeach, Cambridge, UK, CB25 9TL

+33 (0) 4 76 04 75 30

Emergency Contacts

Emergency Contact

112

02

Hazard Identification

GHS classification, signal word, pictograms, and hazard statements

Classified danger

Hazard Classifications

Acute Tox. Cat. 3 H301
Aquatic Chronic Cat. 4 H413

GHS Pictograms

GHS06 - Acute toxicity

GHS06

Hazard Statements

H301 Toxic if swallowed
H413 May cause long lasting harmful effects to aquatic life

Precautionary Statements

P301 + P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor

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03

Composition / Information on Ingredients

Chemical components, concentration ranges, and hazardous substance identification

Type substance
Chemical Name CAS Number Concentration Hazardous
3-chloro-N-[4-(methylamino)cyclohexyl]-N-[(3-pyridin-4-ylphenyl)methyl]-1-benzothiophene-2-carboxamide 912545-86-9 100% Yes
04

First Aid Measures

Emergency procedures for chemical exposure incidents

Inhalation

Remove to fresh air.

Skin contact

Wash skin with soap and water. In the case of skin irritation or allergic reactions see a physician.

Eye contact

Rinse thoroughly with plenty of water for at least 15 minutes, lifting lower and upper eyelids. Consult a physician.

Ingestion

Do NOT induce vomiting. Clean mouth with water and drink afterwards plenty of water. Never give anything by mouth to an unconscious person. Get medical attention.

Immediate Medical Attention

Consult a physician / Get medical attention.

Medical Treatment

Treat symptomatically.

05

Firefighting Measures

Extinguishing media, specific hazards, and firefighter protection

Suitable media

Use extinguishing measures that are appropriate to local circumstances and the surrounding environment.

Unsuitable media

No information available.

Specific hazards

No information available.

Firefighter Protection

Firefighters should wear self-contained breathing apparatus and full firefighting turnout gear. Use personal protection equipment.

06

Accidental Release Measures

Spill cleanup procedures, containment, and environmental protection

Environmental

See Section 12 for additional Ecological Information.

Cleanup methods

Take up mechanically, placing in appropriate containers for disposal.

—

Related Products

Similar products with comparable safety profiles

07

Handling and Storage

Safe handling precautions, storage conditions, and workplace requirements

Handling

Ensure adequate ventilation.

Storage

Store in accordance with information listed on the Product Information Sheet (PIS).

Hygiene

Handle in accordance with good industrial hygiene and safety practice.

08

Exposure Controls / PPE

Occupational exposure limits, engineering controls, and protective equipment

Eyes

No special protective equipment required.

Respiratory

No protective equipment is needed under normal use conditions. If exposure limits are exceeded or irritation is experienced, ventilation and evacuation may be required.

Skin/Body

No special protective equipment required.

09

Physical and Chemical Properties

Appearance, physical state, melting point, boiling point, and material characteristics

Language Code
---
Physical State
Solid
Physical State Data
solid
State Under Standard Conditions
---
Appearance
Crystalline
Colour
No information available
Colour Intensity
---
Form
---
Odor
No data available.
Odor Threshold
No data available
Ph
No data available
Melting Point
No data available
Boiling Point
No data available
Flash Point
No data available
Freezing Point
---
Softening Point
No information available
Solidification Point
---
Cloud Point
---
Crystallisation Point
---
Relative Evaporation Rate
---
Evaporation Rate
No data available
Vapor Pressure
No data available
Vapor Density
No data available
Relative Density
No data available
Bulk Density
No information available
Density
---
Flammability
Product is not flammable.
Upper Explosive Limit
No data available
Lower Explosive Limit
No data available
Explosive Limits
---
Auto Ignition Temperature
No data available
Decomposition Temperature
No data available
Solubility
DMF: 20 mg/mL; DMSO: 20 mg/mL; Ethanol: 20 mg/mL; Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/mL
Partition Coefficient
No data available
Solubility In Water
No data available
Solubility In Fat
---
Molecular Weight
490.1
Voc Content
---
Metal Corrosion
---
Dynamic Viscosity
No data available
Kinematic Viscosity
No data available
Properties Status
---
10

Stability and Reactivity

Chemical stability, hazardous reactions, and incompatible materials

Stability

Stable under recommended transport or storage conditions.

Reactivity

No information available.

Hazardous reactions

None under normal processing.

Avoid

None known based on information supplied.

Incompatible

Strong oxidizing agents.

Decomposition

Carbon dioxide (CO2). Carbon monoxide. Hydrogen sulfide. Nitrogen oxides (NOx). Phosgene.

12

Ecological Information

Environmental toxicity, biodegradation, and bioaccumulation data

12.1. Toxicity

Ecotoxicity May cause long lasting harmful effects to aquatic life. Unknown aquatic toxicity Contains 0 % of components with unknown hazards to the aquatic environment.

May cause long lasting harmful effects to aquatic life.

12.2. Persistence and degradability

12.3. Bioaccumulative potential

12.4. Mobility in soil

12.5. Results of PBT and vPvB assessment

12.6. Endocrine disrupting properties

12.7. Other adverse effects

12.2. Persistence and degradability

Persistence and degradability No information available.

No information available.

12.3. Bioaccumulative potential

Bioaccumulation No information available.

No information available regarding bioaccumulation.

12.4. Mobility in soil

Mobility in soil No information available.

No information available.

12.5. Results of PBT and vPvB assessment

PBT and vPvB assessment No information available.

No information available.

12.6. Other adverse effects

Other adverse effects No information available.

No information available.

13

Disposal Considerations

Waste treatment methods, disposal recommendations, and waste codes

Treatment

Dispose of in accordance with local regulations. Dispose of waste in accordance with environmental legislation.

Disposal

Dispose of in accordance with local regulations.

14

Transport Information

UN numbers, shipping names, transport classes, and regulatory requirements

UN Number
UN2811
Shipping Name
TOXIC SOLID, ORGANIC, N.O.S. (SAG)
Transport Class
6.1
Packing Group
III
15

Regulatory Information

Chemical regulations, safety assessments, and compliance status

This safety data sheet was created pursuant to the requirements of: Regulation (EC) No. 1907/2006 and Regulation (EC) No. 1272/2008. Take note of Directive 98/24/EC on the protection of the health and safety of workers from the risks related to chemical agents at work.

Chemical Safety Assessment Not performed
?

Frequently Asked Questions

Common questions about safety, handling, and properties

What other names is SAG known by?

SAG is also known as: Smoothened Agonist; 3-chloro-N-[trans-4-(methylamino)cyclohexyl]-N-[[3-(4-pyridinyl)phenyl]methyl]-benzo[b]thio phene-2-carboxamide;

What is the hazard signal word for SAG?

The signal word is danger.

What is the physical form of SAG?

SAG is a solid appearing as crystalline with no information available color. It has no data available. odor.

What is the solubility of SAG?

DMF: 20 mg/mL; DMSO: 20 mg/mL; Ethanol: 20 mg/mL; Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/mL

What is SAG used for?

Laboratory chemicals

What are the hazard statements for SAG?

This substance has 2 hazard statements:

  • H301: Toxic if swallowed
  • H413: May cause long lasting harmful effects to aquatic life

What is the melting point of SAG?

The melting point is No data available and the boiling point is No data available.