NextSDS Logo
Safety Data Sheet EN

Cal 1

Keep this SDS organized and up to date

Add this SDS to your NextSDS library and keep all its safety information in one place.

Add to my SDS library for free
01

Identification

Product identifiers, regulatory numbers, and supplier information

Product Information

Product Name
Cal 1

Regulatory Identifiers

CAS Number
N/A

Identified Uses

Laboratory chemicals, Refer to product literature for further details.

Manufacturers & Suppliers

R

Roche Diagnostics Limited

manufacturer

Charles Avenue, Burgess Hill, RH15 9RY West Sussex, United Kingdom

+44 1444 256000

Emergency Contacts

Roche Diagnostics Ltd.

+44 (0)808 100 1920

Roche Diagnostics Ltd.

1800 409 564

NPIS

+44 344 892 0111

24Hr

NHS Direct in Wales

111

24Hr

NHS Direct in Wales

+44 845 4647111

24Hr

NHS 24

111

02

Hazard Identification

GHS classification, signal word, pictograms, and hazard statements

Classified warning

Hazard Classifications

Skin Sens. Cat. 1 H317
Aquatic Chronic Cat. 3 H412

GHS Pictograms

GHS07 - Health hazard

GHS07

Hazard Statements

H317 May cause an allergic skin reaction.
H412 Harmful to aquatic life with long lasting effects.

Precautionary Statements

P261 Avoid breathing dust.
P273 Avoid release to the environment.
P280 Wear protective gloves.
P333 + P313 If skin irritation or rash occurs: Get medical advice/ attention.
P362 + P364 Take off contaminated clothing and wash it before reuse.
P501 Dispose of contents/ container to an approved waste disposal plant.

Still copying SDS data manually?Free

You don't have to. NextSDS reads this SDS and adds the information to your library automatically.

Let NextSDS do it for me
03

Composition / Information on Ingredients

Chemical components, concentration ranges, and hazardous substance identification

Type mixture
Chemical Name CAS Number Concentration Hazardous
N-Methylisothiazolone hydrochloride EC: 247-499-3 26172-54-3 0.25 - 1% Yes
Hydrocortisone EC: 200-020-1 50-23-7 0.1% Yes
04

First Aid Measures

Emergency procedures for chemical exposure incidents

Inhalation

If unconscious, place in recovery position and seek medical advice. If symptoms persist, call a physician.

Skin contact

If on skin, rinse well with water.

Symptoms: May cause an allergic skin reaction.

Eye contact

Flush eyes with water as a precaution. Remove contact lenses. Protect unharmed eye. Keep eye wide open while rinsing. If eye irritation persists, consult a specialist.

Ingestion

Keep respiratory tract clear. Do not give milk or alcoholic beverages. Never give anything by mouth to an unconscious person. If symptoms persist, call a physician.

Medical Treatment

Treat symptomatically.

05

Firefighting Measures

Extinguishing media, specific hazards, and firefighter protection

Suitable media

Use extinguishing measures that are appropriate to local circumstances and the surrounding environment.

Unsuitable media

High volume water jet

Specific hazards

Do not allow run-off from fire fighting to enter drains or water courses.

06

Accidental Release Measures

Spill cleanup procedures, containment, and environmental protection

Emergency procedures

Use personal protective equipment. Avoid dust formation. Avoid breathing dust. Refer to protective measures listed in sections 7 and 8.

Environmental

Prevent product from entering drains. Prevent further leakage or spillage if safe to do so. If the product contaminates rivers and lakes or drains inform respective authorities.

Cleanup methods

Keep in suitable, closed containers for disposal.

—

Related Products

Similar products with comparable safety profiles

C

Cal 1

---

C

Cal 1

---

C

Cal 1

---

C

Cal 1

---

C

Cal 1

---

C

Cal 1

---

C

Cal 1

---

C

Cal 1

---

07

Handling and Storage

Safe handling precautions, storage conditions, and workplace requirements

Handling

Avoid formation of respirable particles. Do not breathe vapours/dust. Avoid exposure - obtain special instructions before use. Avoid contact with skin and eyes. For personal protection see section 8. Smoking, eating and drinking should be prohibited in the application area. Dispose of rinse water in accordance with local and national regulations. Persons susceptible to skin sensitisation problems or asthma, allergies, chronic or recurrent respiratory disease should not be employed in any process in which this mixture is being used.

Storage

Keep container tightly closed in a dry and well-ventilated place. See label, package insert or internal guidelines.

Hygiene

Wash hands before breaks and at the end of workday.

Fire prevention

Avoid dust formation.

08

Exposure Controls / PPE

Occupational exposure limits, engineering controls, and protective equipment

Hands

Protective gloves. Material: Protective gloves. Remarks: Please observe the instructions regarding permeability and breakthrough time which are provided by the supplier of the gloves. Also take into consideration the specific local conditions under which the product is used, such as the danger of cuts, abrasion, and the contact time. This recommendation is only valid for the product mentioned in the safety data sheet and provided by us and for the application specified by us. The suitability for a specific workplace should be discussed with the producers of the protective gloves.

Eyes

Eye wash bottle with pure water Tightly fitting safety goggles

Skin/Body

Choose body protection according to the amount and concentration of the dangerous substance at the work place.

09

Physical and Chemical Properties

Appearance, physical state, melting point, boiling point, and material characteristics

Language Code
---
Physical State
solid
Physical State Data
solid
State Under Standard Conditions
---
Appearance
solid
Colour
white, light yellow
Colour Intensity
---
Form
---
Odor
---
Odor Threshold
Not applicable
Ph
No data available
Melting Point
No data available
Boiling Point
No data available
Flash Point
does not flash
Freezing Point
---
Softening Point
---
Solidification Point
---
Cloud Point
---
Crystallisation Point
---
Relative Evaporation Rate
---
Evaporation Rate
No data available
Vapor Pressure
No data available
Vapor Density
---
Relative Density
No data available
Bulk Density
---
Density
---
Flammability
Sustains combustion
Upper Explosive Limit
No data available
Lower Explosive Limit
No data available
Explosive Limits
---
Auto Ignition Temperature
No data available
Decomposition Temperature
No data available
Solubility
---
Partition Coefficient
No data available
Solubility In Water
soluble
Solubility In Fat
---
Molecular Weight
---
Voc Content
---
Metal Corrosion
---
Dynamic Viscosity
Not applicable
Kinematic Viscosity
Not applicable
Properties Status
---
10

Stability and Reactivity

Chemical stability, hazardous reactions, and incompatible materials

Stability

Stable under normal conditions.

Reactivity

No dangerous reaction known under conditions of normal use.

Hazardous reactions

No decomposition if stored and applied as directed.

Avoid

No data available

Incompatible

No data available

Decomposition

No hazardous decomposition products are known.

12

Ecological Information

Environmental toxicity, biodegradation, and bioaccumulation data

12.1 Toxicity

N-Methylisothiazolone hydrochloride: Toxicity to fish: LC50 (Oncorhynchus mykiss (rainbow trout)): 4.77 mg/l Exposure time: 96 h Test Type: flow-through test Method: OECD Test Guideline 203 The value is given in analogy to the following substances: 2-methylisothiazol-3(2H)-one Toxicity to daphnia and other aquatic invertebrates : EC50 (Daphnia magna (Water flea)): 2.33 mg/l Exposure time: 48 h Test Type: static test Method: OECD Test Guideline 202 Toxicity to algae/aquatic plants : ErC50 (Pseudokirchneriella subcapitata (green algae)): 0.289 mg/l Exposure time: 72 h Test Type: static test Method: OECD Test Guideline 201 M-Factor (Acute aquatic toxicity) : 1 Toxicity to daphnia and other aquatic invertebrates (Chronic toxicity) : NOEC: 0.0442 mg/l Exposure time: 21 d Species: Daphnia magna (Water flea) Method: OECD Test Guideline 211 The value is given in analogy to the following substances: 2-methylisothiazol-3(2H)-one M-Factor (Chronic aquatic toxicity) : 1

12.1 Toxicity

Hydrocortisone: Toxicity to daphnia and other aquatic invertebrates : EC50 (Daphnia magna (Water flea)): > 100 mg/l Exposure time: 48 h Test Type: static test Analytical monitoring: yes Method: OECD Test Guideline 202 GLP: yes NOEC (Daphnia magna (Water flea)): 25 mg/l Exposure time: 48 h Test Type: static test Analytical monitoring: yes Method: OECD Test Guideline 202 GLP: yes Toxicity to microorganisms : (activated sludge): Exposure time: 22 d Test Type: aerobic GLP: yes Remarks: no adverse influence on substrate biodegradation

12.2 Persistence and degradability

Components:

12.2 Persistence and degradability

N-Methylisothiazolone hydrochloride: Biodegradability: : Test Type: aerobic Result: Not readily biodegradable. Biodegradation: 0 % Exposure time: 28 d Method: OECD Test Guideline 301B

12.2 Persistence and degradability

Hydrocortisone: Biodegradability: : Test Type: aerobic Inoculum: activated sludge, non-adapted Concentration: 20 mg/l Result: Readily biodegradable. Biodegradation: >= 96 % Exposure time: 22 d Method: OECD Test Guideline 301E GLP: yes

12.3 Bioaccumulative potential

Components:

12.3 Bioaccumulative potential

N-Methylisothiazolone hydrochloride: Bioaccumulation: : Remarks: No bioaccumulation is to be expected (log Pow <= 4). Partition coefficient: n-octanol/water : log Pow: ca. -0.44 (20 °C) Method: OECD Test Guideline 107

12.3 Bioaccumulative potential

Hydrocortisone: Partition coefficient: n-octanol/water : Remarks: Not applicable

Not applicable

12.4 Mobility in soil

No data available

12.5 Results of PBT and vPvB assessment

Assessment: This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.

The substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.

12.6 Endocrine disrupting properties

This substance/mixture does not contain components considered to have endocrine disrupting properties for environment according to UK REACH Article 57(f) at levels of 0.1% or higher.
13

Disposal Considerations

Waste treatment methods, disposal recommendations, and waste codes

Disposal

The product should not be allowed to enter drains, water courses or the soil. Do not contaminate ponds, waterways or ditches with chemical or used container. Send to a licensed waste management company.

14

Transport Information

UN numbers, shipping names, transport classes, and regulatory requirements

15

Regulatory Information

Chemical regulations, safety assessments, and compliance status

Relevant EU provisions transposed through retained EU law

Chemical Safety Assessment Not performed
?

Frequently Asked Questions

Common questions about safety, handling, and properties

What is the hazard signal word for Cal 1?

The signal word is warning.

What is the physical form of Cal 1?

Cal 1 is a solid appearing as solid with white, light yellow color.

What is Cal 1 used for?

Laboratory chemicals, Refer to product literature for further details.

What are the hazard statements for Cal 1?

This substance has 2 hazard statements:

  • H317: May cause an allergic skin reaction.
  • H412: Harmful to aquatic life with long lasting effects.

What is the melting point of Cal 1?

The melting point is No data available and the boiling point is No data available.