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Safety Data Sheet EN

R1

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01

Identification

Product identifiers, regulatory numbers, and supplier information

Product Information

Product Name
R1

Regulatory Identifiers

CAS Number
N/A

Identified Uses

For use as part of an IVD method, only

Manufacturers & Suppliers

R

Roche Diagnostics Limited

manufacturer

Charles Avenue, Burgess Hill, RH15 9RY West Sussex, United Kingdom

+44 1444 256000

Emergency Contacts

Roche Diagnostics Ltd.

+44 (0)808 100 1920

Roche Diagnostics Ltd.

1800 409 564

NPIS

+44 344 892 0111

24Hr

NHS Direct in Wales

111

24Hr

NHS Direct in Wales

+44 845 4647

24Hr

NHS 111 in England/NHS 24 in Scotland

111

02

Hazard Identification

GHS classification, signal word, pictograms, and hazard statements

Classified danger

Hazard Classifications

Met. Corr. Cat. 1 H290
Eye Irrit. Cat. 2 H319
Repr. Cat. 1B H360FD

GHS Pictograms

GHS05 - Corrosive

GHS05

GHS08 - Serious health hazard

GHS08

Hazard Statements

H290 May be corrosive to metals.
H319 Causes serious eye irritation.
H360FD May damage fertility. May damage the unborn child.

Precautionary Statements

P201 Obtain special instructions before use.
P280 Wear protective gloves/ protective clothing/ eye protection/ face protection/ hearing protection.
P308 + P313 IF exposed or concerned: Get medical advice/ attention.
P337 + P313 If eye irritation persists: Get medical advice/ attention.
P390 Absorb spillage to prevent material damage.
P501 Dispose of contents/ container to an approved waste disposal plant.

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03

Composition / Information on Ingredients

Chemical components, concentration ranges, and hazardous substance identification

Type mixture
Chemical Name CAS Number Concentration Hazardous
alpha-[(1,1,3,3-Tetramethylbutyl)phenyl]-omega-hydroxypoly(oxy-1,2-ethanediyl) 9036-19-5 1 - 2.5% Yes
Sodium metaborate tetrahydrate EC: 231-891-6 10555-76-7 0.1 - 1% Yes
Poly(oxy-1,2-ethanediyl), .alpha.-(phenylmethyl)-.omega.-[(1,1,3,3-tetramethylbutyl)phenoxy]- 60864-33-7 2.5 - 10% Yes
Sulpholane EC: 204-783-1 126-33-0 1 - 10% Yes
Dodecan-1-ol, ethoxylated EC: 500-002-6 9002-92-0 1 - 10% Yes
04

First Aid Measures

Emergency procedures for chemical exposure incidents

Inhalation

Move to fresh air. If unconscious, place in recovery position and seek medical advice. If symptoms persist, call a physician.

Skin contact

If on skin, rinse well with water.

Eye contact

In the case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Continue rinsing eyes during transport to hospital. Remove contact lenses. Protect unharmed eye. Keep eye wide open while rinsing. If eye irritation persists, consult a specialist.

Symptoms: Small amounts splashed into eyes can cause irreversible tissue damage and blindness.

Ingestion

Clean mouth with water and drink afterwards plenty of water. Keep respiratory tract clear. Do NOT induce vomiting. Do not give milk or alcoholic beverages. Never give anything by mouth to an unconscious person. If symptoms persist, call a physician. Take victim immediately to hospital.

Immediate Medical Attention

Take victim immediately to hospital.

Medical Treatment

The first aid procedure should be established in consultation with the doctor responsible for industrial medicine.

05

Firefighting Measures

Extinguishing media, specific hazards, and firefighter protection

Suitable media

Use extinguishing measures that are appropriate to local circumstances and the surrounding environment.

Unsuitable media

High volume water jet

Specific hazards

Do not allow run-off from fire fighting to enter drains or water courses.

Firefighter Protection

Wear self-contained breathing apparatus for firefighting if necessary.

06

Accidental Release Measures

Spill cleanup procedures, containment, and environmental protection

Emergency procedures

Use personal protective equipment. Refer to protective measures listed in sections 7 and 8.

Environmental

Prevent further leakage or spillage if safe to do so.

Cleanup methods

Soak up with inert absorbent material (e.g. sand, silica gel, acid binder, universal binder, sawdust). Keep in suitable, closed containers for disposal.

Materials: sand, silica gel, acid binder, universal binder, sawdust

—

Related Products

Similar products with comparable safety profiles

07

Handling and Storage

Safe handling precautions, storage conditions, and workplace requirements

Handling

Do not breathe vapours/dust. Avoid exposure - obtain special instructions before use. Avoid contact with skin and eyes. For personal protection see section 8.

Storage

Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage.

Hygiene

When using do not eat or drink. When using do not smoke. Wash hands before breaks and at the end of workday.

Fire prevention

Normal measures for preventive fire protection.

08

Exposure Controls / PPE

Occupational exposure limits, engineering controls, and protective equipment

Hands

In case of contact through splashing: Material: Nitrile rubber, Break through time: 480 min, Glove thickness: 0,11 mm. The selected protective gloves have to satisfy the specifications of Regulation (EU) 2016/425 and the standard EN 374 derived from it. This recommendation is only valid for the product mentioned in the safety data sheet and provided by us and for the application specified by us. Please observe the instructions regarding permeability and breakthrough time which are provided by the supplier of the gloves. Also take into consideration the specific local conditions under which the product is used, such as the danger of cuts, abrasion, and the contact time. The suitability for a specific workplace should be discussed with the producers of the protective gloves.

Eyes

Tightly fitting safety goggles. Wear face-shield and protective suit for abnormal processing problems.

Respiratory

In the case of vapour formation use a respirator with an approved filter.

Skin/Body

Impervious clothing. Choose body protection according to the amount and concentration of the dangerous substance at the work place.

09

Physical and Chemical Properties

Appearance, physical state, melting point, boiling point, and material characteristics

Language Code
---
Physical State
liquid
Physical State Data
liquid
State Under Standard Conditions
---
Appearance
liquid
Colour
clear, colourless
Colour Intensity
---
Form
---
Odor
No data available
Odor Threshold
No data available
Ph
ca. 1,00
Melting Point
No data available
Boiling Point
No data available
Flash Point
does not flash
Freezing Point
---
Softening Point
---
Solidification Point
---
Cloud Point
---
Crystallisation Point
---
Relative Evaporation Rate
---
Evaporation Rate
No data available
Vapor Pressure
No data available
Vapor Density
---
Relative Density
No data available
Bulk Density
---
Density
1,04 g/cm3
Flammability
---
Upper Explosive Limit
No data available
Lower Explosive Limit
No data available
Explosive Limits
---
Auto Ignition Temperature
No data available
Decomposition Temperature
No data available
Solubility
---
Partition Coefficient
No data available
Solubility In Water
completely miscible
Solubility In Fat
---
Molecular Weight
---
Voc Content
---
Metal Corrosion
Corrosive to metals
Dynamic Viscosity
No data available
Kinematic Viscosity
No data available
Properties Status
---
10

Stability and Reactivity

Chemical stability, hazardous reactions, and incompatible materials

Stability

Stable under normal conditions.

Reactivity

No dangerous reaction known under conditions of normal use.

Hazardous reactions

No decomposition if stored and applied as directed.

Avoid

No data available

Incompatible

No data available

Decomposition

No data available

12

Ecological Information

Environmental toxicity, biodegradation, and bioaccumulation data

12.1 Toxicity

Product: Ecotoxicology Assessment Toxicity Data on Soil: Not expected to adsorb on soil. Other organisms relevant to the environment: No data available Components: Poly(oxy-1,2-ethanediyl), .alpha.-(phenylmethyl)-.omega.-[(1,1,3,3-tetramethylbutyl)phenoxy]-: Ecotoxicology Assessment Chronic aquatic toxicity: Harmful to aquatic life with long lasting effects. Toxicity Data on Soil: Not expected to adsorb on soil.

12.1 Toxicity

Sulpholane: Toxicity to fish : LC50 (Oryzias latipes (Orange-red killifish)): > 100 mg/l End point: mortality Exposure time: 96 h Test Type: static test Analytical monitoring: yes Method: OECD Test Guideline 203 GLP: yes Toxicity to daphnia and other aquatic invertebrates : EC50 (Daphnia magna (Water flea)): 852 mg/l End point: Immobilization Exposure time: 48 h Test Type: static test Analytical monitoring: yes Method: OECD Test Guideline 202 GLP: No information available. Toxicity to algae/aquatic plants : EC50 (Pseudokirchneriella subcapitata (green algae)): > 1.000 mg/l Exposure time: 72 h Test Type: static test Analytical monitoring: yes Method: OECD Test Guideline 201 GLP: yes NOEC (Pseudokirchneriella subcapitata (green algae)): 556 mg/l Exposure time: 72 h Test Type: static test Analytical monitoring: yes Method: OECD Test Guideline 201 GLP: yes Toxicity to microorganisms : NOEC (activated sludge): 100 mg/l Exposure time: 14 d GLP: No information available.

12.1 Toxicity

Toxicity to daphnia and other aquatic invertebrates : EC50 (Daphnia magna (Water flea)): 6,46 mg/l Exposure time: 48 h

12.1 Toxicity

Acute aquatic toxicity: Harmful to aquatic life. Chronic aquatic toxicity: This product has no known ecotoxicological effects.

12.4 Mobility in soil

Toxicity Data on Soil: Not expected to adsorb on soil.

12.7 Other adverse effects

Other organisms relevant to the environment: No data available

12.1 Toxicity

alpha-[(1,1,3,3-Tetramethylbutyl)phenyl]-omega-hydroxypoly(oxy-1,2-ethanediyl): Toxicity to fish : LC50 (Pimephales promelas (fathead minnow)): 4 - 8,9 mg/l Exposure time: 96 h Toxicity to daphnia and other aquatic invertebrates : (Daphnia magna (Water flea)): 18 - 26 mg/l Exposure time: 48 h Toxicity to microorganisms : IC50 (Bacteria): 5.000 mg/l Exposure time: 16 h

12.1 Toxicity

Sodium metaborate tetrahydrate: Toxicity to fish : LC50 (Lepomis macrochirus (Bluegill sunfish)): > 100 mg/l Exposure time: 96 h Test Type: static test Test substance: anhydrous substance

12.2 Persistence and degradability

Components:

12.2 Persistence and degradability

Components: Sulpholane: Biodegradability : Test Type: aerobic Inoculum: activated sludge Concentration: 100 mg/l Result: Not readily biodegradable. Biodegradation: 10,1 % Exposure time: 14 d Method: OECD Test Guideline 301C GLP: No information available.

12.2 Persistence and degradability

Components: alpha-[(1,1,3,3-Tetramethylbutyl)phenyl]-omega-hydroxypoly(oxy-1,2-ethanediyl): Biodegradability : Biodegradation: > 60 % Exposure time: 28 d Method: OECD Test Guideline 301B

12.2 Persistence and degradability

Sodium metaborate tetrahydrate: Biodegradability : Remarks: No data available

12.3 Bioaccumulative potential

Components:

12.3 Bioaccumulative potential

Components: Poly(oxy-1,2-ethanediyl), .alpha.-(phenylmethyl)-.omega.-[(1,1,3,3-tetramethylbutyl)phenoxy]-: Partition coefficient: n-octanol/water : Remarks: No data available

12.3 Bioaccumulative potential

Components: Sulpholane: Bioaccumulation : Species: Cyprinus carpio (Carp) Temperature: 25 °C Bioconcentration factor (BCF): < 1,3 GLP: no Partition coefficient: n-octanol/water : log Pow: < 0 (20 °C) pH: 7 Method: OECD Test Guideline 117 GLP: yes

12.3 Bioaccumulative potential

Components: Dodecan-1-ol, ethoxylated: Bioaccumulation : Species: Cyprinus carpio (Carp) Exposure time: 72 h Bioconcentration factor (BCF): 220 Partition coefficient: n-octanol/water : Remarks: No data available

12.3 Bioaccumulative potential

Components: alpha-[(1,1,3,3-Tetramethylbutyl)phenyl]-omega-hydroxypoly(oxy-1,2-ethanediyl): Bioaccumulation : Remarks: No bioaccumulation is to be expected (log Pow <= 4). Partition coefficient: n-octanol/water : log Pow: 2,7

12.3 Bioaccumulative potential

Components: Sodium metaborate tetrahydrate: Bioaccumulation : Remarks: No data available Partition coefficient: n-octanol/water : Remarks: No data available

No data available for bioaccumulation or partition coefficient.

12.4 Mobility in soil

No data available

12.5 Results of PBT and vPvB assessment

Assessment : This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.

The substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.

12.6 Other adverse effects

Product: Endocrine disrupting potential : This substance/mixture contains components considered to have endocrine disrupting properties for environment, according to REACH Article 57(f), Commission Regulation (EU) 2018/605 or Commission Delegated Regulation (EU) 2017/2100. Components: Dodecan-1-ol, ethoxylated: Additional ecological information : No data available alpha-[(1,1,3,3-Tetramethylbutyl)phenyl]-omega-hydroxypoly(oxy-1,2-ethanediyl): Endocrine disrupting potential : The substance is considered to have endocrine disrupting properties according to REACH Article 57(f) for the environment.

The product contains components considered to have endocrine disrupting properties for the environment, specifically alpha-[(1,1,3,3-Tetramethylbutyl)phenyl]-omega-hydroxypoly(oxy-1,2-ethanediyl).

13

Disposal Considerations

Waste treatment methods, disposal recommendations, and waste codes

Treatment

Wastewater contaminated with octyl/nonylphenol ethoxylates is to be collected for adequate treatment. The adequate treatment shall minimise releases of octyl/nonylphenol ethoxylates to environmental compartments as far as technically and practically possible.

Disposal

Dispose of as if it was hazardous waste. Send to a licensed waste management company.

14

Transport Information

UN numbers, shipping names, transport classes, and regulatory requirements

UN Number
1789
Shipping Name
HYDROCHLORIC ACID
Transport Class
8
Packing Group
III
15

Regulatory Information

Chemical regulations, safety assessments, and compliance status

Chemical Safety Assessment Not performed

Take note of The Management of Health and Safety at Work Regulations 1999 and Pregnant Workers Directive 92/85/EEC. Take note of Directive 94/33/EC on the protection of young people at work.

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Frequently Asked Questions

Common questions about safety, handling, and properties

What is the hazard signal word for R1?

The signal word is danger.

What is the physical form of R1?

R1 is a liquid appearing as liquid with clear, colourless color. It has no data available odor.

What is R1 used for?

For use as part of an IVD method, only

What are the hazard statements for R1?

This substance has 3 hazard statements:

  • H290: May be corrosive to metals.
  • H319: Causes serious eye irritation.
  • H360FD: May damage fertility. May damage the unborn child.

What is the melting point of R1?

The melting point is No data available and the boiling point is No data available.