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Safety Data Sheet EN

SevoFlo

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01

Identification

Product identifiers, regulatory numbers, and supplier information

Product Information

Product Name
SevoFlo
Chemical Name
Sevoflurane
Synonyms
1,1,1,3,3,3-Hexafluoro-2-(fluoromethoxy) propane; Fluoromethyl-2,2,2-trifluoro-1-(trifluoromethyl) ethyl ether

Regulatory Identifiers

CAS Number
N/A

Identified Uses

Veterinary product used as anesthetic agent

Manufacturers & Suppliers

Z

Zoetis Inc.

manufacturer

100 Campus Drive, P.O. Box 651, Florham Park, New Jersey 07932 (USA)

1-800-366-5288

Z

Zoetis Belgium S.A.

national supplier

Mercuriusstraat 20, 1930 Zaventem, Belgium

Emergency Contacts

Rocky Mountain Poison and Drug Center

1-866-531-8896

CHEMTREC

1-800-424-9300

24 hours

CHEMTREC

+1-703-527-3887

24 hours

02

Hazard Identification

GHS classification, signal word, pictograms, and hazard statements

Classified warning

Hazard Classifications

Skin Irrit. Cat. 2
Eye Irrit. Cat. 2A
STOT SE Cat. 3
Aquatic Acute Cat. 3
Aquatic Chronic Cat. 3

GHS Pictograms

GHS07 - Health hazard

GHS07

Hazard Statements

H315 Causes skin irritation
H319 Causes serious eye irritation
H336 May cause drowsiness and dizziness
H412 Harmful to aquatic life with long lasting effects

Precautionary Statements

P261 Avoid breathing dust/fume/gas/mist/vapors/spray
P264 Wash hands thoroughly after handling
P271 Use only outdoors or in a well-ventilated area
P273 Avoid release to the environment
P280 Wear protective gloves/protective clothing/eye protection/face protection
P302 + P352 IF ON SKIN: Wash with plenty of soap and water
P304 + P340 IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing
P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing
P312 Call a POISON CENTRE/doctor/physician if you feel unwell
P332 + P313 If skin irritation occurs: Get medical advice/attention
P337 + P313 If eye irritation persists: Get medical advice/attention
P362 Take off contaminated clothing and wash before reuse
P403 + P233 Store in a well-ventilated place. Keep container tightly closed
P405 Store locked up
P501 Dispose of contents/container in accordance with all local and national regulations

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03

Composition / Information on Ingredients

Chemical components, concentration ranges, and hazardous substance identification

Type substance
Chemical Name CAS Number Concentration Hazardous
Sevoflurane 28523-86-6 100% Yes

Ingredient(s) indicated as hazardous have been assessed under standards for workplace safety.

04

First Aid Measures

Emergency procedures for chemical exposure incidents

Inhalation

Remove to fresh air and keep patient at rest.

Skin contact

Remove contaminated clothing. Flush area with large amounts of water. Use soap.

Eye contact

Flush with water while holding eyelids open for at least 15 minutes.

Ingestion

Never give anything by mouth to an unconscious person. Wash out mouth with water. Do not induce vomiting unless directed by medical personnel.

Immediate Medical Attention

Seek medical attention immediately.

Medical Treatment

May reduce blood pressure. Treat symptomatically.

05

Firefighting Measures

Extinguishing media, specific hazards, and firefighter protection

Suitable media

CO2, extinguishing powder, foam, or water.

Specific hazards

Not flammable. Fine particles (such as mists) may fuel fires/explosions.

Firefighter Protection

During all fire fighting activities, wear appropriate protective equipment, including self-contained breathing apparatus.

06

Accidental Release Measures

Spill cleanup procedures, containment, and environmental protection

Emergency procedures

Ensure adequate ventilation. Personnel must wear appropriate protective equipment. Contain the source of spill if it is safe to do so. Collect spill with absorbent material. Clean spill area thoroughly. Prevent discharge to drains. For large spills: Non-essential personnel should be evacuated. Report emergency situations immediately. Clean up operations should only be undertaken by trained personnel. Shut off all electrical equipment if it is safe to do so.

Large spill

Non-essential personnel should be evacuated from affected area. Report emergency situations immediately. Clean up operations should only be undertaken by trained personnel. Provide adequate ventilation. Contain the source of the spill or leak and shut off all electrical equipment if it is safe to do so. Use absorbant material to wipe up spill and place in a sealed container for disposal. Clean spill area thoroughly. Prevent runoff from entering waterways or sewers. Prevent discharge to drains.

Environmental

Care should be taken to avoid environmental release.

Cleanup methods

Collect spill with absorbent material. Use absorbant material to wipe up spill and place in a sealed container for disposal.

Materials: absorbent material

—

Related Products

Similar products with comparable safety profiles

07

Handling and Storage

Safe handling precautions, storage conditions, and workplace requirements

Handling

When handling, use appropriate personal protective equipment (see Section 8). Use with adequate ventilation. Minimize generating airborne mists and vapors. Avoid open handling. Use local exhaust ventilation or perform work under fume hood/fume cupboard. Restrict access to work area. Avoid breathing vapor or mist. Avoid contact with eyes, skin and clothing. Wash thoroughly after handling.

Storage

Keep containers tightly closed in a cool, well-ventilated place. Store as directed by product packaging. Keep out of reach of children.

Hygiene

Wash thoroughly after handling.

08

Exposure Controls / PPE

Occupational exposure limits, engineering controls, and protective equipment

09

Physical and Chemical Properties

Appearance, physical state, melting point, boiling point, and material characteristics

Language Code
---
Physical State
Liquid
Physical State Data
liquid
State Under Standard Conditions
---
Appearance
---
Colour
Clear, colorless
Colour Intensity
---
Form
---
Odor
Ethereal
Odor Threshold
No data available.
Ph
7.0 - 7.5
Melting Point
No data available
Boiling Point
58.6C / 137.5F
Flash Point
Non-flammable
Freezing Point
---
Softening Point
---
Solidification Point
---
Cloud Point
---
Crystallisation Point
---
Relative Evaporation Rate
---
Evaporation Rate
No data available
Vapor Pressure
21 kPa @ 20C/68F; 157 mm Hg @ 20C/68F; 197 mm Hg @ 25C/77F
Vapor Density
6.94 Heavier than air
Relative Density
1.525 g/cm3 (bulk density)
Bulk Density
---
Density
---
Flammability
---
Upper Explosive Limit
No data available
Lower Explosive Limit
>25%
Explosive Limits
---
Auto Ignition Temperature
No data available
Decomposition Temperature
No data available.
Solubility
Miscible: Ethanol Ether Chloroform Benzene
Partition Coefficient
Predicted Log P 1.75 (Sevoflurane)
Solubility In Water
Slightly Soluble: Water
Solubility In Fat
---
Molecular Weight
200.5
Voc Content
---
Metal Corrosion
---
Dynamic Viscosity
---
Kinematic Viscosity
---
Properties Status
---
10

Stability and Reactivity

Chemical stability, hazardous reactions, and incompatible materials

Stability

Stable under normal conditions of use.

Reactivity

No data available

Avoid

Avoid direct sunlight, conditions that might generate heat, and sources of ignition.

Incompatible

Strong oxidizing agents, strong bases, Alkali metals

Decomposition

Thermal decomposition products may include carbon monoxide, carbon dioxide and other toxic vapors. Thermal decomposition products may include fluorine and Hydrogen fluoride.

12

Ecological Information

Environmental toxicity, biodegradation, and bioaccumulation data

12.1 Toxicity

Pimephales promelas (Fathead Minnow) LC50 43 mg/L Daphnia magna (Water Flea) EC50 48 Hours 48 mg/L Pseudokirchneriella subcapitata (Green Alga) IC50 72 Hours > 100 mg/L

12.2 Persistence and degradability

Biodegradation: (Method, Inoculum, Biodeg Study, Result, Endpoint, Duration, Classification) Sevoflurane Ready 4.4% After 28 Day(s)

Bio-accumulative Potential

Predicted Log P 1.75

Mobility in Soil

No data available

No data available

13

Disposal Considerations

Waste treatment methods, disposal recommendations, and waste codes

Treatment

Dispose of waste in accordance with all applicable laws and regulations. Member State specific and Community specific provisions must be considered. Considering the relevant known environmental and human health hazards of the material, review and implement appropriate technical and procedural waste water and waste disposal measures to prevent occupational exposure and environmental release. It is recommended that waste minimization be practiced. The best available technology should be utilized to prevent environmental releases. This may include destructive techniques for waste and wastewater.

14

Transport Information

UN numbers, shipping names, transport classes, and regulatory requirements

UN Number
3334
Shipping Name
Aviation regulated liquid, n.o.s. (sevoflurane)
Transport Class
9
Packing Group
III
15

Regulatory Information

Chemical regulations, safety assessments, and compliance status

?

Frequently Asked Questions

Common questions about safety, handling, and properties

What other names is SevoFlo known by?

SevoFlo is also known as: 1,1,1,3,3,3-Hexafluoro-2-(fluoromethoxy) propane; Fluoromethyl-2,2,2-trifluoro-1-(trifluoromethyl) ethyl ether

What is the hazard signal word for SevoFlo?

The signal word is warning.

What is the physical form of SevoFlo?

SevoFlo is a liquid with clear, colorless color. It has ethereal odor.

What is the solubility of SevoFlo?

Miscible: Ethanol Ether Chloroform Benzene

What is SevoFlo used for?

Veterinary product used as anesthetic agent

What are the hazard statements for SevoFlo?

This substance has 4 hazard statements:

  • H315: Causes skin irritation
  • H319: Causes serious eye irritation
  • H336: May cause drowsiness and dizziness
  • H412: Harmful to aquatic life with long lasting effects

What is the melting point of SevoFlo?

The melting point is No data available and the boiling point is 58.6C / 137.5F.