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Safety Data Sheet EN

DNase I, Grade II

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01

Identification

Product identifiers, regulatory numbers, and supplier information

Product Information

Product Name
DNase I, Grade II
Product Code
10104159001

Regulatory Identifiers

CAS Number
N/A

Manufacturers & Suppliers

R

Roche Diagnostics Deutschland GmbH

manufacturer

116 Sandhoferstrasse Mannheim, 68305 Germany

+496217590

Emergency Contacts

CHEMTREC

+1 703-741-5970

CHEMTREC

1-800-424-9300

02

Hazard Identification

GHS classification, signal word, pictograms, and hazard statements

Classified danger

Hazard Classifications

Combustible dust
Resp. Sens. Cat. 1
Skin Sens. Cat. 1

GHS Pictograms

GHS08 - Serious health hazard

GHS08

Hazard Statements

EUH014 May form combustible dust concentrations in air.
H317 May cause an allergic skin reaction.
H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled.

Precautionary Statements

P261 Avoid breathing dust.
P272 Contaminated work clothing must not be allowed out of the workplace.
P280 Wear protective gloves.
P285 In case of inadequate ventilation wear respiratory protection.
P302 + P352 IF ON SKIN: Wash with plenty of soap and water.
P304 + P341 IF INHALED: If breathing is difficult, remove person to fresh air and keep comfortable for breathing.
P333 + P313 If skin irritation or rash occurs: Get medical advice/ attention.
P342 + P311 If experiencing respiratory symptoms: Call a POISON CENTER/ doctor.
P363 Wash contaminated clothing before reuse.
P501 Dispose of contents/ container to an approved waste disposal plant.

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03

Composition / Information on Ingredients

Chemical components, concentration ranges, and hazardous substance identification

Type mixture
Chemical Name CAS Number Concentration Hazardous
Deoxyribonuclease 9003-98-9 70 - 90% No
04

First Aid Measures

Emergency procedures for chemical exposure incidents

Inhalation

Call a physician or poison control center immediately. Move to fresh air. If unconscious, place in recovery position and seek medical advice.

Symptoms: May cause allergy or asthma symptoms or breathing difficulties if inhaled.

Skin contact

If on skin, rinse well with water.

Symptoms: May cause an allergic skin reaction.

Eye contact

Flush eyes with water as a precaution. Remove contact lenses. Protect unharmed eye. Keep eye wide open while rinsing. If eye irritation persists, consult a specialist.

Ingestion

Keep respiratory tract clear. Do not give milk or alcoholic beverages. Never give anything by mouth to an unconscious person. If symptoms persist, call a physician.

Immediate Medical Attention

Call a physician or poison control center immediately. Take victim immediately to hospital.

Medical Treatment

The first aid procedure should be established in consultation with the doctor responsible for industrial medicine.

05

Firefighting Measures

Extinguishing media, specific hazards, and firefighter protection

Suitable media

Use extinguishing measures that are appropriate to local circumstances and the surrounding environment.

Unsuitable media

High volume water jet

Specific hazards

No information available.

Instructions

Standard procedure for chemical fires.

Firefighter Protection

Wear self-contained breathing apparatus for firefighting if necessary.

06

Accidental Release Measures

Spill cleanup procedures, containment, and environmental protection

Emergency procedures

Use personal protective equipment. Avoid dust formation. Avoid breathing dust. Ensure adequate ventilation.

Environmental

Prevent product from entering drains. Prevent further leakage or spillage if safe to do so. Local authorities should be advised if significant spillages cannot be contained.

Cleanup methods

Keep in suitable, closed containers for disposal.

Materials: suitable, closed containers

—

Related Products

Similar products with comparable safety profiles

07

Handling and Storage

Safe handling precautions, storage conditions, and workplace requirements

Handling

Avoid formation of respirable particles. Do not breathe vapors/dust. Avoid exposure - obtain special instructions before use. Avoid contact with skin and eyes. Persons susceptible to skin sensitization problems or asthma, allergies, chronic or recurrent respiratory disease should not be employed in any process in which this mixture is being used.

Storage

Keep container tightly closed in a dry and well-ventilated place.

Hygiene

Avoid contact with skin and eyes.

Fire prevention

Avoid dust formation. Provide appropriate exhaust ventilation at places where dust is formed.

08

Exposure Controls / PPE

Occupational exposure limits, engineering controls, and protective equipment

09

Physical and Chemical Properties

Appearance, physical state, melting point, boiling point, and material characteristics

Language Code
---
Physical State
solid
Physical State Data
solid
State Under Standard Conditions
---
Appearance
solid, (lyophilized)
Colour
white
Colour Intensity
---
Form
---
Odor
---
Odor Threshold
Not applicable
Ph
Not applicable
Melting Point
No data available
Boiling Point
No data available
Flash Point
does not flash
Freezing Point
---
Softening Point
---
Solidification Point
---
Cloud Point
---
Crystallisation Point
---
Relative Evaporation Rate
---
Evaporation Rate
No data available
Vapor Pressure
---
Vapor Density
---
Relative Density
No data available
Bulk Density
---
Density
---
Flammability
Sustains combustion
Upper Explosive Limit
No data available
Lower Explosive Limit
No data available
Explosive Limits
---
Auto Ignition Temperature
No data available
Decomposition Temperature
No data available
Solubility
---
Partition Coefficient
No data available
Solubility In Water
soluble
Solubility In Fat
---
Molecular Weight
---
Voc Content
---
Metal Corrosion
---
Dynamic Viscosity
Not applicable
Kinematic Viscosity
Not applicable
Properties Status
---
10

Stability and Reactivity

Chemical stability, hazardous reactions, and incompatible materials

Stability

Stable under normal conditions.

Reactivity

No dangerous reaction known under conditions of normal use.

Hazardous reactions

No dangerous reaction known under conditions of normal use. No decomposition if stored and applied as directed.

Avoid

Exposure to moisture.

Incompatible

Strong oxidizing agents

Decomposition

No decomposition if stored and applied as directed.

12

Ecological Information

Environmental toxicity, biodegradation, and bioaccumulation data

Ecotoxicity

Toxicity Data on Soil: Not expected to adsorb on soil. Other organisms relevant to the environment: No data available

No toxicity data available; substance not expected to adsorb on soil.

Persistence and degradability

12.3 Bioaccumulative potential

12.4 Mobility in soil

Toxicity Data on Soil: Not expected to adsorb on soil.

12.5 Results of PBT and vPvB assessment

12.6 Endocrine disrupting properties

12.7 Other adverse effects

Bioaccumulative potential

Components: Deoxyribonuclease: Partition coefficient: n-octanol/water Remarks: No data available

Mobility in soil

No data available

Other adverse effects

Ozone-Depletion Potential: Regulation: 40 CFR Protection of Environment; Part 82 Protection of Stratospheric Ozone - CAA Section 602 Class I Substances Remarks: This product neither contains, nor was manufactured with a Class I or Class II ODS as defined by the U.S. Clean Air Act Section 602 (40 CFR 82, Subpt. A, App.A + B).

The product does not contain or use Class I or Class II ozone-depleting substances as defined by the U.S. Clean Air Act.

13

Disposal Considerations

Waste treatment methods, disposal recommendations, and waste codes

Treatment

Can be disposed as waste water, when in compliance with local regulations.

Disposal

Send to a licensed waste management company.

14

Transport Information

UN numbers, shipping names, transport classes, and regulatory requirements

15

Regulatory Information

Chemical regulations, safety assessments, and compliance status

?

Frequently Asked Questions

Common questions about safety, handling, and properties

What is the hazard signal word for DNase I, Grade II?

The signal word is danger.

What is the physical form of DNase I, Grade II?

DNase I, Grade II is a solid appearing as solid, (lyophilized) with white color.

What are the hazard statements for DNase I, Grade II?

This substance has 3 hazard statements:

  • EUH014: May form combustible dust concentrations in air.
  • H317: May cause an allergic skin reaction.
  • H334: May cause allergy or asthma symptoms or breathing difficulties if inhaled.

What is the melting point of DNase I, Grade II?

The melting point is No data available and the boiling point is No data available.