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Safety Data Sheet EN

2-Mercaptoethanol

CAS 60-24-2

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01

Identification

Product identifiers, regulatory numbers, and supplier information

Product Information

Product Name
2-Mercaptoethanol
Product Code
M3148
Chemical Name
2-Mercaptoethanol

Regulatory Identifiers

CAS Number
60-24-2 Check regulations →

Identified Uses

Laboratory chemicals, Synthesis of substances

Uses advised against

The product is being supplied under the TSCA R&D Exemption (40 CFR Section 720.36). It is the recipient's responsibility to comply with the requirements of the R&D exemption. The product may not be used for a non-exempt commercial purpose under TSCA unless appropriate consent is granted in writing by MilliporeSigma.

Manufacturers & Suppliers

S

Sigma-Aldrich Inc.

manufacturer

3050 SPRUCE ST, ST. LOUIS MO 63103, UNITED STATES

+1 314 771-5765

Emergency Contacts

CHEMTREC

800-424-9300

24 Hours/day; 7 Days/week

CHEMTREC

+1-703-527-3887

24 Hours/day; 7 Days/week

02

Hazard Identification

GHS classification, signal word, pictograms, and hazard statements

Classified danger

Hazard Classifications

Flam. Liq. Cat. 4 H227
Acute Tox. Cat. 3 H301
Acute Tox. Cat. 3 H331
Acute Tox. Cat. 2 H310
Skin Irrit. Cat. 2 H315
Eye Dam. Cat. 1 H318
Skin Sens. Cat. 1A H317
Repr. Cat. 2 H361
STOT RE Cat. 2 H373
Aquatic Acute Cat. 1 H400
Aquatic Chronic Cat. 2 H411

GHS Pictograms

GHS05 - Corrosive

GHS05

GHS06 - Acute toxicity

GHS06

GHS07 - Health hazard

GHS07

GHS08 - Serious health hazard

GHS08

GHS09 - Environmental hazard

GHS09

Hazard Statements

H227 Combustible liquid.
H301 + H331 Toxic if swallowed or if inhaled.
H310 Fatal in contact with skin.
H315 Causes skin irritation.
H317 May cause an allergic skin reaction.
H318 Causes serious eye damage.
H361 Suspected of damaging fertility or the unborn child.
H373 May cause damage to organs (Liver, Heart) through prolonged or repeated exposure if swallowed.
H400 Very toxic to aquatic life.
H411 Toxic to aquatic life with long lasting effects.

Precautionary Statements

P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P210 Keep away from heat/ sparks/ open flames/ hot surfaces. No smoking.
P260 Do not breathe mist or vapors.
P262 Do not get in eyes, on skin, or on clothing.
P264 Wash skin thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P272 Contaminated work clothing must not be allowed out of the workplace.
P273 Avoid release to the environment.
P280 Wear protective gloves/ protective clothing/ eye protection/ face protection.
P302 + P352 IF ON SKIN: Wash with plenty of soap and water.
P304 + P340 + P311 IF INHALED: Remove person to fresh air and keep comfortable for breathing. Call a POISON CENTER/ doctor.
P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER/ doctor.
P308 + P313 IF exposed or concerned: Get medical advice/ attention.
P333 + P313 If skin irritation or rash occurs: Get medical advice/ attention.
P362 Take off contaminated clothing and wash before reuse.
P370 + P378 In case of fire: Use dry sand, dry chemical or alcohol-resistant foam to extinguish.
P391 Collect spillage.
P403 + P233 Store in a well-ventilated place. Keep container tightly closed.
P403 + P235 Store in a well-ventilated place. Keep cool.
P405 Store locked up.
P501 Dispose of contents/ container to an approved waste disposal plant.
IF SWALLOWED: Immediately call a POISON CENTER/ doctor. Rinse mouth.
IF ON SKIN: Gently wash with plenty of soap and water. Immediately call a POISON CENTER or doctor/ physician.

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03

Composition / Information on Ingredients

Chemical components, concentration ranges, and hazardous substance identification

Type substance
Chemical Name CAS Number Concentration Hazardous
Mercaptoethanol EC: 200-464-6 60-24-2 100% Yes
04

First Aid Measures

Emergency procedures for chemical exposure incidents

Inhalation

fresh air. Immediately call in physician. If breathing stops: immediately apply artificial respiration, if necessary also oxygen.

Skin contact

Take off immediately all contaminated clothing. Rinse skin with water/ shower. Call a physician immediately.

Eye contact

rinse out with plenty of water. Immediately call in ophthalmologist. Remove contact lenses.

Ingestion

give water to drink (two glasses at most). Seek medical advice immediately. In exceptional cases only, if medical care is not available within one hour, induce vomiting (only in persons who are wide awake and fully conscious), administer activated charcoal (20 - 40 g in a 10% slurry) and consult a doctor as quickly as possible.

Immediate Medical Attention

Immediately call in physician. Call a physician immediately. Immediately call in ophthalmologist. Seek medical advice immediately. consult a doctor as quickly as possible.

05

Firefighting Measures

Extinguishing media, specific hazards, and firefighter protection

Suitable media

Water, Foam, Carbon dioxide (CO2), Dry powder

Unsuitable media

For this substance/mixture no limitations of extinguishing agents are given.

Specific hazards

Combustible. Vapors are heavier than air and may spread along floors. Forms explosive mixtures with air on intense heating. Development of hazardous combustion gases or vapours possible in the event of fire.

Instructions

Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.

Firefighter Protection

Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.

06

Accidental Release Measures

Spill cleanup procedures, containment, and environmental protection

Emergency procedures

Do not breathe vapors, aerosols. Avoid substance contact. Ensure adequate ventilation. Keep away from heat and sources of ignition. Evacuate the danger area, observe emergency procedures, consult an expert.

Environmental

Do not let product enter drains.

Cleanup methods

Take up carefully with liquid-absorbent material (e.g. Chemizorb®). Dispose of properly. Clean up affected area.

Materials: liquid-absorbent material (e.g. Chemizorb®)

—

Related Products

Similar products with comparable safety profiles

07

Handling and Storage

Safe handling precautions, storage conditions, and workplace requirements

Handling

Work under hood. Do not inhale substance/mixture. Avoid generation of vapours/aerosols.

Storage

Tightly closed. Keep in a well-ventilated place. Keep locked up or in an area accessible only to qualified or authorized persons.

Hygiene

Immediately change contaminated clothing. Apply preventive skin protection. Wash hands and face after working with substance.

Fire prevention

Keep away from open flames, hot surfaces and sources of ignition.

08

Exposure Controls / PPE

Occupational exposure limits, engineering controls, and protective equipment

Hands

Full contact: Material: butyl-rubber, Minimum layer thickness: 0.7 mm, Break through time: 480 min, Material tested: Butoject® (KCL 898). Splash contact: Material: Nitrile rubber, Minimum layer thickness: 0.4 mm, Break through time: 120 min, Material tested: Camatril® (KCL 730 / Aldrich Z677442, Size M). When dissolving in or mixing with other substances and under conditions deviating from those stated in EN 16523-1 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell, Internet: www.kcl.de).

Eyes

Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Tightly fitting safety goggles

Respiratory

Recommended Filter type: Filter B-(P3). The entrepreneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer. These measures have to be properly documented. required when vapours/aerosols are generated. Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system.

Skin/Body

protective clothing

Environmental

Do not let product enter drains.

09

Physical and Chemical Properties

Appearance, physical state, melting point, boiling point, and material characteristics

Language Code
---
Physical State
liquid
Physical State Data
liquid
State Under Standard Conditions
---
Appearance
liquid, colorless
Colour
colorless
Colour Intensity
---
Form
liquid
Odor
characteristic
Odor Threshold
5.7 ppm
Ph
4.5 - 6 at 500 g/l at 20 °C (68 °F)
Melting Point
< -50 °C (< -58 °F)
Boiling Point
157 °C 315 °F
Flash Point
68 °C (154 °F) - closed cup
Freezing Point
---
Softening Point
---
Solidification Point
---
Cloud Point
---
Crystallisation Point
---
Relative Evaporation Rate
---
Evaporation Rate
---
Vapor Pressure
0.76 hPa at 20 °C (68 °F)
Vapor Density
2.70 - (Air = 1.0)
Relative Density
---
Bulk Density
---
Density
1.114 g/mL at 25 °C (77 °F)
Flammability
---
Upper Explosive Limit
18 % (V)
Lower Explosive Limit
2.3 % (V)
Explosive Limits
---
Auto Ignition Temperature
---
Decomposition Temperature
---
Solubility
---
Partition Coefficient
log Pow: -0.056 at 25 °C (77 °F) - Bioaccumulation is not expected.
Solubility In Water
soluble
Solubility In Fat
---
Molecular Weight
---
Voc Content
---
Metal Corrosion
---
Dynamic Viscosity
---
Kinematic Viscosity
---
Properties Status
---
10

Stability and Reactivity

Chemical stability, hazardous reactions, and incompatible materials

Stability

The product is chemically stable under standard ambient conditions (room temperature).

Reactivity

Forms explosive mixtures with air on intense heating. A range from approx. 15 Kelvin below the flash point is to be rated as critical.

Hazardous reactions

Violent reactions possible with: Strong oxidizing agents. A risk of explosion and/or of toxic gas formation exists with the following substances: Acids

Avoid

Strong heating.

Incompatible

Metals, Oxidizing agents, Strong oxidizing agents

Decomposition

In the event of fire: see section 5

12

Ecological Information

Environmental toxicity, biodegradation, and bioaccumulation data

12.1 Toxicity

- Toxicity to fish: static test LC50 - Leuciscus idus (Golden orfe) - 37 mg/l - 96 h (DIN 38412 T15) - Toxicity to daphnia and other aquatic invertebrates: static test EC50 - Daphnia magna (Water flea) - 0.4 mg/l - 48 h (OECD Test Guideline 202) - Toxicity to algae: static test ErC50 - Desmodesmus subspicatus (green algae) - 19 mg/l - 72 h (OECD Test Guideline 201) - Toxicity to bacteria: static test EC50 - Pseudomonas putida - 125 mg/l - 17 h (DIN 38 412 Part 8) - Toxicity to daphnia and other aquatic invertebrates (Chronic toxicity): semi-static test NOEC - Daphnia magna (Water flea) - > 0.0632 mg/l - 21 d (OECD Test Guideline 211)

12.2 Persistence and degradability

12.2 Persistence and degradability

- Biodegradability: Result: > 70 % - rapidly biodegradable Remarks: (ECHA) - Biochemical Oxygen Demand (BOD): 105 mg/g Remarks: (IUCLID) Chemical Oxygen 1.894 mg/g

12.2 Persistence and degradability

Demand (COD) Remarks: (IUCLID)

Mentions Chemical Oxygen Demand (COD) with reference to IUCLID data.

12.3 Bioaccumulative potential

Does not accumulate in organisms.

Does not accumulate in organisms.

12.4 Mobility in soil

No data available

12.5 Results of PBT and vPvB assessment

PBT/vPvB assessment not available as chemical safety assessment not required/not conducted

PBT/vPvB assessment not available as chemical safety assessment not required/not conducted

12.6 Endocrine disrupting properties

No data available

12.7 Other adverse effects

13

Disposal Considerations

Waste treatment methods, disposal recommendations, and waste codes

Treatment

Waste material must be disposed of in accordance with the national and local regulations.

Disposal

Leave chemicals in original containers. No mixing with other waste.

14

Transport Information

UN numbers, shipping names, transport classes, and regulatory requirements

UN Number
2966
Shipping Name
Thioglycol
Transport Class
6.1
Packing Group
II
15

Regulatory Information

Chemical regulations, safety assessments, and compliance status

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Frequently Asked Questions

Common questions about safety, handling, and properties

What is the hazard signal word for 2-Mercaptoethanol?

The signal word is danger.

What is the physical form of 2-Mercaptoethanol?

2-Mercaptoethanol is a liquid appearing as liquid, colorless with colorless color. It has characteristic odor.

What is 2-Mercaptoethanol used for?

Laboratory chemicals, Synthesis of substances

What are the hazard statements for 2-Mercaptoethanol?

This substance has 10 hazard statements:

  • H227: Combustible liquid.
  • H301 + H331: Toxic if swallowed or if inhaled.
  • H310: Fatal in contact with skin.
  • H315: Causes skin irritation.
  • H317: May cause an allergic skin reaction.
  • H318: Causes serious eye damage.
  • H361: Suspected of damaging fertility or the unborn child.
  • H373: May cause damage to organs (Liver, Heart) through prolonged or repeated exposure if swallowed.
  • H400: Very toxic to aquatic life.
  • H411: Toxic to aquatic life with long lasting effects.

What is the melting point of 2-Mercaptoethanol?

The melting point is < -50 °C (< -58 °F) and the boiling point is 157 °C 315 °F.