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Safety Data Sheet EN

Dimethyl sulfoxide

CAS 67-68-5

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01

Identification

Product identifiers, regulatory numbers, and supplier information

Product Information

Product Name
Dimethyl sulfoxide
Product Code
D8418

Regulatory Identifiers

CAS Number
67-68-5 Check regulations →

Identified Uses

Laboratory chemicals, Synthesis of substances

Manufacturers & Suppliers

S

Sigma-Aldrich Inc.

manufacturer

3050 SPRUCE ST ST. LOUIS MO 63103 UNITED STATES

+1 314 771-5765

Emergency Contacts

CHEMTREC

800-424-9300

24 Hours/day; 7 Days/week

CHEMTREC

+1-703-527-3887

24 Hours/day; 7 Days/week

02

Hazard Identification

GHS classification, signal word, pictograms, and hazard statements

Classified warning

Hazard Classifications

Flam. Liq. Cat. 4 H227

GHS Pictograms

Hazard Statements

H227 Combustible liquid.

Precautionary Statements

P210 Keep away from heat/ sparks/ open flames/ hot surfaces. No smoking.
P280 Wear protective gloves/ eye protection/ face protection.
P370 + P378 In case of fire: Use dry sand, dry chemical or alcohol-resistant foam to extinguish.
P403 + P235 Store in a well-ventilated place. Keep cool.
P501 Dispose of contents/ container to an approved waste disposal plant.

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03

Composition / Information on Ingredients

Chemical components, concentration ranges, and hazardous substance identification

Type substance
Chemical Name CAS Number Concentration Hazardous
dimethyl sulphoxide EC: 200-664-3 67-68-5 100% Yes
04

First Aid Measures

Emergency procedures for chemical exposure incidents

Inhalation

fresh air.

Skin contact

Take off immediately all contaminated clothing. Rinse skin with water/ shower.

Eye contact

rinse out with plenty of water. Remove contact lenses.

Ingestion

make victim drink water (two glasses at most). Consult doctor if feeling unwell.

05

Firefighting Measures

Extinguishing media, specific hazards, and firefighter protection

Suitable media

Water, Foam, Carbon dioxide (CO2), Dry powder

Unsuitable media

For this substance/mixture no limitations of extinguishing agents are given.

Specific hazards

Combustible. Vapors are heavier than air and may spread along floors. Forms explosive mixtures with air on intense heating. Development of hazardous combustion gases or vapours possible in the event of fire.

Instructions

Remove container from danger zone and cool with water. Suppress (knock down) gases/vapors/mists with a water spray jet.

Firefighter Protection

In the event of fire, wear self-contained breathing apparatus.

06

Accidental Release Measures

Spill cleanup procedures, containment, and environmental protection

Emergency procedures

Evacuate the danger area, observe emergency procedures, consult an expert.

Environmental

Do not let product enter drains.

Cleanup methods

Take up with liquid-absorbent material (e.g. Chemizorb®). Dispose of properly. Clean up affected area.

Materials: liquid-absorbent material (e.g. Chemizorb®)

—

Related Products

Similar products with comparable safety profiles

07

Handling and Storage

Safe handling precautions, storage conditions, and workplace requirements

Handling

Keep away from open flames, hot surfaces and sources of ignition. Take precautionary measures against static discharge.

Storage

Tightly closed. Store under inert gas. hygroscopic

Hygiene

Change contaminated clothing. Wash hands after working with substance.

Fire prevention

Keep away from open flames, hot surfaces and sources of ignition.

08

Exposure Controls / PPE

Occupational exposure limits, engineering controls, and protective equipment

Hands

Full contact: Material: Chloroprene, Minimum layer thickness: 0.65 mm, Break through time: 480 min, Material tested: KCL 720 Camapren®. Splash contact: Material: Latex gloves, Minimum layer thickness: 0.6 mm, Break through time: 240 min, Material tested: Lapren® (KCL 706 / Aldrich Z677558, Size M). This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN374 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell, Internet: www.kcl.de).

Eyes

Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Safety glasses

Respiratory

required when vapours/aerosols are generated. Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system.

Environmental

Do not let product enter drains.

09

Physical and Chemical Properties

Appearance, physical state, melting point, boiling point, and material characteristics

Language Code
---
Physical State
liquid
Physical State Data
liquid
State Under Standard Conditions
---
Appearance
clear, liquid
Colour
clear
Colour Intensity
---
Form
liquid
Odor
odorless
Odor Threshold
No data available
Ph
Not applicable
Melting Point
16 - 19 °C (61 - 66 °F)
Boiling Point
189 °C 372 °F
Flash Point
87 °C (189 °F) - closed cup - ASTM D 93
Freezing Point
---
Softening Point
---
Solidification Point
---
Cloud Point
---
Crystallisation Point
---
Relative Evaporation Rate
---
Evaporation Rate
No data available
Vapor Pressure
0.55 hPa at 20 °C (68 °F)
Vapor Density
2.70 - (Air = 1.0)
Relative Density
---
Bulk Density
---
Density
1.1 g/mL
Flammability
---
Upper Explosive Limit
28.5 % (V)
Lower Explosive Limit
2.6 % (V)
Explosive Limits
---
Auto Ignition Temperature
300 - 302 °C (572 - 576 °F) at 1,013 hPa
Decomposition Temperature
> 190 °C (> 374 °F) -
Solubility
---
Partition Coefficient
log Pow: -1.35 at 20 °C (68 °F) - Bioaccumulation is not expected.
Solubility In Water
completely miscible
Solubility In Fat
---
Molecular Weight
---
Voc Content
---
Metal Corrosion
---
Dynamic Viscosity
---
Kinematic Viscosity
---
Properties Status
---
10

Stability and Reactivity

Chemical stability, hazardous reactions, and incompatible materials

Stability

The product is chemically stable under standard ambient conditions (room temperature).

Reactivity

Forms explosive mixtures with air on intense heating. A range from approx. 15 Kelvin below the flash point is to be rated as critical.

Hazardous reactions

Risk of explosion with: acetylcholine, organic halides, perchlorates, Acid chlorides, nonmetallic halides, iron(III) compounds, nitrates, fluorides, chlorates, hydrides, perchloric acid, Oxides of phosphorus, Nitric acid, silver compounds, silicon compounds, silanes, acid halides. Exothermic reaction with: boron compounds, oxyhalogenic compounds, Potassium, sodium, Strong oxidizing agents, phosphorus halides, strong reducing agents, Acid chlorides, Strong acids, silver salt, nitrogen dioxide. Risk of ignition or formation of inflammable gases or vapours with: potassium permanganate

Avoid

Strong heating.

Incompatible

No data available

Decomposition

In the event of fire: see section 5

12

Ecological Information

Environmental toxicity, biodegradation, and bioaccumulation data

12.1 Toxicity

Toxicity to fish static test LC50 - Danio rerio (zebra fish) - > 25,000 mg/l - 96 h (OECD Test Guideline 203) Toxicity to daphnia and other aquatic invertebrates static test EC50 - Daphnia magna (Water flea) - 24,600 mg/l - 48 h (OECD Test Guideline 202) Toxicity to algae static test ErC50 - Pseudokirchneriella subcapitata (green algae) - 17,000 mg/l - 72 h (OECD Test Guideline 201) Toxicity to bacteria EC50 - activated sludge - 10 - 100 mg/l - 30 min (ISO 8192)

12.2 Persistence and degradability

Biodegradability aerobic - Exposure time 28 d Result: 31 % - Not readily biodegradable. (OECD Test Guideline 301D)

12.5 Results of PBT and vPvB assessment

PBT/vPvB assessment not available as chemical safety assessment not required/not conducted

PBT/vPvB assessment not available as chemical safety assessment not required/not conducted

12.6 Endocrine disrupting properties

No data available

12.7 Other adverse effects

Stability in water - 0.12 - 1.2 h at 30 °C pH 7 Remarks: Hydrolyzes readily.
13

Disposal Considerations

Waste treatment methods, disposal recommendations, and waste codes

Treatment

Waste material must be disposed of in accordance with the national and local regulations.

Disposal

Leave chemicals in original containers. No mixing with other waste.

14

Transport Information

UN numbers, shipping names, transport classes, and regulatory requirements

UN Number
1993
Shipping Name
Combustible liquid, n.o.s. (dimethyl sulphoxide)
Packing Group
III
15

Regulatory Information

Chemical regulations, safety assessments, and compliance status

?

Frequently Asked Questions

Common questions about safety, handling, and properties

What is the hazard signal word for Dimethyl sulfoxide?

The signal word is warning.

What is the physical form of Dimethyl sulfoxide?

Dimethyl sulfoxide is a liquid appearing as clear, liquid with clear color. It has odorless odor.

What is Dimethyl sulfoxide used for?

Laboratory chemicals, Synthesis of substances

What are the hazard statements for Dimethyl sulfoxide?

This substance has 1 hazard statement:

  • H227: Combustible liquid.

What is the melting point of Dimethyl sulfoxide?

The melting point is 16 - 19 °C (61 - 66 °F) and the boiling point is 189 °C 372 °F.