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Safety Data Sheet EN

Dimethyl sulfoxide

CAS 67-68-5

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01

Identification

Product identifiers, regulatory numbers, and supplier information

Product Information

Product Name
Dimethyl sulfoxide
Product Code
472301
Chemical Name
Dimethyl sulfoxide

Regulatory Identifiers

CAS Number
67-68-5 Check regulations →
REACH No.
01-2119431362-50-XXXX

Identified Uses

Laboratory chemicals, Manufacture of substances

Manufacturers & Suppliers

S

Sigma-Aldrich Chemie GmbH

manufacturer

Eschenstrasse 5, D-82024 TAUFKIRCHEN

+49 (0)89 6513-1130

Emergency Contacts

CHEMTREC Deutschland

0800 181 7059

CHEMTREC weltweit

+49 (0)696 43508409

02

Hazard Identification

GHS classification, signal word, pictograms, and hazard statements

Classified no signal word

GHS Pictograms

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03

Composition / Information on Ingredients

Chemical components, concentration ranges, and hazardous substance identification

Type substance
Chemical Name CAS Number Concentration Hazardous
Methyl sulfoxide EC: 200-664-3 67-68-5 --- No
04

First Aid Measures

Emergency procedures for chemical exposure incidents

Inhalation

After inhalation: fresh air.

Skin contact

In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with water/ shower.

Eye contact

After eye contact: rinse out with plenty of water. Remove contact lenses.

Ingestion

After swallowing: make victim drink water (two glasses at most).

Immediate Medical Attention

Consult doctor if feeling unwell.

05

Firefighting Measures

Extinguishing media, specific hazards, and firefighter protection

Suitable media

Water, Foam, Carbon dioxide (CO2), Dry powder

Unsuitable media

For this substance/mixture no limitations of extinguishing agents are given.

Specific hazards

Combustible. Vapors are heavier than air and may spread along floors. Forms explosive mixtures with air on intense heating. Development of hazardous combustion gases or vapours possible in the event of fire.

Instructions

Remove container from danger zone and cool with water. Suppress (knock down) gases/vapors/mists with a water spray jet.

Firefighter Protection

In the event of fire, wear self-contained breathing apparatus.

06

Accidental Release Measures

Spill cleanup procedures, containment, and environmental protection

Emergency procedures

Do not breathe vapors, aerosols. Keep away from heat and sources of ignition. Evacuate the danger area, observe emergency procedures, consult an expert.

Environmental

Do not let product enter drains.

Cleanup methods

Take up with liquid-absorbent material (e.g. Chemizorb®). Clean up affected area.

Materials: liquid-absorbent material (e.g. Chemizorb®)

—

Related Products

Similar products with comparable safety profiles

07

Handling and Storage

Safe handling precautions, storage conditions, and workplace requirements

Handling

Keep away from open flames, hot surfaces and sources of ignition. Take precautionary measures against static discharge. Change contaminated clothing. Wash hands after working with substance.

Storage

Tightly closed. Store under inert gas. hygroscopic

Hygiene

Change contaminated clothing. Wash hands after working with substance.

Fire prevention

Keep away from open flames, hot surfaces and sources of ignition. Take precautionary measures against static discharge.

08

Exposure Controls / PPE

Occupational exposure limits, engineering controls, and protective equipment

Hands

Full contact: Material: Chloroprene, Minimum layer thickness: 0,65 mm, Break through time: 480 min, Material tested: KCL 720 Camapren®. Splash contact: Material: Latex gloves, Minimum layer thickness: 0,6 mm, Break through time: 240 min, Material tested: Lapren® (KCL 706 / Aldrich Z677558, Size M).

Eyes

Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Safety glasses

Respiratory

Recommended Filter type: Filter A (acc. to DIN 3181) for vapours of organic compounds. The entrepreneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer. These measures have to be properly documented.

Skin/Body

This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN 16523-1 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell, Internet: www.kcl.de).

Environmental

Do not let product enter drains.

09

Physical and Chemical Properties

Appearance, physical state, melting point, boiling point, and material characteristics

Language Code
---
Physical State
clear, liquid
Physical State Data
liquid
State Under Standard Conditions
---
Appearance
---
Colour
clear
Colour Intensity
---
Form
---
Odor
odorless
Odor Threshold
---
Ph
Not applicable
Melting Point
Melting point/range: 16 - 19 °C
Boiling Point
189 °C
Flash Point
87 °C - closed cup - ASTM D 93
Freezing Point
---
Softening Point
---
Solidification Point
---
Cloud Point
---
Crystallisation Point
---
Relative Evaporation Rate
---
Evaporation Rate
---
Vapor Pressure
0,55 hPa at 20 °C
Vapor Density
---
Relative Density
No data available
Bulk Density
---
Density
1,1 g/mL
Flammability
No data available
Upper Explosive Limit
Upper explosion limit: 28,5 %(V)
Lower Explosive Limit
Lower explosion limit: 2,6 %(V)
Explosive Limits
---
Auto Ignition Temperature
300 - 302 °C at 1.013 hPa
Decomposition Temperature
> 190 °C
Solubility
---
Partition Coefficient
log Pow: -1,35 at 20 °C - Bioaccumulation is not expected.
Solubility In Water
completely miscible
Solubility In Fat
---
Molecular Weight
---
Voc Content
---
Metal Corrosion
---
Dynamic Viscosity
2,14 mPa.s at 20 °C
Kinematic Viscosity
No data available
Properties Status
---
10

Stability and Reactivity

Chemical stability, hazardous reactions, and incompatible materials

Stability

The product is chemically stable under standard ambient conditions (room temperature).

Reactivity

Forms explosive mixtures with air on intense heating. A range from approx. 15 Kelvin below the flash point is to be rated as critical.

Hazardous reactions

Risk of explosion with: acetylcholine, organic halides, perchlorates, Acid chlorides, nonmetallic halides, iron(III) compounds, nitrates, fluorides, chlorates, hydrides, perchloric acid, Oxides of phosphorus, Nitric acid, silver compounds, silicon compounds, silanes, acid halides. Exothermic reaction with: boron compounds, oxyhalogenic compounds, Potassium, sodium, Strong oxidizing agents, phosphorus halides, strong reducing agents, Acid chlorides, Strong acids, silver salt, nitrogen dioxide. Risk of ignition or formation of inflammable gases or vapours with: potassium permanganate

Avoid

Strong heating.

Incompatible

acetylcholine, organic halides, perchlorates, Acid chlorides, nonmetallic halides, iron(III) compounds, nitrates, fluorides, chlorates, hydrides, perchloric acid, Oxides of phosphorus, Nitric acid, silver compounds, silicon compounds, silanes, acid halides, boron compounds, oxyhalogenic compounds, Potassium, sodium, Strong oxidizing agents, phosphorus halides, strong reducing agents, Strong acids, silver salt, nitrogen dioxide, potassium permanganate

Decomposition

In the event of fire: see section 5

12

Ecological Information

Environmental toxicity, biodegradation, and bioaccumulation data

12.1 Toxicity

Toxicity to fish static test LC50 - Danio rerio (zebra fish) - > 25.000 mg/l - 96 h (OECD Test Guideline 203) Toxicity to daphnia and other aquatic invertebrates static test EC50 - Daphnia magna (Water flea) - 24.600 mg/l - 48 h (OECD Test Guideline 202) Toxicity to algae static test ErC50 - Pseudokirchneriella subcapitata (green algae) - 17.000 mg/l - 72 h (OECD Test Guideline 201) Toxicity to bacteria EC50 - activated sludge - 10 - 100 mg/l - 30 min (ISO 8192)

12.2 Persistence and degradability

12.2 Persistence and degradability

Biodegradability aerobic - Exposure time 28 d Result: 31 % - Not readily biodegradable. (OECD Test Guideline 301D)

12.3 Bioaccumulative potential

No data available

12.4 Mobility in soil

No data available

12.5 Results of PBT and vPvB assessment

This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.

The substance/mixture does not contain PBT or vPvB components at levels of 0.1% or higher.

12.6 Endocrine disrupting properties

**Product:** **Assessment** : The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher.

The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher.

12.7 Other adverse effects

Stability in water - 0,12 - 1,2 h at 30 °C pH 7 Remarks: Hydrolyzes readily.
13

Disposal Considerations

Waste treatment methods, disposal recommendations, and waste codes

Treatment

No data available

14

Transport Information

UN numbers, shipping names, transport classes, and regulatory requirements

15

Regulatory Information

Chemical regulations, safety assessments, and compliance status

This material safety data sheet complies with the requirements of Regulation (EC) No. 1907/2006.

Chemical Safety Assessment Not performed
?

Frequently Asked Questions

Common questions about safety, handling, and properties

What is the hazard signal word for Dimethyl sulfoxide?

The signal word is no signal word.

What is the physical form of Dimethyl sulfoxide?

Dimethyl sulfoxide is a clear, liquid with clear color. It has odorless odor.

What is Dimethyl sulfoxide used for?

Laboratory chemicals, Manufacture of substances

What is the melting point of Dimethyl sulfoxide?

The melting point is Melting point/range: 16 - 19 °C and the boiling point is 189 °C.