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Safety Data Sheet EN

Tetracycline hydrochloride

CAS 64-75-5

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01

Identification

Product identifiers, regulatory numbers, and supplier information

Product Information

Product Name
Tetracycline hydrochloride
Product Code
T4062
Chemical Name
Tetracycline hydrochloride

Regulatory Identifiers

CAS Number
64-75-5 Check regulations →

Identified Uses

Laboratory chemicals, Synthesis of substances

Uses advised against

The product is being supplied under the TSCA R&D Exemption (40 CFR Section 720.36). It is the recipient's responsibility to comply with the requirements of the R&D exemption. The product may not be used for a non-exempt commercial purpose under TSCA unless appropriate consent is granted in writing by MilliporeSigma.

Manufacturers & Suppliers

S

Sigma-Aldrich Inc.

manufacturer

3050 SPRUCE ST, ST. LOUIS MO 63103, UNITED STATES

+1 314 771-5765

Emergency Contacts

CHEMTREC

800-424-9300

24 Hours/day; 7 Days/week

CHEMTREC

+1-703-527-3887

24 Hours/day; 7 Days/week

02

Hazard Identification

GHS classification, signal word, pictograms, and hazard statements

Classified warning

Hazard Classifications

Skin Irrit. Cat. 2 H315
Eye Irrit. Cat. 2A H319
Repr. Cat. 2 H361
STOT SE Cat. 3 H335
Aquatic Acute Cat. 1 H400
Aquatic Chronic Cat. 2 H411

GHS Pictograms

GHS07 - Health hazard

GHS07

GHS08 - Serious health hazard

GHS08

GHS09 - Environmental hazard

GHS09

Hazard Statements

H315 Causes skin irritation.
H319 Causes serious eye irritation.
H335 May cause respiratory irritation.
H361 Suspected of damaging fertility or the unborn child.
H400 Very toxic to aquatic life.
H411 Toxic to aquatic life with long lasting effects.

Precautionary Statements

P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P261 Avoid breathing dust.
P264 Wash skin thoroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P273 Avoid release to the environment.
P280 Wear protective gloves/ protective clothing/ eye protection/ face protection.
P302 + P352 IF ON SKIN: Wash with plenty of soap and water.
P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P308 + P313 IF exposed or concerned: Get medical advice/ attention.
P332 + P313 If skin irritation occurs: Get medical advice/ attention.
P337 + P313 If eye irritation persists: Get medical advice/ attention.
P362 Take off contaminated clothing and wash before reuse.
P391 Collect spillage.
P403 + P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/ container to an approved waste disposal plant.
IF INHALED: Remove person to fresh air and keep comfortable for breathing. Call a POISON CENTER/ doctor if you feel unwell.

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03

Composition / Information on Ingredients

Chemical components, concentration ranges, and hazardous substance identification

Type substance
Chemical Name CAS Number Concentration Hazardous
Tetracycline hydrochloride EC: 200-593-8 64-75-5 100% Yes
04

First Aid Measures

Emergency procedures for chemical exposure incidents

Inhalation

fresh air. Call in physician.

Skin contact

Take off immediately all contaminated clothing. Rinse skin with water/ shower. Consult a physician.

Eye contact

rinse out with plenty of water. Call in ophthalmologist. Remove contact lenses.

Ingestion

immediately make victim drink water (two glasses at most). Consult a physician.

05

Firefighting Measures

Extinguishing media, specific hazards, and firefighter protection

Suitable media

Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.

Specific hazards

Combustible. Development of hazardous combustion gases or vapours possible in the event of fire.

Instructions

Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.

Firefighter Protection

Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.

06

Accidental Release Measures

Spill cleanup procedures, containment, and environmental protection

Emergency procedures

Avoid inhalation of dusts. Avoid substance contact. Ensure adequate ventilation. Evacuate the danger area, observe emergency procedures, consult an expert.

Environmental

Do not let product enter drains.

Cleanup methods

Take up dry. Clean up affected area.

—

Related Products

Similar products with comparable safety profiles

07

Handling and Storage

Safe handling precautions, storage conditions, and workplace requirements

Handling

For precautions see section 2.2.

Storage

Tightly closed. Dry.

08

Exposure Controls / PPE

Occupational exposure limits, engineering controls, and protective equipment

Hands

Splash contact: Material: Nitrile rubber, Minimum layer thickness: 0.11 mm, Break through time: 480 min, Material tested: KCL 741 Dermatril® L. Full contact: Material: Nitrile rubber, Minimum layer thickness: 0.11 mm, Break through time: 480 min, Material tested: KCL 741 Dermatril® L. This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN 16523-1 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell, Internet: www.kcl.de).

Eyes

Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Safety glasses

Respiratory

For nuisance exposures use type P95 (US) or type P1 (EU EN 143) particle respirator. For higher level protection use type OV/AG/P99 (US) or type ABEK-P2 (EU EN 143) respirator cartridges. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).

Skin/Body

protective clothing

Environmental

Do not let product enter drains.

09

Physical and Chemical Properties

Appearance, physical state, melting point, boiling point, and material characteristics

Language Code
---
Physical State
Crystalline powder
Physical State Data
solid
State Under Standard Conditions
---
Appearance
Crystalline powder, yellow
Colour
yellow
Colour Intensity
---
Form
Crystalline powder
Odor
No data available
Odor Threshold
No data available
Ph
No data available
Melting Point
220 - 223 °C (428 - 433 °F) - lit.
Boiling Point
---
Flash Point
Not applicable
Freezing Point
---
Softening Point
---
Solidification Point
---
Cloud Point
---
Crystallisation Point
---
Relative Evaporation Rate
---
Evaporation Rate
---
Vapor Pressure
---
Vapor Density
---
Relative Density
---
Bulk Density
---
Density
---
Flammability
---
Upper Explosive Limit
---
Lower Explosive Limit
---
Explosive Limits
---
Auto Ignition Temperature
---
Decomposition Temperature
214 °C (417 °F) -
Solubility
---
Partition Coefficient
---
Solubility In Water
soluble
Solubility In Fat
---
Molecular Weight
---
Voc Content
---
Metal Corrosion
---
Dynamic Viscosity
---
Kinematic Viscosity
---
Properties Status
---
10

Stability and Reactivity

Chemical stability, hazardous reactions, and incompatible materials

Stability

The product is chemically stable under standard ambient conditions (room temperature).

Reactivity

The following applies in general to flammable organic substances and mixtures: in correspondingly fine distribution, when whirled up a dust explosion potential may generally be assumed.

Hazardous reactions

Caution! In contact with nitrites, nitrates, nitrous acid possible liberation of nitrosamines! Violent reactions possible with: Strong oxidizing agents

Avoid

no information available

Incompatible

No data available

Decomposition

In the event of fire: see section 5

12

Ecological Information

Environmental toxicity, biodegradation, and bioaccumulation data

12.1 Toxicity

Toxicity to fish LC50 - Salvelinus namaycush (Lake trout, siscowet) - 220 mg/l - 96 h (US-EPA) Toxicity to daphnia and other aquatic invertebrates static test EC50 - Daphnia magna (Water flea) - > 340 mg/l - 48 h (OECD Test Guideline 202) Remarks: (in analogy to similar products) The value is given in analogy to the following substances: Tetracycline

12.1 Toxicity

Toxicity to algae static test ErC50 - Pseudokirchneriella subcapitata (green algae) - 1 mg/l - 72 h (OECD Test Guideline 201) Remarks: (in analogy to similar products) The value is given in analogy to the following substances: Tetracycline

12.1 Toxicity

static test NOEC - Pseudokirchneriella subcapitata (green algae) - 0.5 mg/l - 72 h (OECD Test Guideline 201) Remarks: (in analogy to similar products) The value is given in analogy to the following substances: Tetracycline

12.2 Persistence and degradability

Biodegradability aerobic - Exposure time 28 d Result: 0 % - Not readily biodegradable. (OECD Test Guideline 301B) Remarks: (in analogy to similar compounds) The value is given in analogy to the following substances: Tetracycline

12.3 Bioaccumulative potential

No data available

No data available

12.4 Mobility in soil

No data available

No data available

12.5 Results of PBT and vPvB assessment

PBT/vPvB assessment not available as chemical safety assessment not required/not conducted

PBT/vPvB assessment not available as chemical safety assessment not required/not conducted

12.6 Endocrine disrupting properties

No data available

12.7 Other adverse effects

No data available
13

Disposal Considerations

Waste treatment methods, disposal recommendations, and waste codes

Treatment

Waste material must be disposed of in accordance with the national and local regulations.

Disposal

Leave chemicals in original containers.

14

Transport Information

UN numbers, shipping names, transport classes, and regulatory requirements

UN Number
3077
Shipping Name
ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S. (Tetracycline hydrochloride)
Transport Class
9
Packing Group
III
15

Regulatory Information

Chemical regulations, safety assessments, and compliance status

?

Frequently Asked Questions

Common questions about safety, handling, and properties

What is the hazard signal word for Tetracycline hydrochloride?

The signal word is warning.

What is the physical form of Tetracycline hydrochloride?

Tetracycline hydrochloride is a crystalline powder appearing as crystalline powder, yellow with yellow color. It has no data available odor.

What is Tetracycline hydrochloride used for?

Laboratory chemicals, Synthesis of substances

What are the hazard statements for Tetracycline hydrochloride?

This substance has 6 hazard statements:

  • H315: Causes skin irritation.
  • H319: Causes serious eye irritation.
  • H335: May cause respiratory irritation.
  • H361: Suspected of damaging fertility or the unborn child.
  • H400: Very toxic to aquatic life.
  • H411: Toxic to aquatic life with long lasting effects.

What is the melting point of Tetracycline hydrochloride?

The melting point is 220 - 223 °C (428 - 433 °F) - lit. .