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Safety Data Sheet EN

4-Hydroxyphenylacetic acid

CAS 156-38-7

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01

Identification

Product identifiers, regulatory numbers, and supplier information

Product Information

Product Name
4-Hydroxyphenylacetic acid
Product Code
H50004
Chemical Name
4-Hydroxyphenylacetic acid

Regulatory Identifiers

CAS Number
156-38-7 Check regulations →

Identified Uses

Laboratory chemicals, Synthesis of substances

Uses advised against

The product is being supplied under the TSCA R&D Exemption (40 CFR Section 720.36). It is the recipient's responsibility to comply with the requirements of the R&D exemption. The product may not be used for a non-exempt commercial purpose under TSCA unless appropriate consent is granted in writing by MilliporeSigma.

Manufacturers & Suppliers

S

Sigma-Aldrich Inc.

manufacturer

3050 SPRUCE ST ST. LOUIS MO 63103 UNITED STATES

+1 314 771-5765

Emergency Contacts

CHEMTREC

800-424-9300

24 Hours/day; 7 Days/week

CHEMTREC

+1-703-527-3887

24 Hours/day; 7 Days/week

02

Hazard Identification

GHS classification, signal word, pictograms, and hazard statements

Classified warning

Hazard Classifications

Skin Irrit. Cat. 2
Eye Irrit. Cat. 2A
STOT SE Cat. 3

GHS Pictograms

GHS07 - Health hazard

GHS07

Hazard Statements

H315 Causes skin irritation.
H319 Causes serious eye irritation.
H335 May cause respiratory irritation.

Precautionary Statements

P261 Avoid breathing dust.
P264 Wash skin thoroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/ eye protection/ face protection.
P302 + P352 IF ON SKIN: Wash with plenty of water.
P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P332 + P313 If skin irritation occurs: Get medical advice/ attention.
P337 + P313 If eye irritation persists: Get medical advice/ attention.
P403 + P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/ container to an approved waste disposal plant.
IF INHALED: Remove person to fresh air and keep comfortable for breathing. Call a POISON CENTER/ doctor if you feel unwell.

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03

Composition / Information on Ingredients

Chemical components, concentration ranges, and hazardous substance identification

Type substance
Chemical Name CAS Number Concentration Hazardous
p-Hydroxyphenylacetic acid 156-38-7 80 - 100% No
04

First Aid Measures

Emergency procedures for chemical exposure incidents

Inhalation

fresh air.

Skin contact

Take off immediately all contaminated clothing. Rinse skin with water/ shower.

Eye contact

rinse out with plenty of water. Call in ophthalmologist. Remove contact lenses.

Ingestion

immediately make victim drink water (two glasses at most). Consult a physician.

05

Firefighting Measures

Extinguishing media, specific hazards, and firefighter protection

Suitable media

Water, Foam, Carbon dioxide (CO2), Dry powder

Unsuitable media

For this substance/mixture no limitations of extinguishing agents are given.

Specific hazards

Combustible. Development of hazardous combustion gases or vapours possible in the event of fire.

Instructions

No data available

Firefighter Protection

Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.

06

Accidental Release Measures

Spill cleanup procedures, containment, and environmental protection

Emergency procedures

Avoid inhalation of dusts. Avoid substance contact. Ensure adequate ventilation. Evacuate the danger area, observe emergency procedures, consult an expert.

Environmental

Do not let product enter drains.

Cleanup methods

Take up dry. Clean up affected area.

—

Related Products

Similar products with comparable safety profiles

07

Handling and Storage

Safe handling precautions, storage conditions, and workplace requirements

Handling

For precautions see section 2.2.

Storage

Tightly closed. Dry.

08

Exposure Controls / PPE

Occupational exposure limits, engineering controls, and protective equipment

Engineering

No data available

Hands

Material : Nitrile rubber, Break through time : 480 min, Glove thickness : 0.11 mm, Protective index : Full contact, Manufacturer : KCL 741 Dermatril® L; Material : Nitrile rubber, Break through time : 480 min, Glove thickness : 0.11 mm, Protective index : Splash contact, Manufacturer : KCL 741 Dermatril® L; Remarks : This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN 16523-1 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell, Internet: www.kcl.de).

Eyes

Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Safety glasses

Respiratory

required when dusts are generated. Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system. Recommended Filter type: Filter type P2. The entrepreneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer. These measures have to be properly documented.

Skin/Body

protective clothing

09

Physical and Chemical Properties

Appearance, physical state, melting point, boiling point, and material characteristics

Language Code
---
Physical State
solid
Physical State Data
solid
State Under Standard Conditions
---
Appearance
powder
Colour
beige
Colour Intensity
---
Form
---
Odor
---
Odor Threshold
---
Ph
---
Melting Point
298 - 304 °F / 148 - 151 °C
Boiling Point
---
Flash Point
---
Freezing Point
---
Softening Point
---
Solidification Point
---
Cloud Point
---
Crystallisation Point
---
Relative Evaporation Rate
---
Evaporation Rate
---
Vapor Pressure
---
Vapor Density
---
Relative Density
---
Bulk Density
---
Density
---
Flammability
---
Upper Explosive Limit
---
Lower Explosive Limit
---
Explosive Limits
---
Auto Ignition Temperature
---
Decomposition Temperature
---
Solubility
---
Partition Coefficient
---
Solubility In Water
---
Solubility In Fat
---
Molecular Weight
152.15 g/mol
Voc Content
---
Metal Corrosion
---
Dynamic Viscosity
---
Kinematic Viscosity
---
Properties Status
---
10

Stability and Reactivity

Chemical stability, hazardous reactions, and incompatible materials

Stability

The product is chemically stable under standard ambient conditions (room temperature).

Reactivity

The following applies in general to flammable organic substances and mixtures: in correspondingly fine distribution, when whirled up a dust explosion potential may generally be assumed.

Hazardous reactions

Violent reactions possible with: - Oxidizing agents - Bases - Acid anhydrides - Acid chlorides

Avoid

no information available

Incompatible

No data available

Decomposition

In the event of fire: see section 5

12

Ecological Information

Environmental toxicity, biodegradation, and bioaccumulation data

Ecotoxicity

Components: p-Hydroxyphenylacetic acid: Toxicity to fish : Remarks: No data available

Persistence and degradability

Components: p-Hydroxyphenylacetic acid: Biodegradability : Remarks: No data available

Bioaccumulative potential

Components: p-Hydroxyphenylacetic acid: Bioaccumulation : Remarks: No data available

Mobility in soil

Components: p-Hydroxyphenylacetic acid: Stability in soil : Remarks: No data available

Other adverse effects

Product: Ozone-Depletion Potential : Regulation: 40 CFR Protection of Environment; Part 82 Protection of Stratospheric Ozone - CAA Section 602 Class I Substances Remarks: This product neither contains, nor was manufactured with a Class I or Class II ODS as defined by the U.S. Clean Air Act Section 602 (40 CFR 82, Subpt. A, App.A + B).

The product does not contain, nor was it manufactured with, Class I or Class II ozone-depleting substances as defined by the U.S. Clean Air Act Section 602.

13

Disposal Considerations

Waste treatment methods, disposal recommendations, and waste codes

Treatment

Leave chemicals in original containers. No mixing with other waste.

Disposal

Waste material must be disposed of in accordance with the national and local regulations.

14

Transport Information

UN numbers, shipping names, transport classes, and regulatory requirements

15

Regulatory Information

Chemical regulations, safety assessments, and compliance status

?

Frequently Asked Questions

Common questions about safety, handling, and properties

What is the hazard signal word for 4-Hydroxyphenylacetic acid?

The signal word is warning.

What is the physical form of 4-Hydroxyphenylacetic acid?

4-Hydroxyphenylacetic acid is a solid appearing as powder with beige color.

What is 4-Hydroxyphenylacetic acid used for?

Laboratory chemicals, Synthesis of substances

What are the hazard statements for 4-Hydroxyphenylacetic acid?

This substance has 3 hazard statements:

  • H315: Causes skin irritation.
  • H319: Causes serious eye irritation.
  • H335: May cause respiratory irritation.

What is the melting point of 4-Hydroxyphenylacetic acid?

The melting point is 298 - 304 °F / 148 - 151 °C .