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Safety Data Sheet EN

Piperidine

CAS 110-89-4

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01

Identification

Product identifiers, regulatory numbers, and supplier information

Product Information

Product Name
Piperidine
Product Code
104094

Regulatory Identifiers

CAS Number
110-89-4 Check regulations →

Identified Uses

Laboratory chemicals, Synthesis of substances

Manufacturers & Suppliers

S

Sigma-Aldrich Inc.

manufacturer

3050 SPRUCE ST, ST. LOUIS MO 63103, UNITED STATES

+1 314 771-5765

Emergency Contacts

CHEMTREC

800-424-9300

24 Hours/day; 7 Days/week

CHEMTREC

+1-703-527-3887

24 Hours/day; 7 Days/week

02

Hazard Identification

GHS classification, signal word, pictograms, and hazard statements

Classified danger

Hazard Classifications

Flam. Liq. Cat. 2 H225
Acute Tox. Cat. 4 H302
Acute Tox. Cat. 3 H331
Acute Tox. Cat. 3 H311
Skin Corr. Cat. 1B H314
Eye Dam. Cat. 1 H318
Aquatic Acute Cat. 3 H402

GHS Pictograms

GHS02 - Flammable

GHS02

GHS05 - Corrosive

GHS05

GHS06 - Acute toxicity

GHS06

Hazard Statements

H225 Highly flammable liquid and vapor.
H302 Harmful if swallowed.
H311 + H331 Toxic in contact with skin or if inhaled.
H314 Causes severe skin burns and eye damage.
H402 Harmful to aquatic life.

Precautionary Statements

P210 Keep away from heat/ sparks/ open flames/ hot surfaces. No smoking.
P233 Keep container tightly closed.
P240 Ground/bond container and receiving equipment.
P241 Use explosion-proof electrical/ ventilating/ lighting/ equipment.
P242 Use only non-sparking tools.
P243 Take precautionary measures against static discharge.
P261 Avoid breathing dust/ fume/ gas/ mist/ vapors/ spray.
P264 Wash skin thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P273 Avoid release to the environment.
P280 Wear protective gloves/ protective clothing/ eye protection/ face protection.
P301 + P330 + P331 IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P303 + P361 + P353 IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/ shower.
P304 + P340 + P310 IF INHALED: Remove person to fresh air and keep comfortable for breathing. Immediately call a POISON CENTER/ doctor.
P310 Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER/ doctor.
P362 Take off contaminated clothing and wash before reuse.
P370 + P378 In case of fire: Use dry sand, dry chemical or alcohol-resistant foam to extinguish.
P403 + P233 Store in a well-ventilated place. Keep container tightly closed.
P403 + P235 Store in a well-ventilated place. Keep cool.
P405 Store locked up.
P501 Dispose of contents/ container to an approved waste disposal plant.
IF SWALLOWED: Call a POISON CENTER/ doctor if you feel unwell. Rinse mouth.
IF IN EYES: Rinse cautiously with water for several minutes.

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03

Composition / Information on Ingredients

Chemical components, concentration ranges, and hazardous substance identification

Type substance
Chemical Name CAS Number Concentration Hazardous
Piperidine EC: 203-813-0 110-89-4 100% Yes
04

First Aid Measures

Emergency procedures for chemical exposure incidents

Inhalation

fresh air. Immediately call in physician. If breathing stops: immediately apply artificial respiration, if necessary also oxygen.

Skin contact

Take off immediately all contaminated clothing. Rinse skin with water/ shower. Call a physician immediately.

Eye contact

rinse out with plenty of water. Immediately call in ophthalmologist. Remove contact lenses.

Ingestion

make victim drink water (two glasses at most), avoid vomiting (risk of perforation). Pulmonary failure possible after aspiration of vomit. Call a physician immediately. Do not attempt to neutralise.

Symptoms: Pulmonary failure possible after aspiration of vomit.

Immediate Medical Attention

Immediately call in physician. Call a physician immediately. Immediately call in ophthalmologist. Call a physician immediately.

05

Firefighting Measures

Extinguishing media, specific hazards, and firefighter protection

Suitable media

Carbon dioxide (CO2) Foam Dry powder

Unsuitable media

For this substance/mixture no limitations of extinguishing agents are given.

Specific hazards

Combustible. Pay attention to flashback. Vapors are heavier than air and may spread along floors. Development of hazardous combustion gases or vapours possible in the event of fire. Forms explosive mixtures with air at ambient temperatures.

Instructions

Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.

Firefighter Protection

Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.

06

Accidental Release Measures

Spill cleanup procedures, containment, and environmental protection

Emergency procedures

Do not breathe vapors, aerosols. Avoid substance contact. Ensure adequate ventilation. Keep away from heat and sources of ignition. Evacuate the danger area, observe emergency procedures, consult an expert.

Environmental

Do not let product enter drains. Risk of explosion.

Cleanup methods

Take up carefully with liquid-absorbent material (e.g. Chemizorb®). Clean up affected area.

Materials: liquid-absorbent material (e.g. Chemizorb®)

—

Related Products

Similar products with comparable safety profiles

07

Handling and Storage

Safe handling precautions, storage conditions, and workplace requirements

Handling

Work under hood. Do not inhale substance/mixture. Avoid generation of vapours/aerosols.

Storage

Keep container tightly closed in a dry and well-ventilated place. Keep away from heat and sources of ignition. Keep locked up or in an area accessible only to qualified or authorized persons.

Hygiene

Immediately change contaminated clothing. Apply preventive skin protection. Wash hands and face after working with substance.

Fire prevention

Keep away from open flames, hot surfaces and sources of ignition. Take precautionary measures against static discharge.

08

Exposure Controls / PPE

Occupational exposure limits, engineering controls, and protective equipment

Hands

Full contact: Material: butyl-rubber, Minimum layer thickness: 0.7 mm, Break through time: 480 min, Material tested: Butoject® (KCL 898). Splash contact: Material: Nitrile rubber, Minimum layer thickness: 0.4 mm, Break through time: 120 min, Material tested: Camatril® (KCL 730 / Aldrich Z677442, Size M). This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN374 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell, Internet: www.kcl.de).

Eyes

Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Tightly fitting safety goggles

Respiratory

required when vapours/aerosols are generated. Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system.

Skin/Body

Flame retardant antistatic protective clothing.

Environmental

Do not let product enter drains. Risk of explosion.

09

Physical and Chemical Properties

Appearance, physical state, melting point, boiling point, and material characteristics

Language Code
---
Physical State
liquid
Physical State Data
liquid
State Under Standard Conditions
---
Appearance
Form: clear, liquid Color: colorless
Colour
colorless
Colour Intensity
---
Form
clear, liquid
Odor
amine-like
Odor Threshold
Do not attempt to smell the product as it is hazardous.
Ph
12.6 at 100 g/l at 20 °C (68 °F)
Melting Point
Melting point/range: -13 °C (9 °F) - lit.
Boiling Point
106 °C 223 °F - lit.
Flash Point
16 °C (61 °F) - closed cup
Freezing Point
---
Softening Point
---
Solidification Point
---
Cloud Point
---
Crystallisation Point
---
Relative Evaporation Rate
---
Evaporation Rate
---
Vapor Pressure
19.58 hPa at 20 °C (68 °F) - OECD Test Guideline 104
Vapor Density
2.94 - (Air = 1.0)
Relative Density
---
Bulk Density
---
Density
0.862 g/cm³ at 20 °C (68 °F) - lit.
Flammability
---
Upper Explosive Limit
10.3 % (V)
Lower Explosive Limit
1.5 % (V)
Explosive Limits
---
Auto Ignition Temperature
---
Decomposition Temperature
> 100 °C (> 212 °F) -
Solubility
---
Partition Coefficient
log Pow: 0.64 - 0.7 at 20 °C (68 °F) - - Bioaccumulation is not expected.
Solubility In Water
miscible
Solubility In Fat
---
Molecular Weight
---
Voc Content
---
Metal Corrosion
---
Dynamic Viscosity
---
Kinematic Viscosity
1.77 mm²/s at 20 °C (68 °F) - OECD Test Guideline 114 - 1.23 mm²/s at 40 °C (104 °F) - OECD Test Guideline 114 -
Properties Status
---
10

Stability and Reactivity

Chemical stability, hazardous reactions, and incompatible materials

Stability

The product is chemically stable under standard ambient conditions (room temperature).

Reactivity

Vapors may form explosive mixture with air.

Hazardous reactions

Caution! In contact with nitrites, nitrates, nitrous acid possible liberation of nitrosamines! Risk of explosion with: dicyanofurazan, N-nitrosoacetanilide, N-perchlorylpiperidine. Exothermic reaction with: Strong oxidizing agents, fire-promoting substances

Avoid

Warming.

Incompatible

Strong oxidizing agents

Decomposition

In the event of fire: see section 5

12

Ecological Information

Environmental toxicity, biodegradation, and bioaccumulation data

12.1 Toxicity

Toxicity to fish static test LC50 - Leuciscus idus (Golden orfe) - 68.12 mg/l - 96 h (DIN 38412) Toxicity to daphnia and other aquatic invertebrates static test EC50 - Daphnia magna (Water flea) - 19 mg/l - 48 h (OECD Test Guideline 202) Toxicity to algae static test ErC50 - Desmodesmus subspicatus (green algae) - 106 mg/l - 72 h (Regulation (EC) No. 440/2008, Annex, C.3) Toxicity to bacteria static test EC50 - activated sludge - > 1,000 mg/l - 0.5 h (OECD Test Guideline 209)

12.2 Persistence and degradability

12.2 Persistence and degradability

12.2 Persistence and degradability

Biodegradability aerobic - Exposure time 14 d Result: 100 % - Readily biodegradable. (OECD Test Guideline 301C)

12.3 Bioaccumulative potential

No data available

12.4 Mobility in soil

No data available

12.5 Results of PBT and vPvB assessment

PBT/vPvB assessment not available as chemical safety assessment not required/not conducted

PBT/vPvB assessment not available as chemical safety assessment not required/not conducted

12.6 Endocrine disrupting properties

No data available

12.7 Other adverse effects

No data available
13

Disposal Considerations

Waste treatment methods, disposal recommendations, and waste codes

Treatment

Waste material must be disposed of in accordance with the national and local regulations.

Disposal

Leave chemicals in original containers. No mixing with other waste.

14

Transport Information

UN numbers, shipping names, transport classes, and regulatory requirements

UN Number
2401
Shipping Name
Piperidine
Transport Class
8 (3)
Packing Group
I
15

Regulatory Information

Chemical regulations, safety assessments, and compliance status

?

Frequently Asked Questions

Common questions about safety, handling, and properties

What is the hazard signal word for Piperidine?

The signal word is danger.

What is the physical form of Piperidine?

Piperidine is a liquid appearing as form: clear, liquid color: colorless with colorless color. It has amine-like odor.

What is Piperidine used for?

Laboratory chemicals, Synthesis of substances

What are the hazard statements for Piperidine?

This substance has 5 hazard statements:

  • H225: Highly flammable liquid and vapor.
  • H302: Harmful if swallowed.
  • H311 + H331: Toxic in contact with skin or if inhaled.
  • H314: Causes severe skin burns and eye damage.
  • H402: Harmful to aquatic life.

What is the melting point of Piperidine?

The melting point is Melting point/range: -13 °C (9 °F) - lit. and the boiling point is 106 °C 223 °F - lit..