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Safety Data Sheet EN

Ketoconazole

CAS 65277-42-1
EC 265-667-4

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01

Identification

Product identifiers, regulatory numbers, and supplier information

Product Information

Product Name
Ketoconazole
Product Code
J63367
Chemical Name
(±)-cis-1-Acetyl-4-(4-[(2-[2,4-dichlorophenyl]-2-[1H-imidazol-1-ylmethyl]-1,3-dioxolan-4-yl)-methoxy]phenyl)piperazine

Regulatory Identifiers

CAS Number
65277-42-1 Check regulations →
EC Number
265-667-4 Check regulations →

Identified Uses

SU24 Scientific research and development

Manufacturers & Suppliers

Alfa Aesar Thermo Fisher Scientific Chemicals, Inc. logo

Alfa Aesar Thermo Fisher Scientific Chemicals, Inc.

manufacturer

30 Bond Street, Ward Hill, MA 01835-8099

800-343-0660

http://www.alfa.com

Emergency Contacts

Emergency Contact

(800) 343-0660

During normal business hours (Monday-Friday, 8am-7pm EST)

Carechem 24

(866) 928-0789

After normal business hours

02

Hazard Identification

GHS classification, signal word, pictograms, and hazard statements

Classified danger

Hazard Classifications

Acute Tox. Cat. 3 H301
Repr. Cat. 1B H360
STOT RE Cat. 2 H373

GHS Pictograms

GHS06 - Acute toxicity

GHS06

GHS08 - Serious health hazard

GHS08

Hazard Statements

H301 Toxic if swallowed.
H360 May damage fertility or the unborn child.
H373 May cause damage to the kidneys, the liver, the reproductive system and the endocrine system through prolonged or repeated exposure.

Precautionary Statements

P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P281 Use personal protective equipment as required.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER/ doctor/ ...
P308+P313 IF exposed or concerned: Get medical advice/attention.
P405 Store locked up.
P501 Dispose of contents/container in accordance with local/regional/national/international regulations.

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03

Composition / Information on Ingredients

Chemical components, concentration ranges, and hazardous substance identification

Type substance

Chemical characterization: Substances

Chemical Name CAS Number Concentration Hazardous
(±)-cis-1-Acetyl-4-(4-[(2-[2,4-dichlorophenyl]-2-[1H-imidazol-1-ylmethyl]-1,3-dioxolan-4-yl)-methoxy]phenyl)piperazine EC: 265-667-4 65277-42-1 --- No
04

First Aid Measures

Emergency procedures for chemical exposure incidents

Inhalation

Supply fresh air. If required, provide artificial respiration. Keep patient warm. Seek immediate medical advice.

Skin contact

Immediately wash with water and soap and rinse thoroughly. Seek immediate medical advice.

Eye contact

Rinse opened eye for several minutes under running water. Then consult a doctor.

Ingestion

Do not induce vomiting; immediately call for medical help.

Related Substances

Similar chemicals with comparable safety profiles

08

Exposure Controls / PPE

Occupational exposure limits, engineering controls, and protective equipment

Engineering

Properly operating chemical fume hood designed for hazardous chemicals and having an average face velocity of at least 100 feet per minute.

Hands

Impervious gloves. Check protective gloves prior to each use for their proper condition. The selection of suitable gloves not only depends on the material, but also on quality. Quality will vary from manufacturer to manufacturer. Material of gloves Nitrile rubber, NBR. Penetration time of glove material (in minutes) Not determined.

Eyes

Safety glasses

Respiratory

Use suitable respirator when high concentrations are present. Recommended filter device for short term use: Use a respirator with type P100 (USA) or P3 (EN 143) cartridges as a backup to engineering controls. Risk assessment should be performed to determine if air-purifying respirators are appropriate. Only use equipment tested and approved under appropriate government standards.

Skin/Body

Protective work clothing.

09

Physical and Chemical Properties

Appearance, physical state, melting point, boiling point, and material characteristics

Physical State
---
Physical State Data
solid
State Under Standard Conditions
---
Appearance
---
Colour
White
Colour Intensity
---
Form
Powder
Odor
Not determined
Odor Threshold
Not determined.
Ph
Not applicable.
Melting Point
Not determined
Boiling Point
Not determined
Flash Point
---
Freezing Point
---
Softening Point
---
Solidification Point
---
Cloud Point
---
Crystallisation Point
---
Relative Evaporation Rate
---
Evaporation Rate
Not applicable.
Vapor Pressure
Not applicable.
Vapor Density
Not applicable.
Relative Density
Not determined.
Bulk Density
---
Density
Not determined
Flammability
Not determined.
Upper Explosive Limit
Not determined
Lower Explosive Limit
Not determined
Explosive Limits
---
Auto Ignition Temperature
Not determined.
Decomposition Temperature
Not determined
Solubility
---
Partition Coefficient
Not determined.
Solubility In Water
Not determined
Solubility In Fat
---
Molecular Weight
---
Voc Content
---
Metal Corrosion
---
Dynamic Viscosity
Not applicable.
Kinematic Viscosity
Not applicable.
Properties Status
---
14

Transport Information

UN numbers, shipping names, transport classes, and regulatory requirements

UN Number
UN2811
Shipping Name
Toxic solids, organic, n.o.s. (Ketoconazole)
Transport Class
6.1 Toxic substances
Packing Group
III
IMDG

F-A, S-A

IATA

F-A, S-A

?

Frequently Asked Questions

Common questions about safety, handling, and properties

What is the hazard signal word for Ketoconazole?

The signal word is danger.

What is Ketoconazole used for?

SU24 Scientific research and development

What are the hazard statements for Ketoconazole?

This substance has 3 hazard statements:

  • H301: Toxic if swallowed.
  • H360: May damage fertility or the unborn child.
  • H373: May cause damage to the kidneys, the liver, the reproductive system and the endocrine system through prolonged or repeated exposure.

What is the melting point of Ketoconazole?

The melting point is Not determined and the boiling point is Not determined.

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