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Safety Data Sheet EN

Itraconazole

CAS 84625-61-6

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01

Identification

Product identifiers, regulatory numbers, and supplier information

Product Information

Product Name
Itraconazole
Product Code
I6657

Regulatory Identifiers

CAS Number
84625-61-6 Check regulations →
REACH No.
A registration number is not available for this substance as the substance or its uses are exempted from registration, the annual tonnage does not require a registration or the registration is envisaged for a later registration deadline.

Identified Uses

Laboratory chemicals, Manufacture of substances

Manufacturers & Suppliers

S

Sigma

manufacturer

S

Sigma-Aldrich BVBA/SPRL

manufacturer

Pegasuslaan 5, B-1831 DIEGEM

+32 3 899 1301

Emergency Contacts

Emergency Contact

070 245245

02

Hazard Identification

GHS classification, signal word, pictograms, and hazard statements

Classified warning

Hazard Classifications

Acute Tox. Cat. 4 H302
Skin Irrit. Cat. 2 H315
Eye Irrit. Cat. 2 H319
STOT SE Cat. 3 H335

GHS Pictograms

GHS07 - Health hazard

GHS07

Hazard Statements

H302 Harmful if swallowed.
H315 Causes skin irritation.
H319 Causes serious eye irritation.
H335 May cause respiratory irritation.

Precautionary Statements

P261 Avoid breathing dust.
P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

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03

Composition / Information on Ingredients

Chemical components, concentration ranges, and hazardous substance identification

Type substance
Chemical Name CAS Number Concentration Hazardous
Itraconazole 84625-61-6 100% Yes
04

First Aid Measures

Emergency procedures for chemical exposure incidents

Inhalation

If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.

Skin contact

Wash off with soap and plenty of water. Consult a physician.

Eye contact

Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.

Ingestion

Rinse mouth with water. Consult a physician.

05

Firefighting Measures

Extinguishing media, specific hazards, and firefighter protection

Suitable media

Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.

Specific hazards

No data available

Firefighter Protection

Wear self-contained breathing apparatus for firefighting if necessary.

06

Accidental Release Measures

Spill cleanup procedures, containment, and environmental protection

Emergency procedures

Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust.

Environmental

Do not let product enter drains.

Cleanup methods

Pick up and arrange disposal without creating dust. Sweep up and shovel.

Materials: suitable, closed containers

Related Products

Similar products with comparable safety profiles

07

Handling and Storage

Safe handling precautions, storage conditions, and workplace requirements

Handling

Avoid contact with skin and eyes. Avoid formation of dust and aerosols.

Storage

Store in cool place. Keep container tightly closed in a dry and well-ventilated place.

08

Exposure Controls / PPE

Occupational exposure limits, engineering controls, and protective equipment

Hands

Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it. Full contact Material: Nitrile rubber Minimum layer thickness: 0,11 mm Break through time: 480 min Material tested:Dermatril® (KCL 740 / Aldrich Z677272, Size M) Splash contact Material: Nitrile rubber Minimum layer thickness: 0,11 mm Break through time: 480 min Material tested:Dermatril® (KCL 740 / Aldrich Z677272, Size M) data source: KCL GmbH, D-36124 Eichenzell, phone +49 (0)6659 87300, e-mail sales@kcl.de, test method: EN374 If used in solution, or mixed with other substances, and under conditions which differ from EN 374, contact the supplier of the CE approved gloves. This recommendation is advisory only and must be evaluated by an industrial hygienist and safety officer familiar with the specific situation of anticipated use by our customers. It should not be construed as offering an approval for any specific use scenario.

Eyes

Safety glasses with side-shields conforming to EN166 Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Respiratory

For nuisance exposures use type P95 (US) or type P1 (EU EN 143) particle respirator.For higher level protection use type OV/AG/P99 (US) or type ABEK-P2 (EU EN 143) respirator cartridges. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).

Skin/Body

Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.

Environmental

Do not let product enter drains.

09

Physical and Chemical Properties

Appearance, physical state, melting point, boiling point, and material characteristics

Density
---
Upper Explosive Limit
---
Evaporation Rate
---
Relative Evaporation Rate
---
Cloud Point
---
Voc Content
---
Softening Point
---
Colour
---
Relative Density
---
Solidification Point
---
Decomposition Temperature
---
Colour Intensity
---
Form
solid
Solubility In Water
---
Vapor Pressure
---
Boiling Point
---
Lower Explosive Limit
---
Solubility
---
Crystallisation Point
---
Solubility In Fat
---
Physical State
solid
Vapor Density
---
Ph
---
Bulk Density
---
Explosive Limits
---
State Under Standard Conditions
---
Flammability
---
Odor
---
Properties Status
---
Metal Corrosion
---
Odor Threshold
---
Molecular Weight
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Dynamic Viscosity
---
Freezing Point
---
Partition Coefficient
---
Appearance
Form: solid
Auto Ignition Temperature
---
Kinematic Viscosity
---
Physical State Data
solid
Flash Point
---
Melting Point
---
10

Stability and Reactivity

Chemical stability, hazardous reactions, and incompatible materials

Stability

Stable under recommended storage conditions.

Reactivity

No data available

Hazardous reactions

No data available

Avoid

No data available

Incompatible

Strong oxidizing agents

Decomposition

Hazardous decomposition products formed under fire conditions. - Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas. Other decomposition products - No data available

12

Ecological Information

Environmental toxicity, biodegradation, and bioaccumulation data

The data for this section has not been processed yet.

13

Disposal Considerations

Waste treatment methods, disposal recommendations, and waste codes

The data for this section has not been processed yet.

14

Transport Information

UN numbers, shipping names, transport classes, and regulatory requirements

15

Regulatory Information

Chemical regulations, safety assessments, and compliance status

The data for this section has not been processed yet.

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Frequently Asked Questions

Common questions about safety, handling, and properties

What is the hazard signal word for Itraconazole?

The signal word is warning.

What is the physical form of Itraconazole?

Itraconazole is a solid appearing as form: solid .

What is Itraconazole used for?

Laboratory chemicals, Manufacture of substances

What are the hazard statements for Itraconazole?

This substance has 4 hazard statements:

  • H302: Harmful if swallowed.
  • H315: Causes skin irritation.
  • H319: Causes serious eye irritation.
  • H335: May cause respiratory irritation.