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Safety Data Sheet EN

Ibrutinib

CAS 936563-96-1
EC 805-642-2

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01

Identification

Product identifiers, regulatory numbers, and supplier information

Product Information

Product Name
Ibrutinib
Product Code
HY-10997
Chemical Name
1-[(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]prop-2-en-1-one
Synonyms
PCI-32765

Regulatory Identifiers

CAS Number
936563-96-1 Check regulations →
EC Number
805-642-2 Check regulations →

Identified Uses

Laboratory chemicals, manufacture of substances.

Manufacturers & Suppliers

M

MedChemExpress USA

Emergency Contacts

Emergency Contact

609-228-6898

02

Hazard Identification

GHS classification, signal word, pictograms, and hazard statements

Classified warning

Hazard Classifications

Acute Tox. Cat. 4 H302
Skin Irrit. Cat. 2 H315
Eye Irrit. Cat. 2A H319
STOT SE Cat. 3 H335

GHS Pictograms

GHS07 - Health hazard

GHS07

Hazard Statements

H302 Harmful if swallowed
H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation

Precautionary Statements

P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302 + P352 IF ON SKIN: Wash with plenty of soap and water.
P304 + P340 IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P330 Rinse mouth.
P362 + P364 Take off contaminated clothing and wash it before reuse.
P403 + P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to in accordance with local regulation.

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03

Composition / Information on Ingredients

Chemical components, concentration ranges, and hazardous substance identification

Type substance
Chemical Name CAS Number Concentration Hazardous
1-[(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]prop-2-en-1-one EC: 805-642-2 936563-96-1 --- No
04

First Aid Measures

Emergency procedures for chemical exposure incidents

Inhalation

Immediately relocate self or casualty to fresh air. If breathing is difficult, give cardiopulmonary resuscitation (CPR). Avoid mouth to-mouth resuscitation.

Skin contact

Rinse skin thoroughly with large amounts of water. Remove contaminated clothing and shoes and call a physician.

Eye contact

Remove any contact lenses, locate eye-wash station, and flush eyes immediately with large amounts of water. Separate eyelids with fingers to ensure adequate flushing. Promptly call a physician.

Ingestion

Wash out mouth with water; Do NOT induce vomiting; call a physician.

Immediate Medical Attention

Treat symptomatically.

Medical Treatment

Treat symptomatically.

05

Firefighting Measures

Extinguishing media, specific hazards, and firefighter protection

The data for this section has not been processed yet.

06

Accidental Release Measures

Spill cleanup procedures, containment, and environmental protection

The data for this section has not been processed yet.

Related Products

Similar products with comparable safety profiles

07

Handling and Storage

Safe handling precautions, storage conditions, and workplace requirements

The data for this section has not been processed yet.

08

Exposure Controls / PPE

Occupational exposure limits, engineering controls, and protective equipment

Engineering

Ensure adequate ventilation. Provide accessible safety shower and eye wash station.

Hands

Protective gloves.

Eyes

Safety goggles with side-shields.

Respiratory

Suitable respirator.

Skin/Body

Impervious clothing.

Environmental

Keep the product away from drains, water courses or the soil. Clean spillages in a safe way as soon as possible.

09

Physical and Chemical Properties

Appearance, physical state, melting point, boiling point, and material characteristics

Form
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Bulk Density
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Crystallisation Point
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Solubility In Fat
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Voc Content
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Vapor Pressure
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Solubility In Water
---
State Under Standard Conditions
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Colour Intensity
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Relative Evaporation Rate
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Cloud Point
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Molecular Weight
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Odor
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Lower Explosive Limit
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Appearance
Solid
Relative Density
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Ph
---
Dynamic Viscosity
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Density
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Metal Corrosion
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Solidification Point
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Properties Status
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Kinematic Viscosity
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Freezing Point
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Colour
---
Decomposition Temperature
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Melting Point
153-158C
Flash Point
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Flammability
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Auto Ignition Temperature
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Partition Coefficient
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Explosive Limits
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Upper Explosive Limit
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Physical State Data
solid
Vapor Density
---
Odor Threshold
---
Boiling Point
715.060.0C at 760 mmHg
Physical State
Solid
Softening Point
---
Solubility
---
Evaporation Rate
---
10

Stability and Reactivity

Chemical stability, hazardous reactions, and incompatible materials

The data for this section has not been processed yet.

12

Ecological Information

Environmental toxicity, biodegradation, and bioaccumulation data

The data for this section has not been processed yet.

13

Disposal Considerations

Waste treatment methods, disposal recommendations, and waste codes

The data for this section has not been processed yet.

14

Transport Information

UN numbers, shipping names, transport classes, and regulatory requirements

15

Regulatory Information

Chemical regulations, safety assessments, and compliance status

The data for this section has not been processed yet.

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Frequently Asked Questions

Common questions about safety, handling, and properties

What other names is Ibrutinib known by?

Ibrutinib is also known as: PCI-32765

What is the hazard signal word for Ibrutinib?

The signal word is warning.

What is the physical form of Ibrutinib?

Ibrutinib is a solid appearing as solid .

What is Ibrutinib used for?

Laboratory chemicals, manufacture of substances.

What are the hazard statements for Ibrutinib?

This substance has 4 hazard statements:

  • H302: Harmful if swallowed
  • H315: Causes skin irritation
  • H319: Causes serious eye irritation
  • H335: May cause respiratory irritation

What is the melting point of Ibrutinib?

The melting point is 153-158C and the boiling point is 715.060.0C at 760 mmHg.

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