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Safety Data Sheet EN

Acalabrutinib

CAS 1420477-60-6

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01

Identification

Product identifiers, regulatory numbers, and supplier information

Product Information

Product Name
Acalabrutinib
Product Code
HY-17600

Regulatory Identifiers

CAS Number
1420477-60-6 Check regulations →

Identified Uses

Laboratory chemicals, manufacture of substances.

Manufacturers & Suppliers

M

MedChemExpress USA

manufacturer

609-228-6898

Emergency Contacts

Emergency Contact

609-228-6898

02

Hazard Identification

GHS classification, signal word, pictograms, and hazard statements

Classified warning

Hazard Classifications

Acute Tox. Cat. 4 H302
Skin Irrit. Cat. 2 H315
Eye Irrit. Cat. 2A H319
STOT SE Cat. 3 H335

GHS Pictograms

GHS07 - Health hazard

GHS07

Hazard Statements

H302 Harmful if swallowed
H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation

Precautionary Statements

P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302 + P352 IF ON SKIN: Wash with plenty of soap and water.
P304 + P340 IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P330 Rinse mouth.
P362 + P364 Take off contaminated clothing and wash it before reuse.
P403 + P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to in accordance with local regulation.

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03

Composition / Information on Ingredients

Chemical components, concentration ranges, and hazardous substance identification

Type substance

Synonyms: ACP-196

Chemical Name CAS Number Concentration Hazardous
ACP-196 1420477-60-6 --- No
04

First Aid Measures

Emergency procedures for chemical exposure incidents

Inhalation

Immediately relocate self or casualty to fresh air. If breathing is difficult, give cardiopulmonary resuscitation (CPR). Avoid mouth-to-mouth resuscitation.

Skin contact

Rinse skin thoroughly with large amounts of water. Remove contaminated clothing and shoes and call a physician.

Eye contact

Remove any contact lenses, locate eye-wash station, and flush eyes immediately with large amounts of water. Separate eyelids with fingers to ensure adequate flushing. Promptly call a physician.

Ingestion

Wash out mouth with water; Do NOT induce vomiting; call a physician.

Medical Treatment

Treat symptomatically.

05

Firefighting Measures

Extinguishing media, specific hazards, and firefighter protection

Suitable media

Use water spray, dry chemical, foam, and carbon dioxide fire extinguisher.

Specific hazards

During combustion, may emit irritant fumes.

Firefighter Protection

Wear self-contained breathing apparatus and protective clothing.

06

Accidental Release Measures

Spill cleanup procedures, containment, and environmental protection

Emergency procedures

Evacuate personnel to safe areas.

Environmental

Try to prevent further leakage or spillage. Keep the product away from drains or water courses.

Cleanup methods

Decontaminate surfaces and equipment by scrubbing with alcohol

Materials: alcohol

—

Related Products

Similar products with comparable safety profiles

07

Handling and Storage

Safe handling precautions, storage conditions, and workplace requirements

Handling

Avoid inhalation, contact with eyes and skin. Avoid dust and aerosol formation. Use only in areas with appropriate exhaust ventilation.

Storage

Keep container tightly sealed in cool, well-ventilated area. Keep away from direct sunlight and sources of ignition.

Fire prevention

Keep away from sources of ignition.

08

Exposure Controls / PPE

Occupational exposure limits, engineering controls, and protective equipment

Engineering

Ensure adequate ventilation. Provide accessible safety shower and eye wash station.

Hands

Protective gloves.

Eyes

Safety goggles with side-shields.

Respiratory

Suitable respirator.

Skin/Body

Impervious clothing.

Environmental

Keep the product away from drains, water courses or the soil. Clean spillages in a safe way as soon as possible.

09

Physical and Chemical Properties

Appearance, physical state, melting point, boiling point, and material characteristics

Solidification Point
---
Upper Explosive Limit
No data available
Kinematic Viscosity
---
Ph
No data available
Physical State Data
solid
Solubility In Fat
---
Colour
---
Relative Evaporation Rate
---
Flammability
No data available
Boiling Point
No data available
Metal Corrosion
---
Odor Threshold
No data available
Freezing Point
215°C
Bulk Density
---
Physical State
Solid
Odor
No data available
Cloud Point
---
Auto Ignition Temperature
No data available
Appearance
Solid
Molecular Weight
---
Colour Intensity
---
Dynamic Viscosity
---
Relative Density
1.37g/cm³
Voc Content
---
Explosive Limits
---
Decomposition Temperature
No data available
Form
---
Density
---
State Under Standard Conditions
---
Properties Status
---
Partition Coefficient
No data available
Flash Point
No data available
Solubility
---
Vapor Density
No data available
Evaporation Rate
No data available
Solubility In Water
No data available
Crystallisation Point
---
Melting Point
215°C
Vapor Pressure
No data available
Lower Explosive Limit
No data available
Softening Point
---
10

Stability and Reactivity

Chemical stability, hazardous reactions, and incompatible materials

Stability

Stable under recommended storage conditions.

Reactivity

No data available.

Hazardous reactions

No data available.

Avoid

No data available.

Incompatible

Strong acids/alkalis, strong oxidising/reducing agents.

Decomposition

Under fire conditions, may decompose and emit toxic fumes. Other decomposition products - no data available.

12

Ecological Information

Environmental toxicity, biodegradation, and bioaccumulation data

The data for this section has not been processed yet.

13

Disposal Considerations

Waste treatment methods, disposal recommendations, and waste codes

Disposal

Dispose substance in accordance with prevailing country, federal, state and local regulations.

14

Transport Information

UN numbers, shipping names, transport classes, and regulatory requirements

15

Regulatory Information

Chemical regulations, safety assessments, and compliance status

?

Frequently Asked Questions

Common questions about safety, handling, and properties

What is the hazard signal word for Acalabrutinib?

The signal word is warning.

What is the physical form of Acalabrutinib?

Acalabrutinib is a solid appearing as solid . It has no data available odor.

What is Acalabrutinib used for?

Laboratory chemicals, manufacture of substances.

What are the hazard statements for Acalabrutinib?

This substance has 4 hazard statements:

  • H302: Harmful if swallowed
  • H315: Causes skin irritation
  • H319: Causes serious eye irritation
  • H335: May cause respiratory irritation

What is the melting point of Acalabrutinib?

The melting point is 215°C and the boiling point is No data available.