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Safety Data Sheet EN

Abemaciclib

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01

Identification

Product identifiers, regulatory numbers, and supplier information

Product Information

Product Name
Abemaciclib
Product Code
TRC-A115153-10MG

Regulatory Identifiers

CAS Number
N/A

Identified Uses

Laboratory use

Uses advised against

No information available

Manufacturers & Suppliers

T

Toronto Research Chemicals

national supplier

2 Brisbane Road Toronto, ON M3J 2J8

Emergency Contacts

Toronto Research Chemicals

+1(416) 665-9696

between 0800-1700 (GMT-5)

CHEMTREC

1-800-424-9300

CHEMTREC

+1 703-741-5970

02

Hazard Identification

GHS classification, signal word, pictograms, and hazard statements

Classified danger

Hazard Classifications

Repr. Cat. 1B
STOT RE Cat. 2
Aquatic Acute Cat. 1
Aquatic Chronic Cat. 1

GHS Pictograms

GHS08 - Serious health hazard

GHS08

GHS09 - Environmental hazard

GHS09

Hazard Statements

H410 Very toxic to aquatic life with long lasting effects
May damage fertility or the unborn child
May cause damage to organs through prolonged or repeated exposure

Precautionary Statements

Obtain special instructions before use
Do not handle until all safety precautions have been read and understood
Wear protective gloves, protective clothing, eye protection and face protection
Do not breathe dust, fume, gas, mist, vapors and spray
Avoid release to the environment
IF exposed or concerned: Get medical advice/attention
Collect spillage
Store locked up
Dispose of contents and container to an approved waste disposal plant

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03

Composition / Information on Ingredients

Chemical components, concentration ranges, and hazardous substance identification

Type Substance
Chemical Name CAS Number Concentration Hazardous
N-(5-((4-ethylpiperazin-1-yl)methyl)pyridin-2-yl)-5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)pyrimidin-2-amine EC: 806-670-8 1231929-97-7 90 - 100% No
04

First Aid Measures

Emergency procedures for chemical exposure incidents

Inhalation

Remove to fresh air.

Skin contact

Wash skin with soap and water.

Eye contact

Rinse thoroughly with plenty of water for at least 15 minutes, lifting lower and upper eyelids. Consult a doctor.

Ingestion

Rinse mouth.

Medical Treatment

Treat symptomatically.

05

Firefighting Measures

Extinguishing media, specific hazards, and firefighter protection

The data for this section has not been processed yet.

06

Accidental Release Measures

Spill cleanup procedures, containment, and environmental protection

The data for this section has not been processed yet.

Related Products

Similar products with comparable safety profiles

07

Handling and Storage

Safe handling precautions, storage conditions, and workplace requirements

The data for this section has not been processed yet.

08

Exposure Controls / PPE

Occupational exposure limits, engineering controls, and protective equipment

Engineering

Showers Eyewash stations Ventilation systems.

Hands

The protective gloves to be used must comply with the specifications of EC Directive 89/686/EEC and the related standard EN374. Wear suitable gloves. Wear protective Viton ⁿ™ gloves.

Eyes

Avoid contact with eyes. Wear safety glasses with side shields (or goggles).

Respiratory

No protective equipment is needed under normal use conditions. If exposure limits are exceeded or irritation is experienced, ventilation and evacuation may be required.

Skin/Body

Wear suitable protective clothing.

Environmental

Do not allow into any sewer, on the ground or into any body of water.

09

Physical and Chemical Properties

Appearance, physical state, melting point, boiling point, and material characteristics

Solubility In Water
Slightly soluble
Auto Ignition Temperature
No data available
Melting Point
175 - 178 C / 347 - 352.4 F
Dynamic Viscosity
No data available
Lower Explosive Limit
No data available
Solubility
No data available
Physical State Data
---
Appearance
No information available
Partition Coefficient
No data available
Relative Density
No data available
Freezing Point
175 - 178 C / 347 - 352.4 F
Density
No information available
Boiling Point
No data available
Solidification Point
---
Colour Intensity
---
Explosive Limits
---
Flammability
No data available
Ph
No data available
Solubility In Fat
---
Properties Status
---
Colour
No information available
State Under Standard Conditions
---
Form
---
Bulk Density
No information available
Voc Content
No information available
Vapor Pressure
No data available
Molecular Weight
506.59
Softening Point
No information available
Odor Threshold
No information available
Evaporation Rate
No data available
Upper Explosive Limit
No data available
Odor
No information available
Crystallisation Point
---
Cloud Point
---
Metal Corrosion
---
Relative Evaporation Rate
---
Kinematic Viscosity
No data available
Flash Point
No data available
Decomposition Temperature
---
Vapor Density
---
Physical State
No information available
10

Stability and Reactivity

Chemical stability, hazardous reactions, and incompatible materials

The data for this section has not been processed yet.

12

Ecological Information

Environmental toxicity, biodegradation, and bioaccumulation data

The data for this section has not been processed yet.

13

Disposal Considerations

Waste treatment methods, disposal recommendations, and waste codes

The data for this section has not been processed yet.

14

Transport Information

UN numbers, shipping names, transport classes, and regulatory requirements

UN Number
UN3077
Shipping Name
Environmentally hazardous substances, solid, n.o.s. (Abemaciclib)
Transport Class
9
Packing Group
III
15

Regulatory Information

Chemical regulations, safety assessments, and compliance status

The data for this section has not been processed yet.

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Frequently Asked Questions

Common questions about safety, handling, and properties

What is the hazard signal word for Abemaciclib?

The signal word is danger.

What is the physical form of Abemaciclib?

Abemaciclib is a no information available appearing as no information available with no information available color. It has no information available odor.

What is the solubility of Abemaciclib?

No data available

What is Abemaciclib used for?

Laboratory use

What are the hazard statements for Abemaciclib?

This substance has 3 hazard statements:

  • H410: Very toxic to aquatic life with long lasting effects
  • May damage fertility or the unborn child
  • May cause damage to organs through prolonged or repeated exposure

What is the melting point of Abemaciclib?

The melting point is 175 - 178 C / 347 - 352.4 F and the boiling point is No data available.

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