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Safety Data Sheet EN

HybReady

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01

Identification

Product identifiers, regulatory numbers, and supplier information

Product Information

Product Name
HybReady
Product Code
05917557001

Regulatory Identifiers

CAS Number
N/A

Identified Uses

Laboratory chemicals, Refer to product literature for further details.

Manufacturers & Suppliers

R

Roche Diagnostics Limited

manufacturer

Charles Avenue, Burgess Hill, RH15 9RY West Sussex, United Kingdom

+44 1444 256000

Emergency Contacts

Product Safety / Vigilance (Roche Diagnostics Ltd.)

+44 (0)808 100 1920

Product Safety / Vigilance (Roche Diagnostics Ltd.)

1800 409 564

NPIS

+44 344 892 0111

NHS Direct in Wales

111

NHS Direct in Wales

+44 845 4647

NHS 111 in England/NHS 24 in Scotland

111

02

Hazard Identification

GHS classification, signal word, pictograms, and hazard statements

Classified danger

Hazard Classifications

Carc. Cat. 2 H351
Repr. Cat. 1B H360D

GHS Pictograms

GHS08 - Serious health hazard

GHS08

Hazard Statements

H351 Suspected of causing cancer.
H360D May damage the unborn child.

Precautionary Statements

P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P280 Wear protective gloves/ protective clothing/ eye protection/ face protection/ hearing protection.
P308 + P313 IF exposed or concerned: Get medical advice/ attention.
P405 Store locked up.
P501 Dispose of contents/ container to an approved waste disposal plant.

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03

Composition / Information on Ingredients

Chemical components, concentration ranges, and hazardous substance identification

Type mixture
Chemical Name CAS Number Concentration Hazardous
Formamide EC: 200-842-0 75-12-7 30 - 50% Yes
Disodium dihydrogen ethylenediaminetetraacetate EC: 205-358-3 139-33-3 0.1% Yes
04

First Aid Measures

Emergency procedures for chemical exposure incidents

Inhalation

Move to fresh air. If unconscious, place in recovery position and seek medical advice. If symptoms persist, call a physician.

Skin contact

If on skin, rinse well with water.

Eye contact

Flush eyes with water as a precaution. Remove contact lenses. Protect unharmed eye. Keep eye wide open while rinsing. If eye irritation persists, consult a specialist.

Ingestion

Keep respiratory tract clear. Do not give milk or alcoholic beverages. Never give anything by mouth to an unconscious person. If symptoms persist, call a physician. Take victim immediately to hospital.

Immediate Medical Attention

Take victim immediately to hospital.

Medical Treatment

The first aid procedure should be established in consultation with the doctor responsible for industrial medicine.

05

Firefighting Measures

Extinguishing media, specific hazards, and firefighter protection

Suitable media

Use extinguishing measures that are appropriate to local circumstances and the surrounding environment.

Unsuitable media

High volume water jet

Specific hazards

Do not allow run-off from fire fighting to enter drains or water courses.

Firefighter Protection

Wear self-contained breathing apparatus for firefighting if necessary.

06

Accidental Release Measures

Spill cleanup procedures, containment, and environmental protection

Emergency procedures

Use personal protective equipment. Refer to protective measures listed in sections 7 and 8.

Environmental

Prevent product from entering drains. Prevent further leakage or spillage if safe to do so.

Cleanup methods

Soak up with inert absorbent material (e.g. sand, silica gel, acid binder, universal binder, sawdust).

Materials: inert absorbent material (e.g. sand, silica gel, acid binder, universal binder, sawdust)

—

Related Products

Similar products with comparable safety profiles

07

Handling and Storage

Safe handling precautions, storage conditions, and workplace requirements

Handling

Do not breathe vapours/dust. Avoid exposure - obtain special instructions before use. Avoid contact with skin and eyes. For personal protection see section 8. Smoking, eating and drinking should be prohibited in the application area. Dispose of rinse water in accordance with local and national regulations.

Storage

Keep container tightly closed in a dry and well-ventilated place. Observe label precautions.

Hygiene

When using do not eat or drink. When using do not smoke. Wash hands before breaks and at the end of workday.

Fire prevention

Normal measures for preventive fire protection.

08

Exposure Controls / PPE

Occupational exposure limits, engineering controls, and protective equipment

Engineering

No data available

Hands

In case of contact through splashing: Material: Nitrile rubber, Break through time: > 240 min, Glove thickness: 0,11 mm. In case of full contact: Material: Latex gloves, Break through time: > 480 min, Glove thickness: 0,6 mm. Remarks: The selected protective gloves have to satisfy the specifications of Regulation (EU) 2016/425 and the standard EN 374 derived from it.

Eyes

Eye wash bottle with pure water, Tightly fitting safety goggles

Respiratory

In the case of vapour formation use a respirator with an approved filter.

Skin/Body

Impervious clothing. Choose body protection according to the amount and concentration of the dangerous substance at the work place.

09

Physical and Chemical Properties

Appearance, physical state, melting point, boiling point, and material characteristics

Language Code
---
Physical State
liquid
Physical State Data
liquid
State Under Standard Conditions
---
Appearance
liquid
Colour
colourless
Colour Intensity
---
Form
---
Odor
amine-like
Odor Threshold
No data available
Ph
7,3 - 7,5
Melting Point
No data available
Boiling Point
No data available
Flash Point
does not flash
Freezing Point
---
Softening Point
---
Solidification Point
---
Cloud Point
---
Crystallisation Point
---
Relative Evaporation Rate
---
Evaporation Rate
No data available
Vapor Pressure
No data available
Vapor Density
---
Relative Density
No data available
Bulk Density
---
Density
1,190 g/cm3
Flammability
Does not sustain combustion.
Upper Explosive Limit
No data available
Lower Explosive Limit
No data available
Explosive Limits
---
Auto Ignition Temperature
No data available
Decomposition Temperature
No data available
Solubility
completely miscible
Partition Coefficient
No data available
Solubility In Water
completely miscible
Solubility In Fat
---
Molecular Weight
---
Voc Content
---
Metal Corrosion
---
Dynamic Viscosity
No data available
Kinematic Viscosity
No data available
Properties Status
---
10

Stability and Reactivity

Chemical stability, hazardous reactions, and incompatible materials

Stability

Stable under normal conditions.

Reactivity

No dangerous reaction known under conditions of normal use.

Hazardous reactions

No decomposition if stored and applied as directed.

Avoid

Heat

Incompatible

Strong acids and strong bases

Decomposition

No decomposition if stored and applied as directed.

12

Ecological Information

Environmental toxicity, biodegradation, and bioaccumulation data

12.1 Toxicity

### Product: #### Ecotoxicology Assessment Toxicity Data on Soil : Not expected to adsorb on soil. Other organisms relevant to the environment : No data available ### Components: #### Formamide: Toxicity to fish : LC50 (Leuciscus idus (Golden orfe)): 6.569 mg/l Exposure time: 96 h Test Type: static test Method: DIN 38412 Toxicity to daphnia and other aquatic invertebrates : EC50 (Daphnia magna (Water flea)): > 500 mg/l Exposure time: 48 h Test Type: static test Method: Regulation (EC) No. 440/2008, Annex, C.2 Toxicity to algae/aquatic plants : ErC50 (Desmodesmus subspicatus (green algae)): > 500 mg/l Exposure time: 96 h Test Type: static test Method: DIN 38412 Toxicity to microorganisms : EC50 (activated sludge): > 1.000 mg/l Exposure time: 30 min Test Type: static test Method: OECD Test Guideline 209 #### Ecotoxicology Assessment Toxicity Data on Soil : Not expected to adsorb on soil. Other organisms relevant to the environment : No data available ## Disodium dihydrogen ethylenediaminetetraacetate: Toxicity to fish: LC50 (Lepomis macrochirus (Bluegill sunfish)): > 100 mg/l Exposure time: 96 h Test Type: static test Remarks: nominal concentration Based on data from similar materials Toxicity to daphnia and other aquatic invertebrates: EC50 (Daphnia magna (Water flea)): > 100 mg/l Exposure time: 48 h Test Type: static test Method: DIN 38412 Remarks: nominal concentration Toxicity to algae/aquatic plants: ErC50 (Pseudokirchneriella subcapitata (green algae)): > 100 mg/l Exposure time: 72 h Test Type: static test Remarks: Based on data from similar materials Toxicity to microorganisms: EC20 (activated sludge): > 500 mg/l Exposure time: 30 min Method: OECD Test Guideline 209 Toxicity to fish (Chronic toxicity): NOEC: >= 36,9 mg/l Exposure time: 35 d Species: Danio rerio (zebra fish) Test Type: flow-through test Method: OECD Test Guideline 210 Remarks: Based on data from similar materials

12.2 Persistence and degradability

Components: Formamide: Biodegradability: Test Type: aerobic Result: Readily biodegradable. Biodegradation: 99 % Exposure time: 28 d Method: OECD Test Guideline 301A Photodegradation: Rate constant: 2E-12 cm3/s Degradation (indirect photolysis): 50 % Disodium dihydrogen ethylenediaminetetraacetate: Biodegradability: Test Type: aerobic Result: Not readily biodegradable. Method: OECD Test Guideline 301D Remarks: Based on data from similar materials

12.3 Bioaccumulative potential

### Components: **Formamide:** **Bioaccumulation**: Remarks: Due to the distribution coefficient n-octanol/water, accumulation in organisms is not expected. **Partition coefficient:** n-octanol/water : log Pow: -0,82 (25 °C) ### Disodium dihydrogen ethylenediaminetetraacetate: **Bioaccumulation**: Species: Lepomis macrochirus (Bluegill sunfish) Exposure time: 28 d Bioconcentration factor (BCF): 1,8 Remarks: Bioaccumulation is unlikely. **Partition coefficient:** n-octanol/water : log Pow: -4,3 (25 °C) pH: 4,5

12.4 Mobility in soil

No data available

12.5 Results of PBT and vPvB assessment

### Product: **Assessment**: This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.

The substance/mixture contains no components considered to be PBT or vPvB at levels of 0.1% or higher.

12.6 Other adverse effects

Product: Endocrine disrupting potential: The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher.

The substance/mixture does not contain components considered to have endocrine disrupting properties at levels of 0.1% or higher.

13

Disposal Considerations

Waste treatment methods, disposal recommendations, and waste codes

Treatment

Do not contaminate ponds, waterways or ditches with chemical or used container. Send to a licensed waste management company. Can be disposed as waste water, when in compliance with local regulations.

Disposal

Send to a licensed waste management company.

14

Transport Information

UN numbers, shipping names, transport classes, and regulatory requirements

15

Regulatory Information

Chemical regulations, safety assessments, and compliance status

Chemical Safety Assessment Performed

Take note of The Management of Health and Safety at Work Regulations 1999 (requirements relating to new and expectant mothers at work contained in Regulation 16 to 18) and of the Pregnant Workers Directive 92/85/EEC. Take note of The Management of Health and Safety at Work Regulations 1999 (requirements relating to protection of young people at work contained in Regulation 19) and of Directive 94/33/EC on the protection of young people at work.

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Frequently Asked Questions

Common questions about safety, handling, and properties

What is the hazard signal word for HybReady?

The signal word is danger.

What is the physical form of HybReady?

HybReady is a liquid appearing as liquid with colourless color. It has amine-like odor.

What is the solubility of HybReady?

completely miscible

What is HybReady used for?

Laboratory chemicals, Refer to product literature for further details.

What are the hazard statements for HybReady?

This substance has 2 hazard statements:

  • H351: Suspected of causing cancer.
  • H360D: May damage the unborn child.

What is the melting point of HybReady?

The melting point is No data available and the boiling point is No data available.