Identification
Product identifiers, regulatory numbers, and supplier information
Product Information
- Product Name
- Trizma® base
- Product Code
- T1503
Regulatory Identifiers
- CAS Number
- 77-86-1 Check regulations →
- REACH No.
- 01-2119957659-16-XXXX
Identified Uses
Laboratory chemicals, Manufacture of substances
Manufacturers & Suppliers
Merck Life Science BV/SRL
manufacturer
Brusselsesteenweg 288 B-3090 OVERIJSE
+32 (0)3 899-1301
Emergency Contacts
CHEMTREC
+(32) 28 083237
Anti-poison centre
070 245245
Hazard Identification
GHS classification, signal word, pictograms, and hazard statements
Hazard Classifications
GHS Pictograms
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Composition / Information on Ingredients
Chemical components, concentration ranges, and hazardous substance identification
Synonyms : 2-Amino-2-(hydroxymethyl)-1,3-propanediol THAM Trometamol Tris base Tris(hydroxymethyl)aminomethane Formula : C4H11NO3 Molecular weight : 121,14 g/mol CAS-No. : 77-86-1 EC-No. : 201-064-4
| Chemical Name | CAS Number | Concentration | Hazardous |
|---|---|---|---|
| 2-Amino-2-(hydroxymethyl)-1,3-propanediol EC: 201-064-4 | 77-86-1 | --- | No |
Notes
No components need to be disclosed according to the applicable regulations.
First Aid Measures
Emergency procedures for chemical exposure incidents
After inhalation: fresh air.
In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with water/ shower.
After eye contact: rinse out with plenty of water. Remove contact lenses.
After swallowing: make victim drink water (two glasses at most). Consult doctor if feeling unwell.
Firefighting Measures
Extinguishing media, specific hazards, and firefighter protection
Water Foam Carbon dioxide (CO2) Dry powder
For this substance/mixture no limitations of extinguishing agents are given.
Carbon oxides Nitrogen oxides (NOx) Combustible. Development of hazardous combustion gases or vapours possible in the event of fire.
Suppress (knock down) gases/vapors/mists with a water spray jet.
Firefighter Protection
In the event of fire, wear self-contained breathing apparatus.
Accidental Release Measures
Spill cleanup procedures, containment, and environmental protection
Avoid inhalation of dusts. Evacuate the danger area, observe emergency procedures, consult an expert.
Do not let product enter drains.
Take up dry. Clean up affected area.
Related Products
Similar products with comparable safety profiles
Handling and Storage
Safe handling precautions, storage conditions, and workplace requirements
For precautions see section 2.2.
Tightly closed. Dry.
Exposure Controls / PPE
Occupational exposure limits, engineering controls, and protective equipment
Full contact Material: Nitrile rubber Minimum layer thickness: 0,11 mm Break through time: 480 min Material tested:KCL 741 Dermatril® L. Splash contact Material: Nitrile rubber Minimum layer thickness: 0,11 mm Break through time: 480 min Material tested:KCL 741 Dermatril® L. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN374 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell, Internet: www.kcl.de).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Safety glasses
required when dusts are generated. Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system. Recommended Filter type: Filter type P1. The entrepeneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer. These measures have to be properly documented.
Do not let product enter drains.
Physical and Chemical Properties
Appearance, physical state, melting point, boiling point, and material characteristics
Stability and Reactivity
Chemical stability, hazardous reactions, and incompatible materials
The product is chemically stable under standard ambient conditions (room temperature) .
The following applies in general to flammable organic substances and mixtures: in correspondingly fine distribution, when whirled up a dust explosion potential may generally be assumed.
Violent reactions possible with: Oxidizing agents, Bases. Caution! In contact with nitrites, nitrates, nitrous acid possible liberation of nitrosamines!
no information available
No data available
In the event of fire: see section 5
Ecological Information
Environmental toxicity, biodegradation, and bioaccumulation data
The data for this section has not been processed yet.
Disposal Considerations
Waste treatment methods, disposal recommendations, and waste codes
The data for this section has not been processed yet.
Transport Information
UN numbers, shipping names, transport classes, and regulatory requirements
Regulatory Information
Chemical regulations, safety assessments, and compliance status
The data for this section has not been processed yet.
Frequently Asked Questions
Common questions about safety, handling, and properties
What is the hazard signal word for Trizma® base?
The signal word is no signal word.
What is the physical form of Trizma® base?
Trizma® base is a crystalline with white color. It has slight, characteristic odor.
What is Trizma® base used for?
Laboratory chemicals, Manufacture of substances
What is the melting point of Trizma® base?
The melting point is Melting point/range: 169 °C at ca.1.013 hPa - OECD Test Guideline 102 and the boiling point is 288 °C at 1.013 hPa - OECD Test Guideline 103 - Decomposition at boiling point..