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Safety Data Sheet EN

Trizma® base

CAS 77-86-1

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01

Identification

Product identifiers, regulatory numbers, and supplier information

Product Information

Product Name
Trizma® base
Product Code
T1503

Regulatory Identifiers

CAS Number
77-86-1 Check regulations →
REACH No.
01-2119957659-16-XXXX

Identified Uses

Laboratory chemicals, Manufacture of substances

Manufacturers & Suppliers

S

Sigma

manufacturer

S

Sigma-Aldrich Chemie GmbH

manufacturer

Eschenstrasse 5, D-82024 TAUFKIRCHEN

+49 (0)89 6513-1130

Emergency Contacts

CHEMTREC Deutschland

0800 181 7059

CHEMTREC weltweit

+49 (0)696 43508409

02

Hazard Identification

GHS classification, signal word, pictograms, and hazard statements

Classified no signal word

Hazard Classifications

Not Classified

GHS Pictograms

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03

Composition / Information on Ingredients

Chemical components, concentration ranges, and hazardous substance identification

Type substance
Chemical Name CAS Number Concentration Hazardous
2-Amino-2-(hydroxymethyl)-1,3-propanediol EC: 201-064-4 --- --- No

Notes

Remarks : No hazardous ingredients

04

First Aid Measures

Emergency procedures for chemical exposure incidents

Inhalation

After inhalation: fresh air.

Skin contact

In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with water/ shower.

Eye contact

After eye contact: rinse out with plenty of water. Remove contact lenses.

Ingestion

After swallowing: make victim drink water (two glasses at most). Consult doctor if feeling unwell.

05

Firefighting Measures

Extinguishing media, specific hazards, and firefighter protection

Suitable media

Water, Foam, Carbon dioxide (CO2), Dry powder

Unsuitable media

For this substance/mixture no limitations of extinguishing agents are given.

Specific hazards

Combustible. Development of hazardous combustion gases or vapours possible in the event of fire.

Instructions

Suppress (knock down) gases/vapours/mists with a water spray jet.

Firefighter Protection

In the event of fire, wear self-contained breathing apparatus.

06

Accidental Release Measures

Spill cleanup procedures, containment, and environmental protection

Emergency procedures

Avoid inhalation of dusts. Evacuate the danger area, observe emergency procedures, consult an expert.

Environmental

Do not let product enter drains.

Cleanup methods

Take up dry. Clean up affected area.

Related Products

Similar products with comparable safety profiles

07

Handling and Storage

Safe handling precautions, storage conditions, and workplace requirements

Handling

For precautions see section 2.2.

Storage

Tightly closed. Dry.

Hygiene

Change contaminated clothing. Wash hands after working with substance.

08

Exposure Controls / PPE

Occupational exposure limits, engineering controls, and protective equipment

Hands

Material : Nitrile rubber, Break through time : 480 min, Glove thickness : 0,11 mm, Protective index : Full contact, Manufacturer : KCL 741 Dermatril® L. Material : Nitrile rubber, Break through time : 480 min, Glove thickness : 0,11 mm, Protective index : Splash contact, Manufacturer : KCL 741 Dermatril® L. Remarks : This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN 16523-1 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell, Internet: www.kcl.de).

Eyes

Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Safety glasses

Respiratory

required when dusts are generated. Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system. Recommended Filter : Filter type P1. Type: The entrepreneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer. These measures have to be properly documented.

Environmental

Do not let product enter drains.

09

Physical and Chemical Properties

Appearance, physical state, melting point, boiling point, and material characteristics

Dynamic Viscosity
No data available
Vapor Density
---
Physical State Data
solid
Freezing Point
---
Form
crystalline
Crystallisation Point
---
Solubility In Water
678 g/l (20 °C)
Metal Corrosion
---
Vapor Pressure
< 0,1 hPa (20 °C)
Evaporation Rate
No data available
Physical State
solid
Odor Threshold
---
Auto Ignition Temperature
No data available
Colour
white
Solubility
---
Decomposition Temperature
143 °C
Solidification Point
---
Odor
slight, characteristic
Kinematic Viscosity
Not applicable
Relative Density
1,32 (20,4 °C)
Voc Content
---
Appearance
---
State Under Standard Conditions
---
Upper Explosive Limit
No data available
Cloud Point
---
Solubility In Fat
---
Melting Point
169 °C (ca. 1.013 hPa)
Ph
10,2 - 10,6 (20 °C)
Boiling Point
288 °C (1.013 hPa)
Flash Point
Not applicable
Flammability
No data available
Relative Evaporation Rate
---
Softening Point
---
Density
1,32 g/cm³ (20 °C)
Properties Status
---
Bulk Density
---
Partition Coefficient
log Pow: -2,31 (20 °C)
Lower Explosive Limit
No data available
Explosive Limits
---
Molecular Weight
121,14 g/mol
Colour Intensity
---
10

Stability and Reactivity

Chemical stability, hazardous reactions, and incompatible materials

Stability

The product is chemically stable under standard ambient conditions (room temperature).

Reactivity

The following applies in general to flammable organic substances and mixtures: in correspondingly fine distribution, when whirled up a dust explosion potential may generally be assumed.

Hazardous reactions

Violent reactions possible with: Oxidizing agents, Bases, Caution! In contact with nitrites, nitrates, nitrous acid possible liberation of nitrosamines!

Avoid

no information available

Incompatible

No data available

Decomposition

In the event of fire: see section 5

12

Ecological Information

Environmental toxicity, biodegradation, and bioaccumulation data

The data for this section has not been processed yet.

13

Disposal Considerations

Waste treatment methods, disposal recommendations, and waste codes

The data for this section has not been processed yet.

14

Transport Information

UN numbers, shipping names, transport classes, and regulatory requirements

15

Regulatory Information

Chemical regulations, safety assessments, and compliance status

The data for this section has not been processed yet.

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Frequently Asked Questions

Common questions about safety, handling, and properties

What is the hazard signal word for Trizma® base?

The signal word is no signal word.

What is the physical form of Trizma® base?

Trizma® base is a solid with white color. It has slight, characteristic odor.

What is Trizma® base used for?

Laboratory chemicals, Manufacture of substances

What is the melting point of Trizma® base?

The melting point is 169 °C (ca. 1.013 hPa) and the boiling point is 288 °C (1.013 hPa).