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Safety Data Sheet EN

Trizma® hydrochloride

CAS 1185-53-1

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01

Identification

Product identifiers, regulatory numbers, and supplier information

Product Information

Product Name
Trizma® hydrochloride
Product Code
T3253

Regulatory Identifiers

CAS Number
1185-53-1 Check regulations →
REACH No.
A registration number is not available for this substance as the substance or its uses are exempted from registration, the annual tonnage does not require a registration or the registration is envisaged for a later registration deadline.

Identified Uses

Laboratory chemicals, Manufacture of substances

Manufacturers & Suppliers

S

Sigma

manufacturer

S

Sigma-Aldrich BVBA/SPRL

distributor

Pegasuslaan 5, B-1831 DIEGEM

+32 3 899 1301

Emergency Contacts

Emergency Contact

070 245245

02

Hazard Identification

GHS classification, signal word, pictograms, and hazard statements

Classified no signal word

Hazard Classifications

Not Classified

GHS Pictograms

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03

Composition / Information on Ingredients

Chemical components, concentration ranges, and hazardous substance identification

Type substance
Chemical Name CAS Number Concentration Hazardous
Tris(hydroxymethyl)aminomethane hydrochloride EC: 214-684-5 1185-53-1 --- No

No components need to be disclosed according to the applicable regulations.

04

First Aid Measures

Emergency procedures for chemical exposure incidents

Inhalation

If breathed in, move person into fresh air. If not breathing, give artificial respiration.

Skin contact

Wash off with soap and plenty of water.

Eye contact

Flush eyes with water as a precaution.

Ingestion

Never give anything by mouth to an unconscious person. Rinse mouth with water.

05

Firefighting Measures

Extinguishing media, specific hazards, and firefighter protection

Suitable media

Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.

Specific hazards

No data available

Firefighter Protection

Wear self-contained breathing apparatus for firefighting if necessary.

06

Accidental Release Measures

Spill cleanup procedures, containment, and environmental protection

Emergency procedures

Avoid dust formation. Avoid breathing vapours, mist or gas.

Environmental

No special environmental precautions required.

Cleanup methods

Sweep up and shovel.

Materials: suitable, closed containers

Related Products

Similar products with comparable safety profiles

07

Handling and Storage

Safe handling precautions, storage conditions, and workplace requirements

Handling

For precautions see section 2.2.

Storage

Store in cool place. Keep container tightly closed in a dry and well-ventilated place.

08

Exposure Controls / PPE

Occupational exposure limits, engineering controls, and protective equipment

Engineering

General industrial hygiene practice.

Hands

Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it. Full contact: Material: Nitrile rubber, Minimum layer thickness: 0,11 mm, Break through time: 480 min, Material tested: Dermatril® (KCL 740 / Aldrich Z677272, Size M). Splash contact: Material: Nitrile rubber, Minimum layer thickness: 0,11 mm, Break through time: 480 min, Material tested: Dermatril® (KCL 740 / Aldrich Z677272, Size M). data source: KCL GmbH, D-36124 Eichenzell, phone +49 (0)6659 87300, e-mail sales@kcl.de, test method: EN374. If used in solution, or mixed with other substances, and under conditions which differ from EN 374, contact the supplier of the CE approved gloves. This recommendation is advisory only and must be evaluated by an industrial hygienist and safety officer familiar with the specific situation of anticipated use by our customers. It should not be construed as offering an approval for any specific use scenario.

Eyes

Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Respiratory

Respiratory protection is not required. Where protection from nuisance levels of dusts are desired, use type N95 (US) or type P1 (EN 143) dust masks. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).

Skin/Body

Choose body protection in relation to its type, to the concentration and amount of dangerous substances, and to the specific work-place., The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.

Environmental

No special environmental precautions required.

09

Physical and Chemical Properties

Appearance, physical state, melting point, boiling point, and material characteristics

Physical State
solid
Physical State Data
solid
State Under Standard Conditions
---
Appearance
---
Colour
---
Colour Intensity
---
Form
crystalline
Odor
No data available
Odor Threshold
No data available
Ph
No data available
Melting Point
150 - 152 °C
Boiling Point
No data available
Flash Point
No data available
Freezing Point
---
Softening Point
---
Solidification Point
---
Cloud Point
---
Crystallisation Point
---
Relative Evaporation Rate
---
Evaporation Rate
No data available
Vapor Pressure
No data available
Vapor Density
No data available
Relative Density
No data available
Bulk Density
---
Density
---
Flammability
No data available
Upper Explosive Limit
No data available
Lower Explosive Limit
No data available
Explosive Limits
---
Auto Ignition Temperature
No data available
Decomposition Temperature
No data available
Solubility
---
Partition Coefficient
No data available
Solubility In Water
No data available
Solubility In Fat
---
Molecular Weight
---
Voc Content
---
Metal Corrosion
---
Dynamic Viscosity
---
Kinematic Viscosity
---
Properties Status
---
10

Stability and Reactivity

Chemical stability, hazardous reactions, and incompatible materials

Stability

Stable under recommended storage conditions.

Reactivity

No data available

Hazardous reactions

No data available

Avoid

Exposure to moisture

Incompatible

Bases, Oxidizing agents

Decomposition

Other decomposition products - No data available. In the event of fire: see section 5

12

Ecological Information

Environmental toxicity, biodegradation, and bioaccumulation data

The data for this section has not been processed yet.

13

Disposal Considerations

Waste treatment methods, disposal recommendations, and waste codes

The data for this section has not been processed yet.

14

Transport Information

UN numbers, shipping names, transport classes, and regulatory requirements

15

Regulatory Information

Chemical regulations, safety assessments, and compliance status

The data for this section has not been processed yet.

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Frequently Asked Questions

Common questions about safety, handling, and properties

What is the hazard signal word for Trizma® hydrochloride?

The signal word is no signal word.

What is the physical form of Trizma® hydrochloride?

Trizma® hydrochloride is a solid . It has no data available odor.

What is Trizma® hydrochloride used for?

Laboratory chemicals, Manufacture of substances

What is the melting point of Trizma® hydrochloride?

The melting point is 150 - 152 °C and the boiling point is No data available.