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Safety Data Sheet EN

Retinoic acid

CAS 302-79-4

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01

Identification

Product identifiers, regulatory numbers, and supplier information

Product Information

Product Name
Retinoic acid
Product Code
R2625
Chemical Name
Retinoic acid

Regulatory Identifiers

CAS Number
302-79-4 Check regulations →

Identified Uses

Laboratory chemicals, Manufacture of substances

Manufacturers & Suppliers

M

Merck Life Science BV

manufacturer

Ildefonse Vandammestraat 5/7B, B-1560 HOEILAART

+32 (0)3 899-1301

Emergency Contacts

CHEMTREC

+(32) 28 083237

Anti-poison centre

070 245245

02

Hazard Identification

GHS classification, signal word, pictograms, and hazard statements

Classified danger

Hazard Classifications

Acute Tox. Cat. 4 H302
Skin Irrit. Cat. 2 H315
Repr. Cat. 1B H360FD
Aquatic Acute Cat. 1 H400
Aquatic Chronic Cat. 1 H410

GHS Pictograms

GHS07 - Health hazard

GHS07

GHS08 - Serious health hazard

GHS08

GHS09 - Environmental hazard

GHS09

Hazard Statements

H302 Harmful if swallowed.
H315 Causes skin irritation.
H360FD May damage fertility. May damage the unborn child.
H410 Very toxic to aquatic life with long lasting effects.

Precautionary Statements

P202 Do not handle until all safety precautions have been read and understood.
P264 Wash skin thoroughly after handling.
P273 Avoid release to the environment.
P301 + P312 IF SWALLOWED: Call a POISON CENTER/ doctor if you feel unwell.
P302 + P352 IF ON SKIN: Wash with plenty of water.
P308 + P313 IF exposed or concerned: Get medical advice/ attention.

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03

Composition / Information on Ingredients

Chemical components, concentration ranges, and hazardous substance identification

Type substance
Chemical Name CAS Number Concentration Hazardous
Vitamin A acid EC: 206-129-0 302-79-4 100% Yes
04

First Aid Measures

Emergency procedures for chemical exposure incidents

Inhalation

After inhalation: fresh air. Call in physician.

Skin contact

In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with water/ shower. Consult a physician.

Eye contact

After eye contact: rinse out with plenty of water. Call in ophthalmologist. Remove contact lenses.

Ingestion

After swallowing: immediately make victim drink water (two glasses at most). Consult a physician.

05

Firefighting Measures

Extinguishing media, specific hazards, and firefighter protection

Suitable media

Water Foam Carbon dioxide (CO2) Dry powder

Unsuitable media

For this substance/mixture no limitations of extinguishing agents are given.

Specific hazards

Carbon oxides. Combustible. Development of hazardous combustion gases or vapours possible in the event of fire.

Instructions

Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.

Firefighter Protection

Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.

06

Accidental Release Measures

Spill cleanup procedures, containment, and environmental protection

Emergency procedures

Avoid inhalation of dusts. Avoid substance contact. Ensure adequate ventilation. Evacuate the danger area, observe emergency procedures, consult an expert.

Environmental

Do not let product enter drains.

Cleanup methods

Take up carefully. Clean up affected area.

—

Related Products

Similar products with comparable safety profiles

07

Handling and Storage

Safe handling precautions, storage conditions, and workplace requirements

Handling

Work under hood. Do not inhale substance/mixture.

Storage

Tightly closed. Dry. Keep in a well-ventilated place. Keep locked up or in an area accessible only to qualified or authorised persons.

Hygiene

Immediately change contaminated clothing. Apply preventive skin protection. Wash hands and face after working with substance.

08

Exposure Controls / PPE

Occupational exposure limits, engineering controls, and protective equipment

Hands

Full contact: Material: Nitrile rubber, Minimum layer thickness: 0,11 mm, Break through time: 480 min, Material tested: KCL 741 Dermatril® L. Splash contact: Material: Nitrile rubber, Minimum layer thickness: 0,11 mm, Break through time: 480 min, Material tested: KCL 741 Dermatril® L. This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN 16523-1 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell, Internet: www.kcl.de).

Eyes

Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Safety glasses

Respiratory

required when dusts are generated. Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system. Recommended Filter type: Filter type P3. The entrepreneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer. These measures have to be properly documented.

Skin/Body

protective clothing

Environmental

Do not let product enter drains.

09

Physical and Chemical Properties

Appearance, physical state, melting point, boiling point, and material characteristics

Upper Explosive Limit
---
Flash Point
Not applicable
State Under Standard Conditions
---
Physical State
powder
Dynamic Viscosity
---
Decomposition Temperature
---
Partition Coefficient
---
Crystallisation Point
---
Molecular Weight
---
Solidification Point
---
Freezing Point
---
Appearance
---
Relative Density
---
Auto Ignition Temperature
---
Colour Intensity
---
Flammability
---
Odor
---
Cloud Point
---
Solubility In Fat
---
Vapor Pressure
---
Odor Threshold
---
Properties Status
---
Solubility
---
Vapor Density
---
Evaporation Rate
---
Physical State Data
solid
Relative Evaporation Rate
---
Colour
---
Voc Content
---
Lower Explosive Limit
---
Ph
---
Form
---
Metal Corrosion
---
Density
---
Boiling Point
---
Bulk Density
---
Kinematic Viscosity
---
Explosive Limits
---
Solubility In Water
---
Softening Point
---
Melting Point
Melting point/ range: 180 - 181 °C - lit.
10

Stability and Reactivity

Chemical stability, hazardous reactions, and incompatible materials

Stability

The product is chemically stable under standard ambient conditions (room temperature).

Reactivity

The following applies in general to flammable organic substances and mixtures: in correspondingly fine distribution, when whirled up a dust explosion potential may generally be assumed.

Hazardous reactions

Violent reactions possible with: Oxidizing agents, Bases

Avoid

Light.

Incompatible

No data available

Decomposition

In the event of fire: see section 5

12

Ecological Information

Environmental toxicity, biodegradation, and bioaccumulation data

The data for this section has not been processed yet.

13

Disposal Considerations

Waste treatment methods, disposal recommendations, and waste codes

The data for this section has not been processed yet.

14

Transport Information

UN numbers, shipping names, transport classes, and regulatory requirements

UN Number
3077
Shipping Name
ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S. (Vitamin A acid)
Transport Class
9
Packing Group
III
15

Regulatory Information

Chemical regulations, safety assessments, and compliance status

The data for this section has not been processed yet.

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Frequently Asked Questions

Common questions about safety, handling, and properties

What is the hazard signal word for Retinoic acid?

The signal word is danger.

What is the physical form of Retinoic acid?

Retinoic acid is a powder .

What is Retinoic acid used for?

Laboratory chemicals, Manufacture of substances

What are the hazard statements for Retinoic acid?

This substance has 4 hazard statements:

  • H302: Harmful if swallowed.
  • H315: Causes skin irritation.
  • H360FD: May damage fertility. May damage the unborn child.
  • H410: Very toxic to aquatic life with long lasting effects.

What is the melting point of Retinoic acid?

The melting point is Melting point/ range: 180 - 181 °C - lit. .