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Safety Data Sheet EN

All-Trans Retinoic Acid

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01

Identification

Product identifiers, regulatory numbers, and supplier information

Product Information

Product Name
All-Trans Retinoic Acid
Product Code
DX21097
Chemical Name
(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenoic acid
Synonyms
ATRA; NSC 122758; Retinoic acid; Trans retinoic acid; Tretinoin; Vitamin A acid;

Regulatory Identifiers

CAS Number
N/A

Identified Uses

Laboratory chemicals

Uses advised against

No information available

Manufacturers & Suppliers

S

STEMCELL Technologies SARL

manufacturer

40 Rue des Berges, Miniparc Polytec, Bâtiment Sirocco, 38000 Grenoble, France

+33 (0) 4 76 04 75 30

S

STEMCELL Technologies Germany GmbH

manufacturer

Stolberger Str. 200, 50933, Köln, Germany

+33 (0) 4 76 04 75 30

S

STEMCELL Technologies UK Ltd.

manufacturer

Building 7100, Cambridge Research Park, Beach Drive, Waterbeach, Cambridge, UK, CB25 9TL

+33 (0) 4 76 04 75 30

Emergency Contacts

Emergency Contact

112

02

Hazard Identification

GHS classification, signal word, pictograms, and hazard statements

Classified danger

Hazard Classifications

Skin Irrit. Cat. 2 H315
Repr. Cat. 1B H360
Aquatic Acute Cat. 1 H400
Aquatic Chronic Cat. 1 H410

GHS Pictograms

GHS07 - Health hazard

GHS07

GHS08 - Serious health hazard

GHS08

GHS09 - Environmental hazard

GHS09

Hazard Statements

H315 Causes skin irritation
H360 May damage fertility or the unborn child
H410 Very toxic to aquatic life with long lasting effects

Precautionary Statements

P201 Obtain special instructions before use
P202 Do not handle until all safety precautions have been read and understood
P280 Wear protective gloves/protective clothing/eye protection/face protection
P308 + P313 IF exposed or concerned: Get medical advice/attention
P321 Specific treatment (see .? on this label)

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03

Composition / Information on Ingredients

Chemical components, concentration ranges, and hazardous substance identification

Type substance
Chemical Name CAS Number Concentration Hazardous
(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenoic acid EC: 206-129-0 302-79-4 100% Yes
04

First Aid Measures

Emergency procedures for chemical exposure incidents

Inhalation

Remove to fresh air. Get medical attention immediately if symptoms occur.

Skin contact

Wash off immediately with soap and plenty of water for at least 15 minutes. Get medical attention if irritation develops and persists.

Eye contact

Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Keep eye wide open while rinsing. Remove contact lenses, if present and easy to do. Continue rinsing. Get medical attention if irritation develops and persists.

Ingestion

Clean mouth with water and drink afterwards plenty of water. Never give anything by mouth to an unconscious person. Do NOT induce vomiting. Call a physician.

Medical Treatment

Treat symptomatically.

05

Firefighting Measures

Extinguishing media, specific hazards, and firefighter protection

Suitable media

Use extinguishing measures that are appropriate to local circumstances and the surrounding environment.

Unsuitable media

No information available.

Specific hazards

No information available.

Firefighter Protection

Firefighters should wear self-contained breathing apparatus and full firefighting turnout gear. Use personal protection equipment.

06

Accidental Release Measures

Spill cleanup procedures, containment, and environmental protection

Emergency procedures

Avoid contact with skin, eyes or clothing. Ensure adequate ventilation. Use personal protective equipment as required.

Environmental

Prevent further leakage or spillage if safe to do so.

Cleanup methods

Take up mechanically, placing in appropriate containers for disposal.

—

Related Products

Similar products with comparable safety profiles

07

Handling and Storage

Safe handling precautions, storage conditions, and workplace requirements

Handling

Handle in accordance with good industrial hygiene and safety practice. Avoid contact with skin, eyes or clothing. Do not eat, drink or smoke when using this product. Remove contaminated clothing and shoes. Take off contaminated clothing and wash before reuse.

Storage

Store locked up. Store in accordance with information listed on the Product Information Sheet (PIS).

Hygiene

Do not eat, drink or smoke when using this product. Wash hands before breaks and immediately after handling the product. Wear suitable gloves and eye/face protection.

08

Exposure Controls / PPE

Occupational exposure limits, engineering controls, and protective equipment

Hands

Wear suitable gloves. Impervious gloves.

Eyes

No special protective equipment required.

Respiratory

No protective equipment is needed under normal use conditions. If exposure limits are exceeded or irritation is experienced, ventilation and evacuation may be required.

Skin/Body

Wear suitable protective clothing. Long sleeved clothing.

Environmental

No information available.

09

Physical and Chemical Properties

Appearance, physical state, melting point, boiling point, and material characteristics

Language Code
---
Physical State
Solid
Physical State Data
solid
State Under Standard Conditions
---
Appearance
Crystalline
Colour
No information available
Colour Intensity
---
Form
---
Odor
No data available.
Odor Threshold
No data available
Ph
No data available
Melting Point
178 °C / (352.4 °F)
Boiling Point
No data available
Flash Point
No data available
Freezing Point
---
Softening Point
---
Solidification Point
---
Cloud Point
---
Crystallisation Point
---
Relative Evaporation Rate
---
Evaporation Rate
No data available
Vapor Pressure
No data available
Vapor Density
No data available
Relative Density
No data available
Bulk Density
---
Density
---
Flammability
Product is not flammable.
Upper Explosive Limit
No data available
Lower Explosive Limit
No data available
Explosive Limits
---
Auto Ignition Temperature
No data available
Decomposition Temperature
No data available
Solubility
No data available
Partition Coefficient
No data available
Solubility In Water
No data available
Solubility In Fat
---
Molecular Weight
300.4
Voc Content
---
Metal Corrosion
---
Dynamic Viscosity
No data available
Kinematic Viscosity
No data available
Properties Status
---
10

Stability and Reactivity

Chemical stability, hazardous reactions, and incompatible materials

Stability

Stable under recommended transport or storage conditions.

Reactivity

No information available.

Hazardous reactions

None under normal processing.

Avoid

None known based on information supplied.

Incompatible

Strong oxidizing agents.

Decomposition

Carbon dioxide (CO2). Carbon monoxide.

12

Ecological Information

Environmental toxicity, biodegradation, and bioaccumulation data

12.1. Toxicity

Ecotoxicity Very toxic to aquatic life with long lasting effects. Unknown aquatic toxicity Contains 0 % of components with unknown hazards to the aquatic environment. ## Product Information

Very toxic to aquatic life with long lasting effects.

12.2. Persistence and degradability

Persistence and degradability No information available.

No information available.

12.3. Bioaccumulative potential

Bioaccumulation No information available.

No information available.

12.4. Mobility in soil

Mobility in soil No information available.

No information available.

12.5. Results of PBT and vPvB assessment

PBT and vPvB assessment No information available.

No information available.

12.6. Other adverse effects

Other adverse effects No information available.

No information available.

13

Disposal Considerations

Waste treatment methods, disposal recommendations, and waste codes

Disposal

Dispose of in accordance with local regulations. Dispose of waste in accordance with environmental legislation.

14

Transport Information

UN numbers, shipping names, transport classes, and regulatory requirements

UN Number
3077
Shipping Name
ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S. (all-trans Retinoic Acid)
Transport Class
9
Packing Group
III
15

Regulatory Information

Chemical regulations, safety assessments, and compliance status

This safety data sheet was created pursuant to the requirements of: Regulation (EC) No. 1907/2006 and Regulation (EC) No. 1272/2008

Chemical Safety Assessment Not performed
?

Frequently Asked Questions

Common questions about safety, handling, and properties

What other names is All-Trans Retinoic Acid known by?

All-Trans Retinoic Acid is also known as: ATRA; NSC 122758; Retinoic acid; Trans retinoic acid; Tretinoin; Vitamin A acid;

What is the hazard signal word for All-Trans Retinoic Acid?

The signal word is danger.

What is the physical form of All-Trans Retinoic Acid?

All-Trans Retinoic Acid is a solid appearing as crystalline with no information available color. It has no data available. odor.

What is the solubility of All-Trans Retinoic Acid?

No data available

What is All-Trans Retinoic Acid used for?

Laboratory chemicals

What are the hazard statements for All-Trans Retinoic Acid?

This substance has 3 hazard statements:

  • H315: Causes skin irritation
  • H360: May damage fertility or the unborn child
  • H410: Very toxic to aquatic life with long lasting effects

What is the melting point of All-Trans Retinoic Acid?

The melting point is 178 °C / (352.4 °F) and the boiling point is No data available.