NextSDS Logo
Safety Data Sheet EN

Letrozole

CAS 112809-51-5

Get a free compliance audit

Upload your SDS inventory and get a detailed compliance report.

Get Free Audit
01

Identification

Product identifiers, regulatory numbers, and supplier information

Product Information

Product Name
Letrozole
Product Code
L6545

Regulatory Identifiers

CAS Number
112809-51-5 Check regulations →

Identified Uses

Laboratory chemicals, Manufacture of substances

Manufacturers & Suppliers

M

Merck Life Science BV

manufacturer

Ildefonse Vandammestraat 5/7B B-1560 HOEILAART

+32 (0)3 899-1301

Emergency Contacts

CHEMTREC

+(32) 28 083237

Anti-poison centre

070 245245

02

Hazard Identification

GHS classification, signal word, pictograms, and hazard statements

Classified warning

Hazard Classifications

Repr. Cat. 2 H361fd
STOT RE Cat. 2 H373

GHS Pictograms

GHS08 - Serious health hazard

GHS08

Hazard Statements

H361fd Suspected of damaging fertility. Suspected of damaging the unborn child.
H373 May cause damage to organs through prolonged or repeated exposure.

Precautionary Statements

P202 Do not handle until all safety precautions have been read and understood.
P260 Do not breathe dust.
P280 Wear protective gloves/ protective clothing/ eye protection/ face protection.
P308 + P313 IF exposed or concerned: Get medical advice/ attention.
P405 Store locked up.
P501 Dispose of contents/ container to an approved waste disposal plant.

Get a free compliance audit

Upload your SDS inventory and get a detailed compliance report

Free Audit
03

Composition / Information on Ingredients

Chemical components, concentration ranges, and hazardous substance identification

Type substance
Chemical Name CAS Number Concentration Hazardous
Letrozole 112809-51-5 100% Yes
04

First Aid Measures

Emergency procedures for chemical exposure incidents

Inhalation

After inhalation: fresh air. Call in physician.

Skin contact

Take off immediately all contaminated clothing. Rinse skin with water/ shower. Consult a physician.

Eye contact

After eye contact: rinse out with plenty of water. Call in ophthalmologist. Remove contact lenses.

Ingestion

After swallowing: immediately make victim drink water (two glasses at most). Consult a physician.

05

Firefighting Measures

Extinguishing media, specific hazards, and firefighter protection

Suitable media

Water, Foam, Carbon dioxide (CO2), Dry powder

Unsuitable media

For this substance/mixture no limitations of extinguishing agents are given.

Specific hazards

Carbon oxides, Nitrogen oxides (NOx). Combustible. Development of hazardous combustion gases or vapours possible in the event of fire.

Instructions

Suppress (knock down) gases/vapours/mists with a water spray jet.

Firefighter Protection

Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.

06

Accidental Release Measures

Spill cleanup procedures, containment, and environmental protection

Emergency procedures

Avoid inhalation of dusts. Avoid substance contact. Ensure adequate ventilation. Evacuate the danger area, observe emergency procedures, consult an expert.

Environmental

Do not let product enter drains.

Cleanup methods

Take up dry. Clean up affected area.

Related Products

Similar products with comparable safety profiles

07

Handling and Storage

Safe handling precautions, storage conditions, and workplace requirements

Handling

Work under hood. Do not inhale substance/mixture.

Storage

Tightly closed. Dry. Keep locked up or in an area accessible only to qualified or authorised persons.

Hygiene

Change contaminated clothing. Preventive skin protection recommended. Wash hands after working with substance.

08

Exposure Controls / PPE

Occupational exposure limits, engineering controls, and protective equipment

Hands

Full contact Material: Nitrile rubber Minimum layer thickness: 0,11 mm Break through time: 480 min Material tested:KCL 741 Dermatril® L. Splash contact Material: Nitrile rubber Minimum layer thickness: 0,11 mm Break through time: 480 min Material tested:KCL 741 Dermatril® L. This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN 16523-1 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell, Internet: www.kcl.de).

Eyes

Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Safety glasses

Respiratory

required when dusts are generated. Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system. Recommended Filter type: Filter type P3. The entrepeneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer. These measures have to be properly documented.

Skin/Body

protective clothing

Environmental

Do not let product enter drains.

09

Physical and Chemical Properties

Appearance, physical state, melting point, boiling point, and material characteristics

Odor
No data available
Softening Point
---
Bulk Density
---
Decomposition Temperature
No data available
State Under Standard Conditions
---
Partition Coefficient
log Pow: ca.0,4 at 25 °C
Crystallisation Point
---
Molecular Weight
---
Dynamic Viscosity
No data available
Freezing Point
---
Kinematic Viscosity
No data available
Physical State Data
solid
Ph
No data available
Flash Point
Not applicable
Odor Threshold
---
Properties Status
---
Vapor Pressure
No data available
Melting Point
181 - 183 °C
Voc Content
---
Colour Intensity
---
Solubility In Water
No data available
Vapor Density
---
Form
---
Density
No data available
Solubility In Fat
---
Upper Explosive Limit
---
Appearance
---
Auto Ignition Temperature
No data available
Colour
white
Evaporation Rate
---
Boiling Point
No data available
Cloud Point
---
Metal Corrosion
---
Physical State
powder
Solidification Point
---
Flammability
---
Solubility
dimethyl sulfoxide 50 g/l - soluble
Relative Density
No data available
Explosive Limits
---
Lower Explosive Limit
---
Relative Evaporation Rate
---
10

Stability and Reactivity

Chemical stability, hazardous reactions, and incompatible materials

Stability

The product is chemically stable under standard ambient conditions (room temperature) .

Reactivity

The following applies in general to flammable organic substances and mixtures: in correspondingly fine distribution, when whirled up a dust explosion potential may generally be assumed.

Hazardous reactions

No data available

Avoid

no information available

Incompatible

Strong oxidizing agents

Decomposition

In the event of fire: see section 5

12

Ecological Information

Environmental toxicity, biodegradation, and bioaccumulation data

The data for this section has not been processed yet.

13

Disposal Considerations

Waste treatment methods, disposal recommendations, and waste codes

The data for this section has not been processed yet.

14

Transport Information

UN numbers, shipping names, transport classes, and regulatory requirements

Shipping Name
Not dangerous goods
15

Regulatory Information

Chemical regulations, safety assessments, and compliance status

The data for this section has not been processed yet.

?

Frequently Asked Questions

Common questions about safety, handling, and properties

What is the hazard signal word for Letrozole?

The signal word is warning.

What is the physical form of Letrozole?

Letrozole is a powder with white color. It has no data available odor.

What is the solubility of Letrozole?

dimethyl sulfoxide 50 g/l - soluble

What is Letrozole used for?

Laboratory chemicals, Manufacture of substances

What are the hazard statements for Letrozole?

This substance has 2 hazard statements:

  • H361fd: Suspected of damaging fertility. Suspected of damaging the unborn child.
  • H373: May cause damage to organs through prolonged or repeated exposure.

What is the melting point of Letrozole?

The melting point is 181 - 183 °C and the boiling point is No data available.