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Safety Data Sheet EN

Spironolactone

CAS 52-01-7

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01

Identification

Product identifiers, regulatory numbers, and supplier information

Product Information

Product Name
Spironolactone
Product Code
S3378
Chemical Name
Spironolactone

Regulatory Identifiers

CAS Number
52-01-7 Check regulations →
REACH No.
A registration number is not available for this substance as the substance or its uses are exempted from registration or the annual tonnage does not require a registration.

Identified Uses

Laboratory chemicals, Manufacture of substances

Manufacturers & Suppliers

S

Sigma

manufacturer

S

Sigma-Aldrich Chemie GmbH

manufacturer

Eschenstrasse 5, D-82024 TAUFKIRCHEN

+49 (0)89 6513-1130

Emergency Contacts

CHEMTREC Deutschland

0800 181 7059

CHEMTREC weltweit

+49 (0)696 43508409

02

Hazard Identification

GHS classification, signal word, pictograms, and hazard statements

Classified danger

Hazard Classifications

Carc. Cat. 2 H351
Repr. Cat. 1B H360FD
STOT RE Cat. 2 H373

GHS Pictograms

GHS08 - Serious health hazard

GHS08

Hazard Statements

H351 Suspected of causing cancer.
H360FD May damage fertility. May damage the unborn child.
H373 May cause damage to organs through prolonged or repeated exposure.

Precautionary Statements

P202 Do not handle until all safety precautions have been read and understood.
P260 Do not breathe dust.
P280 Wear protective gloves/ protective clothing/ eye protection/ face protection.
P308 + P313 IF exposed or concerned: Get medical advice/ attention.
P405 Store locked up.
P501 Dispose of contents/ container to an approved waste disposal plant.

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03

Composition / Information on Ingredients

Chemical components, concentration ranges, and hazardous substance identification

Type substance
Chemical Name CAS Number Concentration Hazardous
Spirolactone EC: 200-133-6 52-01-7 100% Yes
04

First Aid Measures

Emergency procedures for chemical exposure incidents

Inhalation

After inhalation: fresh air. Call in physician.

Skin contact

In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with water/ shower. Consult a physician.

Eye contact

After eye contact: rinse out with plenty of water. Call in ophthalmologist. Remove contact lenses.

Ingestion

After swallowing: immediately make victim drink water (two glasses at most). Consult a physician.

05

Firefighting Measures

Extinguishing media, specific hazards, and firefighter protection

Suitable media

Water, Foam, Carbon dioxide (CO2), Dry powder

Unsuitable media

For this substance/mixture no limitations of extinguishing agents are given.

Specific hazards

Carbon oxides, Sulphur oxides. Combustible. Development of hazardous combustion gases or vapours possible in the event of fire.

Instructions

Suppress (knock down) gases/vapours/mists with a water spray jet.

Firefighter Protection

Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.

06

Accidental Release Measures

Spill cleanup procedures, containment, and environmental protection

Emergency procedures

Avoid inhalation of dusts. Avoid substance contact. Ensure adequate ventilation. Evacuate the danger area, observe emergency procedures, consult an expert.

Environmental

Do not let product enter drains.

Cleanup methods

Take up carefully. Clean up affected area.

Related Products

Similar products with comparable safety profiles

07

Handling and Storage

Safe handling precautions, storage conditions, and workplace requirements

Handling

Work under hood. Do not inhale substance/mixture.

Storage

Tightly closed. Dry. Keep in a well-ventilated place. Keep locked up or in an area accessible only to qualified or authorised persons.

Hygiene

Immediately change contaminated clothing. Apply preventive skin protection. Wash hands and face after working with substance.

08

Exposure Controls / PPE

Occupational exposure limits, engineering controls, and protective equipment

Eyes

Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Safety glasses

Respiratory

required when dusts are generated. Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system. Recommended Filter type: Filter type P3. The entrepreneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer. These measures have to be properly documented.

Skin/Body

protective clothing

Environmental

Do not let product enter drains.

09

Physical and Chemical Properties

Appearance, physical state, melting point, boiling point, and material characteristics

Boiling Point
No data available
Density
No data available
Odor Threshold
---
Voc Content
---
Solubility In Fat
---
Dynamic Viscosity
No data available
Lower Explosive Limit
No data available
Partition Coefficient
No data available
Solubility
---
Physical State
powder
Vapor Pressure
No data available
Melting Point
Melting point/ range: 207 - 208 °C - lit.
Solidification Point
---
Appearance
---
Crystallisation Point
---
Colour
white
Evaporation Rate
---
Softening Point
---
Bulk Density
---
Ph
No data available
Properties Status
---
Flash Point
Not applicable
Auto Ignition Temperature
No data available
Explosive Limits
---
Metal Corrosion
---
Colour Intensity
---
Solubility In Water
No data available
Freezing Point
---
Flammability
No data available
Relative Evaporation Rate
---
Cloud Point
---
Form
---
Relative Density
No data available
Vapor Density
---
Physical State Data
solid
Odor
No data available
Upper Explosive Limit
No data available
Decomposition Temperature
No data available
State Under Standard Conditions
---
Molecular Weight
---
Kinematic Viscosity
No data available
10

Stability and Reactivity

Chemical stability, hazardous reactions, and incompatible materials

Stability

The product is chemically stable under standard ambient conditions (room temperature).

Reactivity

The following applies in general to flammable organic substances and mixtures: in correspondingly fine distribution, when whirled up a dust explosion potential may generally be assumed.

Hazardous reactions

Violent reactions possible with: Strong oxidizing agents

Avoid

no information available

Incompatible

No data available

Decomposition

In the event of fire: see section 5

12

Ecological Information

Environmental toxicity, biodegradation, and bioaccumulation data

The data for this section has not been processed yet.

13

Disposal Considerations

Waste treatment methods, disposal recommendations, and waste codes

The data for this section has not been processed yet.

14

Transport Information

UN numbers, shipping names, transport classes, and regulatory requirements

15

Regulatory Information

Chemical regulations, safety assessments, and compliance status

The data for this section has not been processed yet.

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Frequently Asked Questions

Common questions about safety, handling, and properties

What is the hazard signal word for Spironolactone?

The signal word is danger.

What is the physical form of Spironolactone?

Spironolactone is a powder with white color. It has no data available odor.

What is Spironolactone used for?

Laboratory chemicals, Manufacture of substances

What are the hazard statements for Spironolactone?

This substance has 3 hazard statements:

  • H351: Suspected of causing cancer.
  • H360FD: May damage fertility. May damage the unborn child.
  • H373: May cause damage to organs through prolonged or repeated exposure.

What is the melting point of Spironolactone?

The melting point is Melting point/ range: 207 - 208 °C - lit. and the boiling point is No data available.