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Safety Data Sheet EN

Histological Fixative (Formal saline) GURR® Formaldehyde 4% (M/V)

CAS 50-00-0

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01

Identification

Product identifiers, regulatory numbers, and supplier information

Product Information

Product Name
Histological Fixative (Formal saline) GURR® Formaldehyde 4% (M/V)
Product Code
36136

Regulatory Identifiers

CAS Number
50-00-0 Check regulations →

Identified Uses

Scientific research and development

Uses advised against

All uses other than scientific research and development

Manufacturers & Suppliers

V

VWR International Ltd.

national supplier

Hunter Boulevard, Magna Park, Lutterworth, LE17 4XN, UK

0800 22 33 44

Emergency Contacts

CareChem24

+44 (0) 1270 502894

02

Hazard Identification

GHS classification, signal word, pictograms, and hazard statements

Classified danger

Hazard Classifications

Acute Tox. Cat. 4 H302 + H312 + H332
Skin Irrit. Cat. 2 H315
Skin Sens. Cat. 1 H317
Eye Irrit. Cat. 2 H319
Muta. Cat. 2 H341
Carc. Cat. 1B H350
STOT SE Cat. 2 H371

GHS Pictograms

GHS07 - Health hazard

GHS07

GHS08 - Serious health hazard

GHS08

Hazard Statements

H302 + H312 + H332 Harmful if swallowed, in contact with skin or if inhaled.
H315 Causes skin irritation.
H317 May cause an allergic skin reaction.
H319 Causes serious eye irritation.
H341 Suspected of causing genetic defects.
H350 May cause cancer.
H371 May cause damage to organs.

Precautionary Statements

P201 Obtain special instructions before use.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301 + P330 + P331 IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
P302 + P352 IF ON SKIN: Wash with plenty of water.
P304 + P340 IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing
P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P308 + P311 IF exposed or concerned: Call a POISON CENTER/doctor.

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03

Composition / Information on Ingredients

Chemical components, concentration ranges, and hazardous substance identification

Type mixture
Chemical Name CAS Number Concentration Hazardous
Formaldehyde EC: 200-001-8 50-00-0 3 - 5% Yes
Methanol EC: 200-659-6 67-56-1 1 - 3% Yes
04

First Aid Measures

Emergency procedures for chemical exposure incidents

Inhalation

Call a POISON CENTRE/doctor. Remove casualty to fresh air and keep warm and at rest. If breathing is irregular or stopped, administer artificial respiration.

Skin contact

After contact with skin, wash immediately with plenty of water and soap. Remove contaminated, saturated clothing immediately. In case of skin reactions, consult a physician.

Eye contact

In case of contact with eyes flush immediately with plenty of flowing water for 10 to 15 minutes holding eyelids apart and consult an ophthalmologist. Protect uninjured eye. Remove contact lenses, if present and easy to do. Continue rinsing.

Ingestion

If accidentally swallowed rinse the mouth with plenty of water (only if the person is conscious) and obtain immediate medical attention. Do NOT induce vomiting. Give nothing to eat or drink.

Immediate Medical Attention

Call a POISON CENTRE or doctor/physician if exposed or if you feel unwell. Obtain immediate medical attention if swallowed. Consult a physician in case of skin reactions. Consult an ophthalmologist after eye contact.

05

Firefighting Measures

Extinguishing media, specific hazards, and firefighter protection

Suitable media

The product itself does not burn. Co-ordinate fire-fighting measures to the fire surroundings.

Unsuitable media

no restriction

Specific hazards

In case of fire may be liberated: Pyrolysis products, toxic

Instructions

DO NOT fight fire when fire reaches explosives.

Firefighter Protection

Use water spray jet to protect personnel and to cool endangered containers.

06

Accidental Release Measures

Spill cleanup procedures, containment, and environmental protection

Emergency procedures

In case of major fire and large quantities: Remove persons to safety.

Environmental

Discharge into the environment must be avoided.

Cleanup methods

Collect in closed and suitable containers for disposal.

—

Related Products

Similar products with comparable safety profiles

07

Handling and Storage

Safe handling precautions, storage conditions, and workplace requirements

Handling

All work processes must always be designed so that the following is as low as possible: Inhalation, Skin contact, Eye contact.

Storage

Keep container tightly closed and in a well-ventilated place. Keep/Store only in original container.

Hygiene

Wash hands before breaks and after work. Avoid contact with eyes and skin. When using do not eat, drink or smoke.

08

Exposure Controls / PPE

Occupational exposure limits, engineering controls, and protective equipment

Engineering

Technical measures and the application of suitable work processes have priority over personal protection equipment. If handled uncovered, arrangements with local exhaust ventilation have to be used.

Hands

When handling with chemical substances, protective gloves must be worn with the CE-label including the four control digits. Recommended glove articles DIN-/EN-Norms EN ISO 374 In the case of wanting to use the gloves again, clean them before taking off and air them well. By short-term hand contact: Suitable material: NBR (Nitrile rubber), Thickness of the glove material: 0,12 mm, Breakthrough time: > 480 min, Recommended glove articles: VWR 112-0998. By long-term hand contact: Suitable material: NBR (Nitrile rubber), Thickness of the glove material: 0,38 mm, Breakthrough time: > 480 min, Recommended glove articles: VWR 112-1381.

Eyes

Eye glasses with side protection DIN-/EN-Norms EN 166. Recommendation: VWR 111-0432

Respiratory

Respiratory protection necessary at: aerosol or mist formation. Suitable respiratory protection apparatus: Full-/half-/quarter-face masks (EN 136/140). Recommendation: VWR 111-0206. Suitable material: A1. Recommendation: VWR 111-8930.

Skin/Body

Wear suitable protective clothing. When handling with chemical substances, protective clothing with CE-labels including the four control digits must be worn.

Environmental

no data available

09

Physical and Chemical Properties

Appearance, physical state, melting point, boiling point, and material characteristics

Language Code
---
Physical State
liquid
Physical State Data
liquid
State Under Standard Conditions
---
Appearance
---
Colour
colourless
Colour Intensity
---
Form
---
Odor
characteristic
Odor Threshold
---
Ph
3.5-4.5 (25 °C)
Melting Point
no data available
Boiling Point
no data available
Flash Point
no data available
Freezing Point
---
Softening Point
---
Solidification Point
---
Cloud Point
---
Crystallisation Point
---
Relative Evaporation Rate
---
Evaporation Rate
no data available
Vapor Pressure
no data available
Vapor Density
---
Relative Density
---
Bulk Density
no data available
Density
1.014 g/cm³ (20 °C)
Flammability
Not applicable
Upper Explosive Limit
no data available
Lower Explosive Limit
no data available
Explosive Limits
---
Auto Ignition Temperature
no data available
Decomposition Temperature
Not applicable
Solubility
---
Partition Coefficient
no data available
Solubility In Water
no data available
Solubility In Fat
---
Molecular Weight
---
Voc Content
---
Metal Corrosion
---
Dynamic Viscosity
no data available
Kinematic Viscosity
no data available
Properties Status
---
10

Stability and Reactivity

Chemical stability, hazardous reactions, and incompatible materials

Stability

The product is chemically stable under standard ambient conditions (room temperature).

Reactivity

no data available

Hazardous reactions

no data available

Avoid

no data available

Incompatible

no data available

Decomposition

no data available

12

Ecological Information

Environmental toxicity, biodegradation, and bioaccumulation data

12.1 Toxicity

Fish toxicity: Formaldehyde - LC50: 1.41 - 330 mg/l (96 h)

12.1 Toxicity

Fish toxicity: Methanol - LC50: 15000 - 29400 mg/l (96 h) - Poirier, S.H., M.L. Knuth, C.D. Anderson-Buchou, L.T. Brooke, A.R. Lima, and P.J. Shubat 1986. Comparative Toxicity of Methanol and N,N-Dimethylformamide to Freshwater Fish and Invertebrates. Bull.Environ.Contam.Toxicol. 37(4):615-621

12.1 Toxicity

Daphnia toxicity: Formaldehyde - LC50: 954 - 1160 mg/l (48 h) VWR THE CHEMICALS avantor delivered by VWR Formaldehyde - EC50: 5.8 - 29 mg/l (48 h)

12.1 Toxicity

Daphnia toxicity: Methanol - LC50: 2500 - 4810 mg/l (48 h) - Guilhermino, L., T. Diamantino, M.C. Silva, and A.M.V.M. Soares 2000. Acute Toxicity Test with Daphnia magna: An Alternative to Mammals in the Prescreening of Chemical Toxicity?. Ecotoxicol.Environ.Saf. 46(3):357-362

12.1 Toxicity

Daphnia toxicity: Methanol - EC50: 22200 - 46800 mg/l (48 h) - Randall, T.L., and P.V. Knopp 1980. Detoxification of Specific Organic Substances by Wet Oxidation. J.Water Pollut.Control Fed. 52(8):2117-2130

12.1 Toxicity

**Algae toxicity:** Methanol - EC50: 22 000 mg/l (96 h) - Pseudokirchneriella subcapitata - IUCLID

12.4 Mobility in soil

no data available

12.5 Results of PBT/vPvB assessment

The mixture does not contain a substance fulfilling the PBT criteria. The mixture does not contain a substance fulfilling the vPvB criteria.

The mixture does not contain any substances that meet the PBT or vPvB criteria.

12.6 Endocrine disrupting properties

This product does not contain a substance that has endocrine disrupting properties with respect to the environment.

The product does not contain a substance that has endocrine disrupting properties with respect to the environment.

12.7 Other adverse effects

no data available

no data available

13

Disposal Considerations

Waste treatment methods, disposal recommendations, and waste codes

Treatment

Dispose according to local legislation. Consult the appropriate local waste disposal expert about waste disposal.

Disposal

Dispose according to local legislation. Consult the appropriate local waste disposal expert about waste disposal.

14

Transport Information

UN numbers, shipping names, transport classes, and regulatory requirements

15

Regulatory Information

Chemical regulations, safety assessments, and compliance status

?

Frequently Asked Questions

Common questions about safety, handling, and properties

What is the hazard signal word for Histological Fixative (Formal saline) GURR® Formaldehyde 4% (M/V)?

The signal word is danger.

What is the physical form of Histological Fixative (Formal saline) GURR® Formaldehyde 4% (M/V)?

Histological Fixative (Formal saline) GURR® Formaldehyde 4% (M/V) is a liquid with colourless color. It has characteristic odor.

What is Histological Fixative (Formal saline) GURR® Formaldehyde 4% (M/V) used for?

Scientific research and development

What are the hazard statements for Histological Fixative (Formal saline) GURR® Formaldehyde 4% (M/V)?

This substance has 7 hazard statements:

  • H302 + H312 + H332: Harmful if swallowed, in contact with skin or if inhaled.
  • H315: Causes skin irritation.
  • H317: May cause an allergic skin reaction.
  • H319: Causes serious eye irritation.
  • H341: Suspected of causing genetic defects.
  • H350: May cause cancer.
  • H371: May cause damage to organs.

What is the melting point of Histological Fixative (Formal saline) GURR® Formaldehyde 4% (M/V)?

The melting point is no data available and the boiling point is no data available.