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Safety Data Sheet EN

N-(3-Dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride

CAS 25952-53-8

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01

Identification

Product identifiers, regulatory numbers, and supplier information

Product Information

Product Name
N-(3-Dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride
Product Code
E7750

Regulatory Identifiers

CAS Number
25952-53-8 Check regulations →

Identified Uses

Laboratory chemicals, Manufacture of substances

Manufacturers & Suppliers

S

Sigma-Aldrich Chemie GmbH

manufacturer

Eschenstrasse 5, D-82024 TAUFKIRCHEN

+49 (0)89 6513-1130

Emergency Contacts

CHEMTREC Deutschland

0800 181 7059

CHEMTREC weltweit

+49 (0)696 43508409

02

Hazard Identification

GHS classification, signal word, pictograms, and hazard statements

Classified danger

Hazard Classifications

Acute Tox. Cat. 4 H302
Acute Tox. Cat. 3 H311
Skin Irrit. Cat. 2 H315
Skin Sens. Cat. 1 H317
STOT RE Cat. 2 H373
Aquatic Acute Cat. 1 H400
Aquatic Chronic Cat. 1 H410

GHS Pictograms

GHS06 - Acute toxicity

GHS06

GHS08 - Serious health hazard

GHS08

GHS09 - Environmental hazard

GHS09

Hazard Statements

H302 Harmful if swallowed.
H311 Toxic in contact with skin.
H315 Causes skin irritation.
H317 May cause an allergic skin reaction.
H373 May cause damage to organs (Stomach, large intestine, lymph node) through prolonged or repeated exposure if swallowed.
H410 Very toxic to aquatic life with long lasting effects.

Precautionary Statements

P260 Do not breathe dust.
P273 Avoid release to the environment.
P280 Wear protective gloves/ protective clothing.
P301 + P312 IF SWALLOWED: Call a POISON CENTER/ doctor if you feel unwell.
P314 Get medical advice/ attention if you feel unwell.
IF ON SKIN: Wash with plenty of water. Call a POISON CENTER/ doctor if you feel unwell.

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03

Composition / Information on Ingredients

Chemical components, concentration ranges, and hazardous substance identification

Type substance
Chemical Name CAS Number Concentration Hazardous
1-(3-(Dimethylamino)propyl)-3-ethyl-carbodiimide hydrochloride EC: 247-361-2 25952-53-8 100% Yes
04

First Aid Measures

Emergency procedures for chemical exposure incidents

Inhalation

Fresh air. Call in physician.

Skin contact

Take off immediately all contaminated clothing. Rinse skin with water/ shower. Call a physician immediately.

Eye contact

Rinse out with plenty of water. Remove contact lenses.

Ingestion

Immediately make victim drink water (two glasses at most). Consult a physician.

05

Firefighting Measures

Extinguishing media, specific hazards, and firefighter protection

Suitable media

Water, Foam, Carbon dioxide (CO2), Dry powder

Unsuitable media

For this substance/mixture no limitations of extinguishing agents are given.

Specific hazards

Combustible. Development of hazardous combustion gases or vapours possible in the event of fire.

Instructions

Suppress (knock down) gases/vapors/mists with a water spray jet.

Firefighter Protection

Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.

06

Accidental Release Measures

Spill cleanup procedures, containment, and environmental protection

Emergency procedures

Avoid generation and inhalation of dusts in all circumstances. Avoid substance contact. Ensure adequate ventilation. Evacuate the danger area, observe emergency procedures, consult an expert.

Environmental

Do not let product enter drains.

Cleanup methods

Take up carefully. Clean up affected area.

—

Related Products

Similar products with comparable safety profiles

07

Handling and Storage

Safe handling precautions, storage conditions, and workplace requirements

Handling

For precautions see section 2.2.

Storage

Tightly closed. Dry. Keep in a well-ventilated place. Keep locked up or in an area accessible only to qualified or authorized persons.

08

Exposure Controls / PPE

Occupational exposure limits, engineering controls, and protective equipment

Hands

Full contact: Material: Nitrile rubber, Minimum layer thickness: 0,11 mm, Break through time: 480 min, Material tested: KCL 741 Dermatril® L. Splash contact: Material: Nitrile rubber, Minimum layer thickness: 0,11 mm, Break through time: 480 min, Material tested: KCL 741 Dermatril® L. This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN 16523-1 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell, Internet: www.kcl.de).

Eyes

Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Safety glasses

Respiratory

required when dusts are generated. Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system. Recommended Filter type: Filter type P3. The entrepreneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer. These measures have to be properly documented.

Skin/Body

protective clothing

Environmental

Do not let product enter drains.

09

Physical and Chemical Properties

Appearance, physical state, melting point, boiling point, and material characteristics

Language Code
---
Physical State
powder
Physical State Data
solid
State Under Standard Conditions
---
Appearance
---
Colour
white, to, off-white
Colour Intensity
---
Form
---
Odor
No data available
Odor Threshold
---
Ph
---
Melting Point
Melting point/range: 110 - 115 °C
Boiling Point
---
Flash Point
Not applicable
Freezing Point
---
Softening Point
---
Solidification Point
---
Cloud Point
---
Crystallisation Point
---
Relative Evaporation Rate
---
Evaporation Rate
---
Vapor Pressure
< 1,3 hPa at 20 °C - OECD Test Guideline 104
Vapor Density
---
Relative Density
1,004 at 20 °C - OECD Test Guideline 109
Bulk Density
---
Density
1,044 g/cm3 at 20 °C - OECD Test Guideline 109
Flammability
No data available
Upper Explosive Limit
---
Lower Explosive Limit
---
Explosive Limits
---
Auto Ignition Temperature
---
Decomposition Temperature
---
Solubility
---
Partition Coefficient
log Pow: -2,98 at 20 °C - OECD Test Guideline 107 - n-octanol/water Bioaccumulation is not expected.
Solubility In Water
1.000 g/l at 20 °C - OECD Test Guideline 105
Solubility In Fat
---
Molecular Weight
---
Voc Content
---
Metal Corrosion
---
Dynamic Viscosity
---
Kinematic Viscosity
---
Properties Status
---
10

Stability and Reactivity

Chemical stability, hazardous reactions, and incompatible materials

Stability

The product is chemically stable under standard ambient conditions (room temperature).

Reactivity

The following applies in general to flammable organic substances and mixtures: in correspondingly fine distribution, when whirled up a dust explosion potential may generally be assumed.

Hazardous reactions

In contact with nitrites, nitrates, nitrous acid possible liberation of nitrosamines! Violent reactions possible with: Oxidizing agents, Acid anhydrides, acid halides, acids

Avoid

no information available

Incompatible

nitrites, nitrates, nitrous acid, Oxidizing agents, Acid anhydrides, acid halides, acids

Decomposition

In the event of fire: see section 5

12

Ecological Information

Environmental toxicity, biodegradation, and bioaccumulation data

12.1 Toxicity

Toxicity to daphnia and other aquatic invertebrates EC50 - Daphnia magna (Water flea) - 0,41 mg/l - 48 h (ISO 6341)

12.1 Toxicity

Toxicity to fish static test LC50 - Cyprinus carpio (Carp) - 4,6 mg/l - 96 h (OECD Test Guideline 203)

12.1 Toxicity

Toxicity to bacteria EC50 - activated sludge - > 347 - < 470 mg/l - 3 h (OECD Test Guideline 209)

12.2 Persistence and degradability

12.2 Persistence and degradability

12.2 Persistence and degradability

Biodegradability aerobic Chemical oxygen demand - Exposure time 28 d Result: < 5 % - Not readily biodegradable. (OECD Test Guideline 301F)

12.3 Bioaccumulative potential

No data available

12.4 Mobility in soil

No data available

12.5 Results of PBT and vPvB assessment

This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.

The substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.

12.6 Endocrine disrupting properties

The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher.

The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher.

12.7 Other adverse effects

No data available

No data available

13

Disposal Considerations

Waste treatment methods, disposal recommendations, and waste codes

Disposal

See www.retrologistik.com for processes regarding the return of chemicals and containers, or contact us there if you have further questions.

14

Transport Information

UN numbers, shipping names, transport classes, and regulatory requirements

UN Number
2811
Shipping Name
TOXIC SOLID, ORGANIC, N.O.S. (1-(3-(Dimethylamino)propyl)-3-ethylcarbodiimide hydrochloride)
Transport Class
6.1
Packing Group
III
15

Regulatory Information

Chemical regulations, safety assessments, and compliance status

This material safety data sheet complies with the requirements of Regulation (EC) No. 1907/2006.

Chemical Safety Assessment Not performed
?

Frequently Asked Questions

Common questions about safety, handling, and properties

What is the hazard signal word for N-(3-Dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride?

The signal word is danger.

What is the physical form of N-(3-Dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride?

N-(3-Dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride is a powder with white, to, off-white color. It has no data available odor.

What is N-(3-Dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride used for?

Laboratory chemicals, Manufacture of substances

What are the hazard statements for N-(3-Dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride?

This substance has 6 hazard statements:

  • H302: Harmful if swallowed.
  • H311: Toxic in contact with skin.
  • H315: Causes skin irritation.
  • H317: May cause an allergic skin reaction.
  • H373: May cause damage to organs (Stomach, large intestine, lymph node) through prolonged or repeated exposure if swallowed.
  • H410: Very toxic to aquatic life with long lasting effects.

What is the melting point of N-(3-Dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride?

The melting point is Melting point/range: 110 - 115 °C .