Identification
Product identifiers, regulatory numbers, and supplier information
Product Information
- Product Name
- Afatinib (BIBW2992)
- Product Code
- S1011
Regulatory Identifiers
- CAS Number
- 850140-72-6 Check regulations →
Identified Uses
Laboratory chemicals, manufacture of substances.
Manufacturers & Suppliers
Selleck Chemicals
manufacturer
+1 832 582-8158
Emergency Contacts
Emergency Contact
+1 832 582-8158
Hazard Identification
GHS classification, signal word, pictograms, and hazard statements
Hazard Classifications
GHS Pictograms
GHS07
Hazard Statements
Precautionary Statements
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Composition / Information on Ingredients
Chemical components, concentration ranges, and hazardous substance identification
| Chemical Name | CAS Number | Concentration | Hazardous |
|---|---|---|---|
| (S,E)-N-(4-(3-chloro-4-fluorophenylamino)-7-(tetrahydrofuran-3-yloxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide | 850140-72-6 | --- | No |
First Aid Measures
Emergency procedures for chemical exposure incidents
Immediately relocate self or casualty to fresh air. If breathing is difficult, give cardiopulmonary resuscitation (CPR). Avoid mouth-to-mouth resuscitation.
Rinse skin thoroughly with large amounts of water. Remove contaminated clothing and shoes.
Remove any contact lenses, locate eye-wash station, and flush eyes immediately with large amounts of water. Separate eyelids with fingers to ensure adequate flushing.
Wash out mouth with water; Do NOT induce vomiting.
Immediate Medical Attention
Promptly call a physician.
Medical Treatment
Treat symptomatically.
Firefighting Measures
Extinguishing media, specific hazards, and firefighter protection
Use water spray, dry chemical, foam, and carbon dioxide fire extinguisher.
During combustion, may emit irritant fumes.
Firefighter Protection
Wear self-contained breathing apparatus and protective clothing.
Accidental Release Measures
Spill cleanup procedures, containment, and environmental protection
Use full personal protective equipment. Avoid breathing vapors, mist, dust or gas. Ensure adequate ventilation. Evacuate personnel to safe areas.
Try to prevent further leakage or spillage.
Absorb solutions with finely-powdered liquid-binding material; Decontaminate surfaces and equipment by scrubbing with alcohol
Materials: diatomite, universal binders
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Similar products with comparable safety profiles
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Handling and Storage
Safe handling precautions, storage conditions, and workplace requirements
Avoid inhalation, contact with eyes and skin. Avoid dust and aerosol formation.
Keep container tightly sealed in cool, well-ventilated area. Keep away from direct sunlight and sources of ignition. Store at -20°C (powder) or -80°C (in solvent)
Keep away from sources of ignition.
Exposure Controls / PPE
Occupational exposure limits, engineering controls, and protective equipment
Ensure adequate ventilation. Provide accessible safety shower and eye wash station.
Protective gloves.
Safety goggles with side-shields.
Suitable respirator.
Impervious clothing.
Keep the product away from drains, water courses or the soil. Clean spillages in a safe way as soon as possible.
Physical and Chemical Properties
Appearance, physical state, melting point, boiling point, and material characteristics
Stability and Reactivity
Chemical stability, hazardous reactions, and incompatible materials
Stable under recommended storage conditions.
No data available.
No data available.
No data available.
Strong acids/alkalis, strong oxidising/reducing agents.
Under fire conditions, may decompose and emit toxic fumes. Other decomposition products - no data available.
Ecological Information
Environmental toxicity, biodegradation, and bioaccumulation data
12.1 Toxicity
No data available.
12.2 Persistence and degradability
12.3 Bioaccumulative potential
12.4 Mobility in soil
No data available.
12.5 Results of PBT and vPvB assessment
PBT/vPvB assessment unavailable as chemical safety assessment not required or not conducted.
12.6 Other adverse effects
No data available.
Disposal Considerations
Waste treatment methods, disposal recommendations, and waste codes
Dispose substance in accordance with prevailing country, federal, state and local regulations.
Dispose substance in accordance with prevailing country, federal, state and local regulations.
Transport Information
UN numbers, shipping names, transport classes, and regulatory requirements
- UN Number
- 3077
- Shipping Name
- ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S.
- Transport Class
- 9
- Packing Group
- III
Regulatory Information
Chemical regulations, safety assessments, and compliance status
No data available.
Frequently Asked Questions
Common questions about safety, handling, and properties
What is the hazard signal word for Afatinib (BIBW2992)?
The signal word is warning.
What is the physical form of Afatinib (BIBW2992)?
Afatinib (BIBW2992) is a solid appearing as solid . It has no data available odor.
What is Afatinib (BIBW2992) used for?
Laboratory chemicals, manufacture of substances.
What are the hazard statements for Afatinib (BIBW2992)?
This substance has 3 hazard statements:
- H315: Causes skin irritation.
- H319: Causes serious eye irritation.
- H335: May cause respiratory irritation.
What is the melting point of Afatinib (BIBW2992)?
The melting point is No data available and the boiling point is No data available.