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Safety Data Sheet EN

Acetaminophen

CAS 103-90-2

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01

Identification

Product identifiers, regulatory numbers, and supplier information

Product Information

Product Name
Acetaminophen
Product Code
A5000

Regulatory Identifiers

CAS Number
103-90-2 Check regulations →

Identified Uses

Laboratory chemicals, Synthesis of substances

Manufacturers & Suppliers

S

Sigma-Aldrich Inc.

manufacturer

3050 SPRUCE ST, ST. LOUIS MO 63103, UNITED STATES

+1 314 771-5765

Emergency Contacts

CHEMTREC

800-424-9300

24 Hours/day; 7 Days/week

CHEMTREC

+1-703-527-3887

24 Hours/day; 7 Days/week

02

Hazard Identification

GHS classification, signal word, pictograms, and hazard statements

Classified warning

Hazard Classifications

Acute Tox. Cat. 4 H302

GHS Pictograms

GHS07 - Health hazard

GHS07

Hazard Statements

H302 Harmful if swallowed.

Precautionary Statements

P264 Wash skin thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P501 Dispose of contents/ container to an approved waste disposal plant.
IF SWALLOWED: Call a POISON CENTER/ doctor if you feel unwell. Rinse mouth.

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03

Composition / Information on Ingredients

Chemical components, concentration ranges, and hazardous substance identification

Type substance
Chemical Name CAS Number Concentration Hazardous
4'-hydroxyacetanilide 103-90-2 100% Yes
04

First Aid Measures

Emergency procedures for chemical exposure incidents

Inhalation

fresh air.

Skin contact

Take off immediately all contaminated clothing. Rinse skin with water/ shower.

Eye contact

rinse out with plenty of water. Remove contact lenses.

Ingestion

immediately make victim drink water (two glasses at most). Consult a physician.

05

Firefighting Measures

Extinguishing media, specific hazards, and firefighter protection

Suitable media

Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide. Water Foam Carbon dioxide (CO2) Dry powder

Unsuitable media

For this substance/mixture no limitations of extinguishing agents are given. For this substance/mixture no limitations of extinguishing agents are given.

Specific hazards

Combustible. Vapors are heavier than air and may spread along floors. Forms explosive mixtures with air on intense heating. Development of hazardous combustion gases or vapours possible in the event of fire.

Instructions

Suppress (knock down) gases/vapors/mists with a water spray jet.

Firefighter Protection

In the event of fire, wear self-contained breathing apparatus.

06

Accidental Release Measures

Spill cleanup procedures, containment, and environmental protection

Emergency procedures

Avoid inhalation of dusts. Avoid substance contact. Ensure adequate ventilation. Evacuate the danger area, observe emergency procedures, consult an expert.

Environmental

Do not let product enter drains.

Cleanup methods

Take up dry. Clean up affected area.

—

Related Products

Similar products with comparable safety profiles

07

Handling and Storage

Safe handling precautions, storage conditions, and workplace requirements

Handling

For precautions see section 2.2.

Storage

Tightly closed. Dry.

08

Exposure Controls / PPE

Occupational exposure limits, engineering controls, and protective equipment

Hands

Full contact: Material: Nitrile rubber, Minimum layer thickness: 0.11 mm, Break through time: 480 min, Material tested: KCL 741 Dermatril® L. Splash contact: Material: Nitrile rubber, Minimum layer thickness: 0.11 mm, Break through time: 480 min, Material tested: KCL 741 Dermatril® L. This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN374 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell, Internet: www.kcl.de).

Eyes

Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Safety glasses

Respiratory

Where risk assessment shows air-purifying respirators are appropriate use a dust mask type N95 (US) or type P1 (EN 143) respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).

Skin/Body

protective clothing

Environmental

Do not let product enter drains.

09

Physical and Chemical Properties

Appearance, physical state, melting point, boiling point, and material characteristics

Language Code
---
Physical State
solid
Physical State Data
solid
State Under Standard Conditions
---
Appearance
powder
Colour
white
Colour Intensity
---
Form
powder
Odor
odorless
Odor Threshold
Not applicable
Ph
5.5 - 6.5 at 20 °C (68 °F) - (saturated solution)
Melting Point
165.6 - 168 °C (330.1 - 334 °F) at 980.4 hPa - OECD Test Guideline 102
Boiling Point
> 250 °C > 482 °F at 980.1 hPa - OECD Test Guideline 103
Flash Point
184.6 °C (364.3 °F) - Pensky-Martens closed cup - ISO 2719
Freezing Point
---
Softening Point
---
Solidification Point
---
Cloud Point
---
Crystallisation Point
---
Relative Evaporation Rate
---
Evaporation Rate
---
Vapor Pressure
---
Vapor Density
---
Relative Density
1.293 g/cm³ at 21 °C (70 °F)
Bulk Density
---
Density
---
Flammability
---
Upper Explosive Limit
---
Lower Explosive Limit
---
Explosive Limits
---
Auto Ignition Temperature
---
Decomposition Temperature
> 180 °C (> 356 °F) -
Solubility
Ethanol at 20 °C (68 °F) - soluble
Partition Coefficient
log Pow: 1.098 at 25 °C (77 °F) - Bioaccumulation is not expected.
Solubility In Water
19 g/l at 28 °C (82 °F) - completely soluble
Solubility In Fat
---
Molecular Weight
---
Voc Content
---
Metal Corrosion
---
Dynamic Viscosity
---
Kinematic Viscosity
---
Properties Status
---
10

Stability and Reactivity

Chemical stability, hazardous reactions, and incompatible materials

Stability

The product is chemically stable under standard ambient conditions (room temperature).

Reactivity

Forms explosive mixtures with air on intense heating. A range from approx. 15 Kelvin below the flash point is to be rated as critical. The following applies in general to flammable organic substances and mixtures: in correspondingly fine distribution, when whirled up a dust explosion potential may generally be assumed.

Hazardous reactions

No data available

Avoid

Strong heating.

Incompatible

No data available

Decomposition

Hazardous decomposition products formed under fire conditions. - Carbon oxides, Nitrogen oxides (NOx). Other decomposition products - No data available

12

Ecological Information

Environmental toxicity, biodegradation, and bioaccumulation data

12.1 Toxicity

Toxicity to fish: flow-through test LC50 - Oryzias latipes (Orange-red killifish) - 160 mg/l - 96 h (OECD Test Guideline 203) Toxicity to bacteria: Remarks: (Lit.)(4'-hydroxyacetanilide)

12.2 Persistence and degradability

Biodegradability: Result: 57% - Not readily biodegradable. (OECD Test Guideline 301F)

12.3 Bioaccumulative potential

No data available

12.4 Mobility in soil

No data available

12.5 Results of PBT and vPvB assessment

PBT/vPvB assessment not available as chemical safety assessment not required/not conducted

PBT/vPvB assessment not available as chemical safety assessment not required/not conducted

12.6 Other adverse effects

No data available

No data available

13

Disposal Considerations

Waste treatment methods, disposal recommendations, and waste codes

Treatment

Waste material must be disposed of in accordance with the national and loc No mixing with other waste.

Disposal

Waste material must be disposed of in accordance with the national and loc No mixing with other waste.

14

Transport Information

UN numbers, shipping names, transport classes, and regulatory requirements

15

Regulatory Information

Chemical regulations, safety assessments, and compliance status

?

Frequently Asked Questions

Common questions about safety, handling, and properties

What is the hazard signal word for Acetaminophen?

The signal word is warning.

What is the physical form of Acetaminophen?

Acetaminophen is a solid appearing as powder with white color. It has odorless odor.

What is the solubility of Acetaminophen?

Ethanol at 20 °C (68 °F) - soluble

What is Acetaminophen used for?

Laboratory chemicals, Synthesis of substances

What are the hazard statements for Acetaminophen?

This substance has 1 hazard statement:

  • H302: Harmful if swallowed.

What is the melting point of Acetaminophen?

The melting point is 165.6 - 168 °C (330.1 - 334 °F) at 980.4 hPa - OECD Test Guideline 102 and the boiling point is > 250 °C > 482 °F at 980.1 hPa - OECD Test Guideline 103.