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Safety Data Sheet EN

Elecsys sFlt-1

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01

Identification

Product identifiers, regulatory numbers, and supplier information

Product Information

Product Name
Elecsys sFlt-1
Product Code
07027818190

Regulatory Identifiers

CAS Number
N/A

Manufacturers & Suppliers

R

Roche Diagnostics Limited

manufacturer

Charles Avenue, Burgess Hill, RH15 9RY West Sussex, United Kingdom

+44 1444 256000

R

Roche Diagnostics Ltd.

manufacturer

Emergency Contacts

Roche Diagnostics Ltd. - Health, Safety & Environment

+44 1444 256500

Roche Diagnostics Ltd. - Health, Safety & Environment

+44 7802 260498

Roche Diagnostics Ltd. - Product Safety / Vigilance

+44 1444 256561

Roche Diagnostics Ltd. - Product Safety / Vigilance

+44 7710 391653

NPIS

+44 844 892 0111

NHS Direct

+44 845 4647

NHS 24

+44 8454 242424

02

Hazard Identification

GHS classification, signal word, pictograms, and hazard statements

Classified warning

Hazard Classifications

GHS Pictograms

GHS07 - Health hazard

GHS07

Hazard Statements

H317 May cause an allergic skin reaction.

Precautionary Statements

P261 Avoid breathing mist or vapours.
P272 Contaminated work clothing should not be allowed out of the workplace.
P280 Wear protective gloves.
P333 + P313 If skin irritation or rash occurs: Get medical advice/ attention.
P362 + P364 Take off contaminated clothing and wash it before reuse.
P501 Dispose of contents/ container to an approved waste disposal plant.

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03

Composition / Information on Ingredients

Chemical components, concentration ranges, and hazardous substance identification

Type mixture
Chemical Name CAS Number Concentration Hazardous
2-methyl-2H-isothiazol-3-one hydrochloride EC: 247-499-3 26172-54-3 0.0025 - 0.025% Yes
04

First Aid Measures

Emergency procedures for chemical exposure incidents

Inhalation

Move to fresh air. If unconscious, place in recovery position and seek medical advice. If symptoms persist, call a physician.

Skin contact

If on skin, rinse well with water.

Eye contact

Immediately flush eye(s) with plenty of water. Remove contact lenses. Protect unharmed eye. Keep eye wide open while rinsing. If eye irritation persists, consult a specialist.

Ingestion

Keep respiratory tract clear. If symptoms persist, call a physician. Rinse mouth with water.

Medical Treatment

The first aid procedure should be established in consultation with the doctor responsible for industrial medicine.

05

Firefighting Measures

Extinguishing media, specific hazards, and firefighter protection

Suitable media

Use extinguishing measures that are appropriate to local circumstances and the surrounding environment.

Unsuitable media

High volume water jet

Specific hazards

No information available.

Instructions

Standard procedure for chemical fires.

Firefighter Protection

Wear self-contained breathing apparatus for firefighting if necessary.

06

Accidental Release Measures

Spill cleanup procedures, containment, and environmental protection

Emergency procedures

Use personal protective equipment. Refer to protective measures listed in sections 7 and 8.

Environmental

Prevent product from entering drains. Prevent further leakage or spillage if safe to do so.

Cleanup methods

Soak up with inert absorbent material (e.g. sand, silica gel, acid binder, universal binder, sawdust). Keep in suitable, closed containers for disposal.

Materials: inert absorbent material (e.g. sand, silica gel, acid binder, universal binder, sawdust)

Related Products

Similar products with comparable safety profiles

07

Handling and Storage

Safe handling precautions, storage conditions, and workplace requirements

Handling

Do not breathe vapours/dust. Avoid exposure - obtain special instructions before use. Avoid contact with skin and eyes. For personal protection see section 8. Smoking, eating and drinking should be prohibited in the application area. Persons susceptible to skin sensitisation problems or asthma, allergies, chronic or recurrent respiratory disease should not be employed in any process in which this mixture is being used.

Storage

Keep container tightly closed in a dry and well-ventilated place. See label, package insert or internal guidelines.

Hygiene

Wash hands before breaks and at the end of workday.

Fire prevention

Normal measures for preventive fire protection.

08

Exposure Controls / PPE

Occupational exposure limits, engineering controls, and protective equipment

Engineering

No data available

Hands

In case of contact through splashing: Nitrile rubber, Break through time: >30 min, Glove thickness: >0,11 mm. In case of full contact: butyl-rubber, Break through time: >480 min, Glove thickness: >0,4 mm. Remarks: The selected protective gloves have to satisfy the specifications of Regulation (EU) 2016/425 and the standard EN 374 derived from it. This recommendation is only valid for the product mentioned in the safety data sheet and provided by us and for the application specified by us. Please observe the instructions regarding permeability and breakthrough time which are provided by the supplier of the gloves. Also take into consideration the specific local conditions under which the product is used, such as the danger of cuts, abrasion, and the contact time. The suitability for a specific workplace should be discussed with the producers of the protective gloves.

Eyes

Eye wash bottle with pure water, Tightly fitting safety goggles, Use eye protection according to EN 166.

Skin/Body

Impervious clothing, Choose body protection according to the amount and concentration of the dangerous substance at the work place.

09

Physical and Chemical Properties

Appearance, physical state, melting point, boiling point, and material characteristics

Physical State
liquid
Physical State Data
liquid
State Under Standard Conditions
---
Appearance
colourless, clear, red brown
Colour
colourless
Colour Intensity
---
Form
---
Odor
none, odourless
Odor Threshold
No data available
Ph
7,2
Melting Point
No data available
Boiling Point
No data available
Flash Point
does not flash
Freezing Point
No data available
Softening Point
---
Solidification Point
---
Cloud Point
---
Crystallisation Point
---
Relative Evaporation Rate
---
Evaporation Rate
No data available
Vapor Pressure
No data available
Vapor Density
---
Relative Density
No data available
Bulk Density
---
Density
1,022 g/cm3
Flammability
Does not sustain combustion.
Upper Explosive Limit
No data available
Lower Explosive Limit
No data available
Explosive Limits
---
Auto Ignition Temperature
No data available
Decomposition Temperature
No data available
Solubility
completely miscible
Partition Coefficient
No data available
Solubility In Water
completely miscible
Solubility In Fat
---
Molecular Weight
---
Voc Content
---
Metal Corrosion
---
Dynamic Viscosity
No data available
Kinematic Viscosity
No data available
Properties Status
---
10

Stability and Reactivity

Chemical stability, hazardous reactions, and incompatible materials

Stability

Stable under normal conditions.

Reactivity

No dangerous reaction known under conditions of normal use.

Hazardous reactions

No decomposition if stored and applied as directed.

Avoid

No data available

Incompatible

No data available

Decomposition

No data available

12

Ecological Information

Environmental toxicity, biodegradation, and bioaccumulation data

12.1 Toxicity

Components:

12.1 Toxicity

2-methyl-2H-isothiazol-3-one hydrochloride: Toxicity to fish : LC50 (Oncorhynchus mykiss (rainbow trout)): 4,77 mg/l Exposure time: 96 h Test Type: flow-through test Method: OECD Test Guideline 203 Toxicity to daphnia and other aquatic invertebrates : EC50 (Daphnia magna (Water flea)): 2,33 mg/l Exposure time: 48 h Test Type: static test Method: OECD Test Guideline 202 Toxicity to algae/aquatic plants : ErC50 (Pseudokirchneriella subcapitata (green algae)): 0,289 mg/l Exposure time: 72 h Test Type: static test Method: OECD Test Guideline 201 M-Factor (Acute aquatic toxicity) : 1 Toxicity to daphnia and other aquatic invertebrates (Chronic toxicity) : NOEC: 0,0442 mg/l Exposure time: 21 d Species: Daphnia magna (Water flea) Method: OECD Test Guideline 211

12.1 Toxicity

2-methyl-2H-isothiazol-3-one hydrochloride: Toxicity to fish : LC50 (Oncorhynchus mykiss (rainbow trout)): 4,77 mg/l Exposure time: 96 h Test Type: flow-through test Method: OECD Test Guideline 203 Toxicity to daphnia and other aquatic invertebrates : EC50 (Daphnia magna (Water flea)): 2,33 mg/l Exposure time: 48 h Test Type: static test Method: OECD Test Guideline 202 Toxicity to algae/aquatic plants : ErC50 (Pseudokirchneriella subcapitata (green algae)): 0,289 mg/l Exposure time: 72 h Test Type: static test Method: OECD Test Guideline 201 M-Factor (Acute aquatic toxicity) : 1 Toxicity to daphnia and other aquatic invertebrates (Chronic toxicity) : NOEC: 0,0442 mg/l Exposure time: 21 d Species: Daphnia magna (Water flea) Method: OECD Test Guideline 211

12.1 Toxicity

2-methyl-2H-isothiazol-3-one hydrochloride: Toxicity to fish : LC50 (Oncorhynchus mykiss (rainbow trout)): 4,77 mg/l Exposure time: 96 h Test Type: flow-through test Method: OECD Test Guideline 203 Toxicity to daphnia and other : EC50 (Daphnia magna (Water flea)): 2,33 mg/l aquatic invertebrates Exposure time: 48 h Test Type: static test Method: OECD Test Guideline 202 Toxicity to algae/aquatic : ErC50 (Pseudokirchneriella subcapitata (green algae)): 0,289 plants mg/l Exposure time: 72 h Test Type: static test Method: OECD Test Guideline 201 M-Factor (Acute aquatic tox- : 1 icity) Toxicity to daphnia and other : NOEC: 0,0442 mg/l aquatic invertebrates (Chron- Exposure time: 21 d ic toxicity) Species: Daphnia magna (Water flea) Method: OECD Test Guideline 211

12.2 Persistence and degradability

2-methyl-2H-isothiazol-3-one hydrochloride: Biodegradability : Test Type: aerobic Result: Not readily biodegradable. Biodegradation: 0 % Exposure time: 28 d Method: OECD Test Guideline 301B

The substance is not readily biodegradable.

12.2 Persistence and degradability

2-methyl-2H-isothiazol-3-one hydrochloride: Biodegradability : Test Type: aerobic Result: Not readily biodegradable. Biodegradation: 0 % Exposure time: 28 d Method: OECD Test Guideline 301B

12.2 Persistence and degradability

2-methyl-2H-isothiazol-3-one hydrochloride: Biodegradability : Test Type: aerobic Result: Not readily biodegradable. Biodegradation: 0 % Exposure time: 28 d Method: OECD Test Guideline 301B

Not readily biodegradable.

12.3 Bioaccumulative potential

### Components:

12.3 Bioaccumulative potential

2-methyl-2H-isothiazol-3-one hydrochloride: Bioaccumulation : Remarks: No bioaccumulation is to be expected (log Pow <= 4). Partition coefficient: n-octanol/water : log Pow: ca. -0,44 (20 °C) Method: OECD Test Guideline 107

12.3 Bioaccumulative potential

2-methyl-2H-isothiazol-3-one hydrochloride: Bioaccumulation : Remarks: No bioaccumulation is to be expected (log Pow <= 4). Partition coefficient: n-octanol/water : log Pow: ca. -0,44 (20 °C) Method: OECD Test Guideline 107

12.3 Bioaccumulative potential

2-methyl-2H-isothiazol-3-one hydrochloride: Bioaccumulation : Remarks: No bioaccumulation is to be expected (log Pow <= 4). Partition coefficient: n-octanol/water : log Pow: ca. -0,44 (20 °C) Method: OECD Test Guideline 107

12.4 Mobility in soil

R1 No data available R2 No data available SA Coat-Beads No data available

12.5 Results of PBT and vPvB assessment

R1 Not relevant R2 Not relevant SA Coat-Beads Not relevant

12.6 Endocrine disrupting properties

Product: Assessment: The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher. R1 Product: Assessment: The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher. R2 Assessment: The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher. SA Coat-Beads Assessment: The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher.

The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher.

12.7 Other adverse effects

No data available # R1 No data available # R2 No data available # SA Coat-Beads No data available

No data available for the listed components.

13

Disposal Considerations

Waste treatment methods, disposal recommendations, and waste codes

Treatment

Send to a licensed waste management company. Can be disposed as waste water, when in compliance with local regulations.

Disposal

Do not contaminate ponds, waterways or ditches with chemical or used container. Send to a licensed waste management company.

14

Transport Information

UN numbers, shipping names, transport classes, and regulatory requirements

15

Regulatory Information

Chemical regulations, safety assessments, and compliance status

Safety, health and environmental regulations/legislation specific for the substance or mixture

Chemical Safety Assessment Performed

Take note of Directive 94/33/EC on the protection of young people at work or stricter national regulations, where applicable.

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Frequently Asked Questions

Common questions about safety, handling, and properties

What is the hazard signal word for Elecsys sFlt-1?

The signal word is warning.

What is the physical form of Elecsys sFlt-1?

Elecsys sFlt-1 is a liquid appearing as colourless, clear, red brown with colourless color. It has none, odourless odor.

What is the solubility of Elecsys sFlt-1?

completely miscible

What are the hazard statements for Elecsys sFlt-1?

This substance has 1 hazard statement:

  • H317: May cause an allergic skin reaction.

What is the melting point of Elecsys sFlt-1?

The melting point is No data available and the boiling point is No data available.