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Safety Data Sheet EN

TRIS(HYDROXYMETHYL)AMINOMETHANE

CAS 77-86-1

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01

Identification

Product identifiers, regulatory numbers, and supplier information

Product Information

Product Name
TRIS(HYDROXYMETHYL)AMINOMETHANE
Chemical Name
tris(hydroxymethyl)aminomethane
Synonyms
1,1,1-tris(hydroxymethyl)-, 1,1,1-tris(hydroxymethyl)methylamine, 1,3-propanediol, 2-amino-2-(hydroxymethyl)-, 2-amino-1,3-dihydroxy-2-(hydroxymethyl)propane, 2-amino-2-(hydroxymethyl)-1,3-propanediol, 2-amino-2-(hydroxymethyl)propane-1,3-diol, Addex-tham methylamine,, C4-H11-N-O3, Fluka 93362, Fris Biochemical Grade 90080, H2NC(CH2OH)3, Pehanorm, Sigma T8524, THAM, THAM-E, TRIS Buffer t, TRIS-AMINO, Talatrol, Tris Base, Tris amino, Tris-steril, Trisamine, Trisaminol, Trizma, Trometamol, Tromethamine, Tromethane, Tromethanmin, aminotrimethylolmethane, aminotris(hydroxymethyl)methane, trimethylol aminomethane, tris amine buffer, tris(hydroxylmethyl)methylamine, tris(hydroxymethyl)aminomethane ultra, tris(hydroxymethyl)methylamine GPR, tris(hydroxymethyl)methylamine UNIVAR, tris(hydroxymetyl)methanamine

Regulatory Identifiers

CAS Number
77-86-1 Check regulations →

Identified Uses

Used as an emulsifying agent for oils, fats, waxes, cosmetic cream, lotions. Used as an absorbent for acidic gases, as a buffer. In medicine as an alkalinising agent in treatment of metabolic acidosis.

Manufacturers & Suppliers

VWR International, Pty Ltd logo

VWR International, Pty Ltd

manufacturer

Unit 1/31 Archimedes Place 4172 QLD Australia

61 7 3009 4100 ; 1300 727 696

http://au.vwr.com

Emergency Contacts

Emergency Contact

61 7 3009 4100

Emergency Contact

1300 727 696

Emergency Contact

61 7 3009 4100

Emergency Contact

1300 727 696

02

Hazard Identification

GHS classification, signal word, pictograms, and hazard statements

Classified warning

Hazard Classifications

Skin Irrit. Cat. 2
Eye Irrit. Cat. 2
STOT SE Cat. 3

GHS Pictograms

GHS07 - Health hazard

GHS07

Hazard Statements

H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation

Precautionary Statements

P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302 + P352 IF ON SKIN: Wash with plenty of water and soap
P304 + P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312 Call a POISON CENTER/doctor/physician/first aider/if you feel unwell.
P321 Specific treatment (see advice on this label).
P332 + P313 If skin irritation occurs: Get medical advice/attention.
P337 + P313 If eye irritation persists: Get medical advice/attention.
P362 + P364 Take off contaminated clothing and wash it before reuse.
P403 + P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to authorised chemical landfill or if organic to high temperature incineration

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03

Composition / Information on Ingredients

Chemical components, concentration ranges, and hazardous substance identification

Type substance
Chemical Name CAS Number Concentration Hazardous
tris(hydroxymethyl)aminomethane 77-86-1 98% No

See section above for composition of Substances

04

First Aid Measures

Emergency procedures for chemical exposure incidents

Inhalation

If fumes or combustion products are inhaled remove from contaminated area. Lay patient down. Keep warm and rested. Prostheses such as false teeth, which may block airway, should be removed, where possible, prior to initiating first aid procedures. Apply artificial respiration if not breathing, preferably with a demand valve resuscitator, bag-valve mask device, or pocket mask as trained. Perform CPR if necessary. Transport to hospital, or doctor, without delay.

Skin contact

Immediately remove all contaminated clothing, including footwear. Flush skin and hair with running water (and soap if available). Seek medical attention in event of irritation.

Eye contact

Wash out immediately with fresh running water. Ensure complete irrigation of the eye by keeping eyelids apart and away from eye and moving the eyelids by occasionally lifting the upper and lower lids. Seek medical attention without delay; if pain persists or recurs seek medical attention. Removal of contact lenses after an eye injury should only be undertaken by skilled personnel.

Ingestion

Immediately give a glass of water. First aid is not generally required. If in doubt, contact a Poisons Information Centre or a doctor.

Immediate Medical Attention

Seek medical attention without delay (eye); Seek medical attention in event of irritation (skin); Transport to hospital, or doctor, without delay (inhalation).

Medical Treatment

Treat symptomatically.

05

Firefighting Measures

Extinguishing media, specific hazards, and firefighter protection

Suitable media

Water spray or fog. Foam. Dry chemical powder. BCF (where regulations permit).

Specific hazards

Combustible solid which burns but propagates flame with difficulty; it is estimated that most organic dusts are combustible (circa 70%) - according to the circumstances under which the combustion process occurs, such materials may cause fires and / or dust explosions. Organic powders when finely divided over a range of concentrations regardless of particulate size or shape and suspended in air or some other oxidizing medium may form explosive dust-air mixtures and result in a fire or dust explosion (including secondary explosions). Avoid generating dust, particularly clouds of dust in a confined or unventilated space as dusts may form an explosive mixture with air, and any source of ignition, i.e. flame or spark, will cause fire or explosion. Dust clouds generated by the fine grinding of the solid are a particular hazard; accumulations of fine dust (420 micron or less) may burn rapidly and fiercely if ignited - particles exceeding this limit will generally not form flammable dust clouds; once initiated, however, larger particles up to 1400 microns diameter will contribute to the propagation of an explosion.

Instructions

Alert Fire Brigade and tell them location and nature of hazard. Prevent, by any means available, spillage from entering drains or water courses. Use water delivered as a fine spray to control fire and cool adjacent area.

Firefighter Protection

Wear breathing apparatus plus protective gloves.

06

Accidental Release Measures

Spill cleanup procedures, containment, and environmental protection

Emergency procedures

Minor Spills: Clean up all spills immediately. Major Spills: Advise personnel in area.

Small spill

Clean up all spills immediately.

Large spill

Advise personnel in area.

Cleanup methods

Use dry clean up procedures

Related Products

Similar products with comparable safety profiles

07

Handling and Storage

Safe handling precautions, storage conditions, and workplace requirements

Handling

Avoid all personal contact, including inhalation. Wear protective clothing when risk of exposure occurs.

Storage

Store in a cool, dry area protected from environmental extremes. Store away from incompatible materials and foodstuff containers.

08

Exposure Controls / PPE

Occupational exposure limits, engineering controls, and protective equipment

09

Physical and Chemical Properties

Appearance, physical state, melting point, boiling point, and material characteristics

Physical State
Divided Solid
Physical State Data
solid
State Under Standard Conditions
---
Appearance
Large irregular, odourless white crystals.
Colour
---
Colour Intensity
---
Form
---
Odor
Not Available
Odor Threshold
Not Available
Ph
Not applicable
Melting Point
169 °C
Boiling Point
219 °C
Flash Point
Not Available
Freezing Point
---
Softening Point
---
Solidification Point
---
Cloud Point
---
Crystallisation Point
---
Relative Evaporation Rate
---
Evaporation Rate
Not applicable
Vapor Pressure
Not applicable.
Vapor Density
Not applicable.
Relative Density
Not available.
Bulk Density
---
Density
---
Flammability
Not Available
Upper Explosive Limit
Not Available
Lower Explosive Limit
Not Available
Explosive Limits
---
Auto Ignition Temperature
Not available.
Decomposition Temperature
Not available.
Solubility
---
Partition Coefficient
Not Available
Solubility In Water
Miscible
Solubility In Fat
---
Molecular Weight
121.14
Voc Content
---
Metal Corrosion
---
Dynamic Viscosity
---
Kinematic Viscosity
Not Applicable
Properties Status
---
10

Stability and Reactivity

Chemical stability, hazardous reactions, and incompatible materials

Stability

Presence of incompatible materials. Product is considered stable. Hazardous polymerisation will not occur.

Reactivity

See section 7

Hazardous reactions

See section 7

Avoid

See section 7

Incompatible

See section 7

Decomposition

See section 5

12

Ecological Information

Environmental toxicity, biodegradation, and bioaccumulation data

The data for this section has not been processed yet.

13

Disposal Considerations

Waste treatment methods, disposal recommendations, and waste codes

The data for this section has not been processed yet.

14

Transport Information

UN numbers, shipping names, transport classes, and regulatory requirements

15

Regulatory Information

Chemical regulations, safety assessments, and compliance status

The data for this section has not been processed yet.

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Frequently Asked Questions

Common questions about safety, handling, and properties

What other names is TRIS(HYDROXYMETHYL)AMINOMETHANE known by?

TRIS(HYDROXYMETHYL)AMINOMETHANE is also known as: 1,1,1-tris(hydroxymethyl)-, 1,1,1-tris(hydroxymethyl)methylamine, 1,3-propanediol, 2-amino-2-(hydroxymethyl)-, 2-amino-1,3-dihydroxy-2-(hydroxymethyl)propane, 2-amino-2-(hydroxymethyl)-1,3-propanediol, 2-amino-2-(hydroxymethyl)propane-1,3-diol, Addex-tham methylamine,, C4-H11-N-O3, Fluka 93362, Fris Biochemical Grade 90080, H2NC(CH2OH)3, Pehanorm, Sigma T8524, THAM, THAM-E, TRIS Buffer t, TRIS-AMINO, Talatrol, Tris Base, Tris amino, Tris-steril, Trisamine, Trisaminol, Trizma, Trometamol, Tromethamine, Tromethane, Tromethanmin, aminotrimethylolmethane, aminotris(hydroxymethyl)methane, trimethylol aminomethane, tris amine buffer, tris(hydroxylmethyl)methylamine, tris(hydroxymethyl)aminomethane ultra, tris(hydroxymethyl)methylamine GPR, tris(hydroxymethyl)methylamine UNIVAR, tris(hydroxymetyl)methanamine

What is the hazard signal word for TRIS(HYDROXYMETHYL)AMINOMETHANE?

The signal word is warning.

What is the physical form of TRIS(HYDROXYMETHYL)AMINOMETHANE?

TRIS(HYDROXYMETHYL)AMINOMETHANE is a divided solid appearing as large irregular, odourless white crystals. . It has not available odor.

What is TRIS(HYDROXYMETHYL)AMINOMETHANE used for?

Used as an emulsifying agent for oils, fats, waxes, cosmetic cream, lotions. Used as an absorbent for acidic gases, as a buffer. In medicine as an alkalinising agent in treatment of metabolic acidosis.

What are the hazard statements for TRIS(HYDROXYMETHYL)AMINOMETHANE?

This substance has 3 hazard statements:

  • H315: Causes skin irritation
  • H319: Causes serious eye irritation
  • H335: May cause respiratory irritation

What is the melting point of TRIS(HYDROXYMETHYL)AMINOMETHANE?

The melting point is 169 °C and the boiling point is 219 °C.