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Safety Data Sheet EN

CHIR99021

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01

Identification

Product identifiers, regulatory numbers, and supplier information

Product Information

Product Name
CHIR99021
Chemical Name
6-[[2-[[4-(2,4-dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)-2-pyrimidinyl]amino]ethyl]amino]-3-pyridinecarbonitirile
Synonyms
CT 99021

Regulatory Identifiers

CAS Number
N/A

Identified Uses

Laboratory chemicals

Uses advised against

No information available

Manufacturers & Suppliers

S

STEMCELL Technologies SARL

manufacturer

40 Rue des Berges, Miniparc Polytec, Bâtiment Sirocco, 38000 Grenoble, France

+33 (0) 4 76 04 75 30

S

STEMCELL Technologies Germany GmbH

manufacturer

Stolberger Str. 200, 50933, Köln, Germany

+33 (0) 4 76 04 75 30

S

STEMCELL Technologies UK Ltd.

manufacturer

Building 7100, Cambridge Research Park, Beach Drive, Waterbeach, Cambridge, UK, CB25 9TL

+33 (0) 4 76 04 75 30

Emergency Contacts

Emergency Contact

112

02

Hazard Identification

GHS classification, signal word, pictograms, and hazard statements

Classified danger

Hazard Classifications

Acute Tox. Cat. 2 H300
Skin Irrit. Cat. 2 H315
Eye Irrit. Cat. 2 H319
STOT SE Cat. 3 H335

GHS Pictograms

GHS06 - Acute toxicity

GHS06

Hazard Statements

H300 Fatal if swallowed
H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation

Precautionary Statements

P301 + P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor

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03

Composition / Information on Ingredients

Chemical components, concentration ranges, and hazardous substance identification

Type substance
Chemical Name CAS Number Concentration Hazardous
6-[[2-[[4-(2,4-dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)-2-pyrimidinyl]amino]ethyl]amino]-3-pyridinecarboniti 252917-06-9 100% Yes
04

First Aid Measures

Emergency procedures for chemical exposure incidents

Inhalation

Remove to fresh air. IF exposed or concerned: Get medical advice/attention. Get medical attention immediately if symptoms occur.

Skin contact

Wash off immediately with soap and plenty of water for at least 15 minutes. Get medical attention if irritation develops and persists.

Eye contact

Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Keep eye wide open while rinsing. Remove contact lenses, if present and easy to do. Continue rinsing. Get medical attention if irritation develops and persists. Do not rub affected area.

Ingestion

Get immediate medical advice/attention. Do NOT induce vomiting. Clean mouth with water and drink afterwards plenty of water. Never give anything by mouth to an unconscious person.

Immediate Medical Attention

Immediate medical attention is required.

Medical Treatment

Treat symptomatically.

05

Firefighting Measures

Extinguishing media, specific hazards, and firefighter protection

Suitable media

Use extinguishing measures that are appropriate to local circumstances and the surrounding environment.

Unsuitable media

No information available.

Specific hazards

No information available.

Firefighter Protection

Firefighters should wear self-contained breathing apparatus and full firefighting turnout gear. Use personal protection equipment.

06

Accidental Release Measures

Spill cleanup procedures, containment, and environmental protection

Emergency procedures

Ensure adequate ventilation. Use personal protective equipment as required. Evacuate personnel to safe areas. Avoid contact with skin, eyes or clothing.

Environmental

Prevent further leakage or spillage if safe to do so.

Cleanup methods

Take up mechanically, placing in appropriate containers for disposal.

—

Related Products

Similar products with comparable safety profiles

07

Handling and Storage

Safe handling precautions, storage conditions, and workplace requirements

Handling

Handle in accordance with good industrial hygiene and safety practice. Avoid contact with skin, eyes or clothing. Do not eat, drink or smoke when using this product. Take off contaminated clothing and wash before reuse. Ensure adequate ventilation. Avoid breathing vapors or mists. In case of insufficient ventilation, wear suitable respiratory equipment.

Storage

Store locked up. Keep out of the reach of children. Store in accordance with information listed on the Product Information Sheet (PIS).

Hygiene

Do not eat, drink or smoke when using this product. Wash hands before breaks and immediately after handling the product. Wear suitable gloves and eye/face protection. Avoid contact with skin, eyes or clothing.

08

Exposure Controls / PPE

Occupational exposure limits, engineering controls, and protective equipment

Hands

Wear suitable gloves. Impervious gloves.

Eyes

If splashes are likely to occur, wear safety glasses with side-shields.

Respiratory

No protective equipment is needed under normal use conditions. If exposure limits are exceeded or irritation is experienced, ventilation and evacuation may be required.

Skin/Body

Wear suitable protective clothing. Long sleeved clothing.

Environmental

No information available.

09

Physical and Chemical Properties

Appearance, physical state, melting point, boiling point, and material characteristics

Language Code
---
Physical State
Solid
Physical State Data
solid
State Under Standard Conditions
---
Appearance
Crystalline
Colour
No information available
Colour Intensity
---
Form
---
Odor
No data available.
Odor Threshold
No data available
Ph
No data available
Melting Point
No data available
Boiling Point
No data available
Flash Point
No data available
Freezing Point
---
Softening Point
---
Solidification Point
---
Cloud Point
---
Crystallisation Point
---
Relative Evaporation Rate
---
Evaporation Rate
No data available
Vapor Pressure
No data available
Vapor Density
No data available
Relative Density
No data available
Bulk Density
---
Density
---
Flammability
No data available
Upper Explosive Limit
No data available
Lower Explosive Limit
No data available
Explosive Limits
---
Auto Ignition Temperature
No data available
Decomposition Temperature
No data available
Solubility
~2.5 mg/mL in DMSO; ~1.4 mg/mL in PBS (pH 7.2);
Partition Coefficient
No data available
Solubility In Water
No data available
Solubility In Fat
---
Molecular Weight
465.3
Voc Content
---
Metal Corrosion
---
Dynamic Viscosity
No data available
Kinematic Viscosity
No data available
Properties Status
---
10

Stability and Reactivity

Chemical stability, hazardous reactions, and incompatible materials

Stability

Stable under recommended transport or storage conditions.

Reactivity

No information available.

Hazardous reactions

None under normal processing.

Avoid

None known based on information supplied.

Incompatible

Strong acids. Avoid release into the environment. Strong oxidizing agents.

Decomposition

Carbon dioxide (CO2). Carbon monoxide. Hydrogen cyanide. Nitrogen oxides (NOx). Phosgene.

12

Ecological Information

Environmental toxicity, biodegradation, and bioaccumulation data

12.1. Toxicity

Ecotoxicity The environmental impact of this product has not been fully investigated. Unknown aquatic toxicity Contains 100 % of components with unknown hazards to the aquatic environment.

The environmental impact of this product has not been fully investigated. Contains 100 % of components with unknown hazards to the aquatic environment.

12.2. Persistence and degradability

Persistence and degradability No information available.

No information available.

12.3. Bioaccumulative potential

Bioaccumulation No information available.

No information available.

12.4. Mobility in soil

Mobility in soil No information available.

No information available.

12.5. Results of PBT and vPvB assessment

PBT and vPvB assessment No information available.

No information available.

12.6. Other adverse effects

Other adverse effects No information available.

No information available.

13

Disposal Considerations

Waste treatment methods, disposal recommendations, and waste codes

Treatment

Dispose of in accordance with local regulations. Dispose of waste in accordance with environmental legislation.

Disposal

Dispose of in accordance with local regulations. Dispose of waste in accordance with environmental legislation.

14

Transport Information

UN numbers, shipping names, transport classes, and regulatory requirements

UN Number
2811
Shipping Name
Toxic solids, organic, n.o.s.
Transport Class
6.1
Packing Group
III
15

Regulatory Information

Chemical regulations, safety assessments, and compliance status

Take note of Directive 98/24/EC on the protection of the health and safety of workers from the risks related to chemical agents at work

Chemical Safety Assessment Not performed
?

Frequently Asked Questions

Common questions about safety, handling, and properties

What other names is CHIR99021 known by?

CHIR99021 is also known as: CT 99021

What is the hazard signal word for CHIR99021?

The signal word is danger.

What is the physical form of CHIR99021?

CHIR99021 is a solid appearing as crystalline with no information available color. It has no data available. odor.

What is the solubility of CHIR99021?

~2.5 mg/mL in DMSO; ~1.4 mg/mL in PBS (pH 7.2);

What is CHIR99021 used for?

Laboratory chemicals

What are the hazard statements for CHIR99021?

This substance has 4 hazard statements:

  • H300: Fatal if swallowed
  • H315: Causes skin irritation
  • H319: Causes serious eye irritation
  • H335: May cause respiratory irritation

What is the melting point of CHIR99021?

The melting point is No data available and the boiling point is No data available.